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3BDN
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BU of 3bdn by Molmil
Crystal Structure of the Lambda Repressor
分子名称: DNA (5'-D(*DAP*DAP*DTP*DAP*DCP*DCP*DAP*DCP*DTP*DGP*DGP*DCP*DGP*DGP*DTP*DGP*DAP*DTP*DAP*DT)-3'), DNA (5'-D(*DTP*DAP*DTP*DAP*DTP*DCP*DAP*DCP*DCP*DGP*DCP*DCP*DAP*DGP*DTP*DGP*DGP*DTP*DAP*DT)-3'), Lambda Repressor
著者Stayrook, S.E, Jaru-Ampornpan, P, Hochschild, A, Lewis, M.
登録日2007-11-15
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.909 Å)
主引用文献Crystal structure of the lambda repressor and a model for pairwise cooperative operator binding
Nature, 452, 2008
3BRJ
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BU of 3brj by Molmil
Crystal structure of mannitol operon repressor (MtlR) from Vibrio parahaemolyticus RIMD 2210633
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Mannitol operon repressor
著者Tan, K, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-12-21
公開日2008-01-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria.
J.Biol.Chem., 284, 2009
1NLA
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Solution Structure of Switch Arc, a Mutant with 3(10) Helices Replacing a Wild-Type Beta-Ribbon
分子名称: Transcriptional repressor arc
著者Cordes, M.H, Walsh, N.P, McKnight, C.J, Sauer, R.T.
登録日2003-01-06
公開日2003-03-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Switch Arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon
J.Mol.Biol., 326, 2003
1IRQ
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BU of 1irq by Molmil
Crystal structure of omega transcriptional repressor at 1.5A resolution
分子名称: omega transcriptional repressor
著者Murayama, K, Orth, P, De La Hoz, A.B, Alonso, J.C, Saenger, W.
登録日2001-10-11
公開日2001-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of omega transcriptional repressor encoded by Streptococcus pyogenes plasmid pSM19035 at 1.5 A resolution.
J.Mol.Biol., 314, 2001
1B4A
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BU of 1b4a by Molmil
STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS
分子名称: ARGININE REPRESSOR
著者Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D.
登録日1998-12-18
公開日1999-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the arginine repressor from Bacillus stearothermophilus.
Nat.Struct.Biol., 6, 1999
1B4B
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BU of 1b4b by Molmil
STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS
分子名称: ARGININE, ARGININE REPRESSOR
著者Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D.
登録日1998-12-18
公開日1999-06-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the arginine repressor from Bacillus stearothermophilus.
Nat.Struct.Biol., 6, 1999
3ERE
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BU of 3ere by Molmil
Crystal structure of the arginine repressor protein from Mycobacterium tuberculosis in complex with the DNA operator
分子名称: 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DAP*DAP*DCP*DGP*DAP*DTP*DGP*DCP*DAP*DA)-3', 5'-D(*DTP*DTP*DGP*DCP*DAP*DTP*DCP*DGP*DTP*DTP*DAP*DTP*DGP*DCP*DAP*DA)-3', Arginine repressor, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, Lu, G.J, James, M.N, TB Structural Genomics Consortium (TBSGC)
登録日2008-10-01
公開日2008-10-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the arginine repressor protein in complex with the DNA operator from Mycobacterium tuberculosis.
J.Mol.Biol., 384, 2008
3SFI
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BU of 3sfi by Molmil
Ethionamide Boosters Part 2: Combining Bioisosteric Replacement and Structure-Based Drug Design to Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
分子名称: 5,5,5-trifluoro-1-{4-[3-(1,3-thiazol-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}pentan-1-one, Transcriptional regulatory repressor protein (TETR-family)
著者Flipo, M, Desroses, M, Lecat-Guillet, N, Villemagne, B, Blondiaux, N, Leroux, F, Piveteau, C, Mathys, V, Flament, M.P, Siepmann, J, Villeret, V, Wohlkonig, A, Wintjens, R, Soror, S.H, Christophe, T, Jeon, H.K, Locht, C, Brodin, P, D prez, B, Baulard, A.R, Willand, N.
登録日2011-06-13
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Ethionamide Boosters. 2. Combining Bioisosteric Replacement and Structure-Based Drug Design To Solve Pharmacokinetic Issues in a Series of Potent 1,2,4-Oxadiazole EthR Inhibitors.
J.Med.Chem., 55, 2012
2XGD
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BU of 2xgd by Molmil
Crystal structure of a designed homodimeric variant T-A(L)A(L) of the tetracycline repressor
分子名称: CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
登録日2010-06-03
公開日2010-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
2XGC
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BU of 2xgc by Molmil
Crystal structure of a designed heterodimeric variant T-A(I)B of the tetracycline repressor
分子名称: TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
登録日2010-06-03
公開日2010-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
2XGE
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BU of 2xge by Molmil
Crystal structure of a designed heterodimeric variant T-A(A)B of the tetracycline repressor
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A.
登録日2010-06-03
公開日2010-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer.
J.Mol.Biol., 403, 2010
2XDI
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BU of 2xdi by Molmil
Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)
分子名称: TRP OPERON REPRESSOR
著者Tyler, R, Copie, V.
登録日2010-05-03
公開日2010-07-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Three-Dimensional Solution NMR Structure of Apo-L75F-Trpr, a Temperature-Sensitive Mutant of the Tryptophan Repressor Protein.
Biochemistry, 41, 2002
1O57
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CRYSTAL STRUCTURE OF THE PURINE OPERON REPRESSOR OF BACILLUS SUBTILIS
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ...
著者Sinha, S.C, Krahn, J, Shin, B.S, Tomchick, D.R, Zalkin, H, Smith, J.L.
登録日2003-04-20
公開日2003-08-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Purine Repressor of Bacillus Subtilis: A Novel Combination of Domains Adapted for Transcription Regulation
J.Bacteriol., 185, 2003
1LEB
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BU of 1leb by Molmil
SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY
分子名称: LEXA REPRESSOR DNA BINDING DOMAIN
著者Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R.
登録日1994-05-11
公開日1994-08-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy.
EMBO J., 13, 1994
1LEA
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BU of 1lea by Molmil
SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA BINDING DETERMINED BY 1H NMR SPECTROSCOPY
分子名称: LEXA REPRESSOR DNA BINDING DOMAIN
著者Fogh, R.H, Ottleben, G, Rueterjans, H, Schnarr, M, Boelens, R, Kaptein, R.
登録日1994-05-11
公開日1994-08-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the LexA repressor DNA binding domain determined by 1H NMR spectroscopy.
EMBO J., 13, 1994
3F8C
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BU of 3f8c by Molmil
Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Hoechst 33342
分子名称: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, Transcriptional regulator, PadR-like family
著者Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H.
登録日2008-11-12
公開日2008-12-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition.
Embo J., 28, 2009
3F8B
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Crystal structure of the multidrug binding transcriptional regulator LmrR in drug free state
分子名称: Transcriptional regulator, PadR-like family
著者Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H.
登録日2008-11-12
公開日2008-12-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition.
Embo J., 28, 2009
3F8F
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Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Daunomycin
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H.
登録日2008-11-12
公開日2008-12-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition.
Embo J., 28, 2009
2IU4
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BU of 2iu4 by Molmil
Dihydroxyacetone kinase operon co-activator Dha-DhaQ
分子名称: DIHYDROXYACETONE KINASE, SULFATE ION
著者Srinivas, A, Christen, S, Baumann, U, Erni, B.
登録日2006-05-27
公開日2006-06-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Regulation of the Dha Operon of Lactococcus Lactis: A Deviation from the Rule Followed by the Tetr Family of Transcription Regulators
J.Biol.Chem., 281, 2006
7CE1
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BU of 7ce1 by Molmil
Complex STRUCTURE OF TRANSCRIPTION FACTOR SghR with its COGNATE DNA
分子名称: LacI-type transcription factor, promoter DNA
著者Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G.
登録日2020-06-21
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
7CDV
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STRUCTURE OF A NOVEL VIRULENCE REGULATION FACTOR SghR
分子名称: LacI-type transcription factor
著者Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G.
登録日2020-06-20
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
7CDX
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Complex STRUCTURE OF A NOVEL VIRULENCE REGULATION FACTOR SghR with its effector sucrose
分子名称: LacI-type transcription factor, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Ye, F.Z, Wang, C, Yan, X.F, Zhang, L.H, Gao, Y.G.
登録日2020-06-20
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献Structural basis of a novel repressor, SghR, controllingAgrobacteriuminfection by cross-talking to plants.
J.Biol.Chem., 295, 2020
2ONB
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Human Thymidylate Synthase at low salt conditions with PDPA bound
分子名称: 1,2-ETHANEDIOL, PROPANE-1,3-DIYLBIS(PHOSPHONIC ACID), SULFATE ION, ...
著者Lovelace, L.L, Gibson, L.M, Lebioda, L.
登録日2007-01-23
公開日2007-04-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cooperative Inhibition of Human Thymidylate Synthase by Mixtures of Active Site Binding and Allosteric Inhibitors
Biochemistry, 46, 2007
2NVW
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Crystal sctucture of transcriptional regulator Gal80p from kluyveromymes lactis
分子名称: Galactose/lactose metabolism regulatory protein GAL80
著者Thoden, J.B, Sellick, C.A, Reece, R.J, Holden, H.M.
登録日2006-11-13
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p.
J.Biol.Chem., 282, 2007
7QZ8
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Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022

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