5CTT
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5W4F
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6D7M
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![BU of 6d7m by Molmil](/molmil-images/mine/6d7m) | Crystal structure of the W184R/W231R Importin alpha mutant | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ... | 著者 | Pedersen, L.C, London, R.E, Gabel, S.A. | 登録日 | 2018-04-25 | 公開日 | 2019-03-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.187 Å) | 主引用文献 | Variations in nuclear localization strategies among pol X family enzymes. Traffic, 2018
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4MZ5
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![BU of 4mz5 by Molmil](/molmil-images/mine/4mz5) | Structure of importin-alpha: dUTPase NLS complex | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | 登録日 | 2013-09-29 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
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4MZ6
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![BU of 4mz6 by Molmil](/molmil-images/mine/4mz6) | Structure of importin-alpha: dUTPase S11E NLS mutant complex | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin subunit alpha-1 | 著者 | Marfori, M, Rona, G, Vertessy, B.G, Kobe, B. | 登録日 | 2013-09-29 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. Acta Crystallogr.,Sect.D, 69, 2013
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6N88
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6N89
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6G04
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![BU of 6g04 by Molmil](/molmil-images/mine/6g04) | NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119) | 分子名称: | 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2 | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | 登録日 | 2018-03-16 | 公開日 | 2018-09-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun, 9, 2018
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6G03
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![BU of 6g03 by Molmil](/molmil-images/mine/6g03) | NMR Solution Structure of yeast TSR2(1-152) | 分子名称: | Pre-rRNA-processing protein TSR2 | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | 登録日 | 2018-03-16 | 公開日 | 2018-09-19 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun, 9, 2018
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3BTR
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![BU of 3btr by Molmil](/molmil-images/mine/3btr) | AR-NLS:Importin-alpha complex | 分子名称: | Androgen receptor, Importin subunit alpha-2 | 著者 | Cutress, M.L, Whitaker, H.C, Mills, I.G, Stewart, M, Neal, D.E. | 登録日 | 2007-12-30 | 公開日 | 2008-12-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for the nuclear import of the human androgen receptor J.Cell.Sci., 121, 2008
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8QXX
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![BU of 8qxx by Molmil](/molmil-images/mine/8qxx) | HCMV DNA polymerase processivity factor UL44 phosphorylated NLS 410-433 bound to mouse importin alpha 2 | 分子名称: | DNA polymerase processivity factor, Importin subunit alpha-1 | 著者 | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | 登録日 | 2023-10-25 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
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8QXW
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![BU of 8qxw by Molmil](/molmil-images/mine/8qxw) | HCMV DNA polymerase processivity factor UL44 unphosphorylated NLS 410-433 bound to mouse importin alpha 2 | 分子名称: | DNA polymerase processivity factor, Importin subunit alpha-1 | 著者 | Cross, E.M, Marin, O, Ariawan, D, Aragao, D, Cozza, G, Di Iorio, E, Forwood, J.K, Alvisi, G. | 登録日 | 2023-10-25 | 公開日 | 2023-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural determinants of phosphorylation-dependent nuclear transport of HCMV DNA polymerase processivity factor UL44. Febs Lett., 598, 2024
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5WUN
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5WUM
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8F7A
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![BU of 8f7a by Molmil](/molmil-images/mine/8f7a) | Cryo-EM structure of Importin-9 bound to RanGTP | 分子名称: | GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-9, ... | 著者 | Bernardes, N.E, Chook, Y.M. | 登録日 | 2022-11-18 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Mechanism of RanGTP priming H2A-H2B release from Kap114 in an atypical RanGTP•Kap114•H2A-H2B complex. Proc.Natl.Acad.Sci.USA, 120, 2023
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5EKF
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6Q83
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![BU of 6q83 by Molmil](/molmil-images/mine/6q83) | Crystal structure of the biportin Pdr6 in complex with UBC9 | 分子名称: | Importin beta-like protein KAP122, UBC9 | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | 登録日 | 2018-12-14 | 公開日 | 2019-05-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. J.Cell Biol., 218, 2019
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7VPT
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7RG0
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![BU of 7rg0 by Molmil](/molmil-images/mine/7rg0) | Importin alpha2 in complex with MERS ORF4B R24A mutant | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RFY
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![BU of 7rfy by Molmil](/molmil-images/mine/7rfy) | Importin alpha3 in complex with MERS ORF4B | 分子名称: | Importin subunit alpha-3, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RFX
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![BU of 7rfx by Molmil](/molmil-images/mine/7rfx) | Importin alpha2 in complex with MERS ORF4B | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RG2
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![BU of 7rg2 by Molmil](/molmil-images/mine/7rg2) | Importin alpha2 in complex with MERS ORF4B R33A mutant | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RG6
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![BU of 7rg6 by Molmil](/molmil-images/mine/7rg6) | Importin alpha2 in complex with ORF4B Bat coronavirus HKU5 | 分子名称: | Importin subunit alpha-1, Non-structural protein ORF4b | 著者 | Foster, J.K, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RG3
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![BU of 7rg3 by Molmil](/molmil-images/mine/7rg3) | Importin alpha2 in complex with MERS ORF4B R37A mutant | 分子名称: | Importin subunit alpha-1, ORF4b | 著者 | Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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7RG4
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![BU of 7rg4 by Molmil](/molmil-images/mine/7rg4) | Importin alpha2 in complex with p50 NLS | 分子名称: | Importin subunit alpha-1, Isoform 3 of Nuclear factor NF-kappa-B p105 subunit | 著者 | Smith, K.M, Tsimbalyuk, S, Aragao, D, Forwood, J.K. | 登録日 | 2021-07-14 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | MERS-CoV ORF4b employs an unusual binding mechanism to target IMP alpha and block innate immunity. Nat Commun, 13, 2022
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