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6GZN
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BU of 6gzn by Molmil
Adenine-driven structural switch from two- to three-quartet DNA G-quadruplex
分子名称: DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*AP*GP*CP*GP*GP*GP*AP*GP*AP*GP*GP*G)-3')
著者Lenarcic Zivkovic, M, Rozman, J, Plavec, J.
登録日2018-07-04
公開日2018-09-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Adenine-Driven Structural Switch from a Two- to Three-Quartet DNA G-Quadruplex.
Angew. Chem. Int. Ed. Engl., 57, 2018
2IE3
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BU of 2ie3 by Molmil
Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins
分子名称: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ...
著者Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
4CAW
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BU of 4caw by Molmil
Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a pyrazole sulphonamide ligand
分子名称: 2,6-DICHLORO-4-(2-PIPERAZIN-1-YLPYRIDIN-4-YL)-N-(1,5-DIMETHYL,3-ISOBUTYL-1H-PYRAZOL-4-YL)BENZENESULFONAMIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA
著者Robinson, D.A, Fang, W, Raimi, O.G, Blair, D.E, Harrison, J, Ruda, G.F, Lockhart, D.E.A, Torrie, L.S, Wyatt, P.G, Gilbert, I.H, Van Aalten, D.M.F.
登録日2013-10-09
公開日2014-09-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献N-Myristoyltransferase is a Cell Wall Target in Aspergillus Fumigatus.
Acs Chem.Biol., 10, 2015
6IAJ
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BU of 6iaj by Molmil
Sixty minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
分子名称: CHLORIDE ION, FE (II) ION, Ferritin, ...
著者Pozzi, C, Di Pisa, F, Mangani, S.
登録日2018-11-26
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
2IMT
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BU of 2imt by Molmil
The X-ray Structure of a Bak Homodimer Reveals an Inhibitory Zinc Binding Site
分子名称: Apoptosis regulator BAK, ZINC ION
著者Moldoveanu, T, Liu, Q, Tocilj, A, Watson, M, Shore, G.C, Gehring, K.B.
登録日2006-10-04
公開日2007-01-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site.
Mol.Cell, 24, 2006
4P9C
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BU of 4p9c by Molmil
Crystal structure of dCMP deaminase from the cyanophage S-TIM5 in complex with dCMP and dUMP
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYURIDINE-5'-MONOPHOSPHATE, Deoxycytidylate deaminase, ...
著者Marx, A, Alian, A.
登録日2014-04-03
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The First Crystal Structure of a dTTP-bound Deoxycytidylate Deaminase Validates and Details the Allosteric-Inhibitor Binding Site.
J.Biol.Chem., 290, 2015
3NFY
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BU of 3nfy by Molmil
The Structure of Human Bisphosphoglycerate Mutase to 1.94A
分子名称: Bisphosphoglycerate mutase
著者Patterson, A.F, Price, N.C, Nairn, J.
登録日2010-06-10
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Unliganded structure of human bisphosphoglycerate mutase reveals side-chain movements induced by ligand binding.
Acta Crystallogr.,Sect.F, 66, 2010
2ISO
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BU of 2iso by Molmil
Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-difluoromethylene triphosphate
分子名称: 2'-DEOXY-5'-O-[({[DIFLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL}OXY)(HYDROXY)PHOSPHORYL]GUANOSINE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ...
著者Sucato, C.A, Upton, T.G, Kashemirov, B.A, Martinek, V, Xiang, Y, Beard, W.A.
登録日2006-10-18
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta.
Biochemistry, 46, 2007
6IL9
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BU of 6il9 by Molmil
One Glycerol complexed Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
分子名称: Fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi in complex with 1 glycerol, GLYCEROL, ZINC ION
著者Choi, M.Y, Kang, L.W, Ho, T.H, Nguyen, D.Q, Lee, I.H, Lee, J.H, Park, Y.S, Park, H.J.
登録日2018-10-17
公開日2019-10-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.72005355 Å)
主引用文献Crystal structure of fructuronate-tagaturonate epimerase UxaE from Cohnella laeviribosi
To Be Published
4P80
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BU of 4p80 by Molmil
Structure of ancestral PyrR protein (AncGREENPyrR)
分子名称: Ancestral PyrR protein (Green), SULFATE ION
著者Perica, T, Kondo, Y, Tiwari, S, McLaughlin, S, Steward, A, Reuter, N, Clarke, J, Teichmann, S.A.
登録日2014-03-29
公開日2014-12-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Evolution of oligomeric state through allosteric pathways that mimic ligand binding.
Science, 346, 2014
6UZN
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BU of 6uzn by Molmil
HLA-B*15:02 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-11-15
公開日2020-11-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
6UZS
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BU of 6uzs by Molmil
HLA-B*15:01 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-11-15
公開日2020-11-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
4EMH
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BU of 4emh by Molmil
Crystal structure of SpLsm4
分子名称: Probable U6 snRNA-associated Sm-like protein LSm4
著者Jiang, S.M, Wu, D.H, Song, H.W.
登録日2012-04-12
公開日2012-06-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe.
Plos One, 7, 2012
2IC5
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BU of 2ic5 by Molmil
Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Ugochukwu, E, Yang, X, Zao, Y, Elkins, J, Gileadi, C, Burgess, N, Colebrook, S, Gileadi, O, Fedorov, O, Bunkoczi, G, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-09-12
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
To be Published
2ICJ
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BU of 2icj by Molmil
The crystal structure of human isopentenyl diphophate isomerase
分子名称: Isopentenyl-diphosphate delta isomerase, MAGNESIUM ION, SULFATE ION
著者Zheng, W, Bartlam, M, Rao, Z.
登録日2006-09-12
公開日2007-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis
J.Mol.Biol., 366, 2007
4E9T
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BU of 4e9t by Molmil
Multicopper Oxidase CueO (data6)
分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION
著者Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y.
登録日2012-03-21
公開日2013-05-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and function of the engineered multicopper oxidase CueO from Escherichia coli--deletion of the methionine-rich helical region covering the substrate-binding site.
J.Mol.Biol., 373, 2007
2INE
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BU of 2ine by Molmil
Crystal Structure of Aldose Reductase complexed with Phenylacetic Acid
分子名称: 2-PHENYLACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Harrison, D.H.T, Milne, A, Brownlee, J.M.
登録日2006-10-06
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
6I4E
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BU of 6i4e by Molmil
Crystal Structure of Plasmodium falciparum actin I in the Mg-ADP state
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin-1, ...
著者Kumpula, E.-P, Lopez, A.J, Tajedin, L, Han, H, Kursula, I.
登録日2018-11-09
公開日2019-06-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
Plos Biol., 17, 2019
4A8M
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BU of 4a8m by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
8JPN
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BU of 8jpn by Molmil
Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
分子名称: (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y.
登録日2023-06-12
公開日2024-05-22
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
Cell Res., 34, 2024
2H15
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BU of 2h15 by Molmil
Carbonic anhydrase inhibitors: Clashing with Ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme II
分子名称: Carbonic anhydrase 2, MERCURY (II) ION, N-{[(3AS,5AR,8AR,8BS)-2,2,7,7-TETRAMETHYLTETRAHYDRO-3AH-BIS[1,3]DIOXOLO[4,5-B:4',5'-D]PYRAN-3A-YL]METHYL}SULFAMIDE, ...
著者Winum, J.Y, Temperini, C, Ciattini, S, Scozzafava, A, Supuran, C.T.
登録日2006-05-16
公開日2007-03-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.
J.Med.Chem., 49, 2006
1E2N
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BU of 1e2n by Molmil
HPT + HMTT
分子名称: 6-{[4-(HYDROXYMETHYL)-5-METHYL-2,6-DIOXOHEXAHYDROPYRIMIDIN-5-YL]METHYL}-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
著者Vogt, J, Scapozza, L, Schulz, G.E.
登録日2000-05-23
公開日2001-03-31
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
6IAF
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BU of 6iaf by Molmil
Fifteen minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
分子名称: CHLORIDE ION, FE (II) ION, Ferritin, ...
著者Pozzi, C, Di Pisa, F, Mangani, S.
登録日2018-11-26
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
1E2P
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BU of 1e2p by Molmil
Thymidine kinase, DHBT
分子名称: 6-[3-HYDROXY-2-(HYDROXYMETHYL)PROPYL]-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE, SULFATE ION, THYMIDINE KINASE
著者Schulz, G.E, Kessler, U.
登録日2000-05-23
公開日2001-04-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase
Protein Sci., 10, 2001
2H74
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Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
著者Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
登録日2006-06-01
公開日2007-05-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group
To be Published

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