5CTT
 
 | |
5W4F
 | |
6D7M
 | | Crystal structure of the W184R/W231R Importin alpha mutant | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ... | | 著者 | Pedersen, L.C, London, R.E, Gabel, S.A. | | 登録日 | 2018-04-25 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.187 Å) | | 主引用文献 | Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
|
|
4MZ5
 | | Structure of importin-alpha: dUTPase NLS complex | | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | | 登録日 | 2013-09-29 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
4MZ6
 | | Structure of importin-alpha: dUTPase S11E NLS mutant complex | | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | | 登録日 | 2013-09-29 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights.
Acta Crystallogr.,Sect.D, 69, 2013
|
|
6N88
 | |
6N89
 | |
6G04
 | | NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119) | | 分子名称: | 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2 | | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | | 登録日 | 2018-03-16 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
|
|
6G03
 | | NMR Solution Structure of yeast TSR2(1-152) | | 分子名称: | Pre-rRNA-processing protein TSR2 | | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | | 登録日 | 2018-03-16 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2.
Nat Commun, 9, 2018
|
|
3BTR
 | | AR-NLS:Importin-alpha complex | | 分子名称: | Androgen receptor, Importin subunit alpha-2 | | 著者 | Cutress, M.L, Whitaker, H.C, Mills, I.G, Stewart, M, Neal, D.E. | | 登録日 | 2007-12-30 | | 公開日 | 2008-12-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the nuclear import of the human androgen receptor
J.Cell.Sci., 121, 2008
|
|
8QXX
 | | HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2 | | 分子名称: | DNA polymerase processivity factor, Importin subunit alpha-1 | | 著者 | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | | 登録日 | 2023-10-25 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
|
|
8QXW
 | | HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 | | 分子名称: | DNA polymerase processivity factor, Importin subunit alpha-1 | | 著者 | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | | 登録日 | 2023-10-25 | | 公開日 | 2023-11-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44.
Febs Lett., 598, 2024
|
|
5WUN
 | |
5WUM
 | |
8F7A
 | | Cryo-EM structure of Importin-9 bound to RanGTP | | 分子名称: | GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-9, ... | | 著者 | Bernardes, N.E, Chook, Y.M. | | 登録日 | 2022-11-18 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
5EKF
 | |
6Q83
 | | Crystal structure of the biportin Pdr6 in complex with UBC9 | | 分子名称: | Importin beta-like protein KAP122, UBC9 | | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
|
|
7VPT
 | |
7RG0
 | | Importin alpha2 in complex with MERS ORF4B R24A mutant | | 分子名称: | Importin subunit alpha-1, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RFY
 | | Importin alpha3 in complex with MERS ORF4B | | 分子名称: | Importin subunit alpha-3, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RFX
 | | Importin alpha2 in complex with MERS ORF4B | | 分子名称: | Importin subunit alpha-1, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RG2
 | | Importin alpha2 in complex with MERS ORF4B R33A mutant | | 分子名称: | Importin subunit alpha-1, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RG6
 | | Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 | | 分子名称: | Importin subunit alpha-1, Non-structural protein ORF4b | | 著者 | Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RG3
 | | Importin alpha2 in complex with MERS ORF4B R37A mutant | | 分子名称: | Importin subunit alpha-1, ORF4b | | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
7RG4
 | | Importin alpha2 in complex with p50 NLS | | 分子名称: | Importin subunit alpha-1, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit | | 著者 | Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K. | | 登録日 | 2021-07-14 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity.
Nat Commun, 13, 2022
|
|
