PDB: 1416 件ウェブページステータス検索Chemie searchBIRD

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3UCR	Crystal structure of the immunoreceptor TIGIT IgV domain 分子名称: CHLORIDE ION, T cell immunoreceptor with Ig and ITIM domains 著者 Yin, J.P, Stengel, K.F, Rouge, L, Bazan, J.F, Wiesmann, C. 登録日 2011-10-27 公開日 2012-03-14 最終更新日 2012-04-25 実験手法 X-RAY DIFFRACTION (2.627 Å) 主引用文献 Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc.Natl.Acad.Sci.USA, 109, 2012
3UPC	A general strategy for the generation of human antibody variable domains with increased aggregation resistance 分子名称: DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... 著者 Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. 登録日 2011-11-17 公開日 2012-06-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
3UPA	A general strategy for the generation of human antibody variable domains with increased aggregation resistance 分子名称: kappa light chain variable domain 著者 Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. 登録日 2011-11-17 公開日 2012-06-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
3WV0	O-glycan attached to herpes simplex virus type 1 glycoprotein gB is recognized by the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha 分子名称: Envelope glycoprotein B, N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-galactopyranose, Paired immunoglobulin-like type 2 receptor alpha, ... 著者 Kuroki, K, Wang, J, Ose, T, Yamaguchi, M, Tabata, S, Maita, N, Nakamura, S, Kajikawa, M, Kogure, A, Satoh, T, Arase, H, Maenaka, K. 登録日 2014-05-10 公開日 2014-06-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR alpha Proc.Natl.Acad.Sci.USA, 111, 2014
3WUZ	Crystal structure of the Ig V-set domain of human paired immunoglobulin-like type 2 receptor alpha 分子名称: CITRIC ACID, ISOPROPYL ALCOHOL, Paired immunoglobulin-like type 2 receptor alpha 著者 Kuroki, K, Wang, J, Ose, T, Yamaguchi, M, Tabata, S, Maita, N, Nakamura, S, Kajikawa, M, Kogure, A, Satoh, T, Arase, H, Maenaka, K. 登録日 2014-05-10 公開日 2014-06-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR alpha Proc.Natl.Acad.Sci.USA, 111, 2014
3ZHK	The crystal structure of single domain antibody 2x1 scaffold 分子名称: MG2X1 SCAFFOLD ANTIBODY, SULFATE ION 著者 Song, H.-N, Woo, E.-J, Lim, H.-K. 登録日 2012-12-22 公開日 2014-01-08 最終更新日 2014-07-16 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter. Plos One, 9, 2014
3ZHD	The crystal structure of single domain antibody 8-4 scaffold. 分子名称: MG8-4 SCAFFOLD ANTIBODY, SULFATE ION 著者 Song, H.-N, Woo, E.-J, Lim, H.-K. 登録日 2012-12-21 公開日 2014-01-08 最終更新日 2014-07-16 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter. Plos One, 9, 2014
3ZHL	The crystal structure of single domain antibody 8-14 scaffold 分子名称: GLYCEROL, MG8-14 SCAFFOLD ANTIBODY 著者 Song, H.-N, Woo, E.-J, Lim, H.-K. 登録日 2012-12-22 公開日 2014-01-08 最終更新日 2014-07-16 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Directed Evolution of Human Heavy Chain Variable Domain (Vh) Using in Vivo Protein Fitness Filter. Plos One, 9, 2014
5F1S	Crystal structure of the teleost fish polymeric Ig receptor (pIgR) ectodomain 分子名称: polymeric Immunoglobulin Receptor 著者 Stadtmueller, B.M, Bjorkman, P.J. 登録日 2015-11-30 公開日 2016-03-16 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins. Elife, 5, 2016
5F71	Human T-cell immunoglobulin and mucin domain protein 3 (hTIM-3) 分子名称: Hepatitis A virus cellular receptor 2, SODIUM ION 著者 Gao, G.F, Lu, G, Wang, H, Qi, J. 登録日 2015-12-07 公開日 2016-02-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.404 Å) 主引用文献 Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5IR3	Crystal structure of the recombinant highest fibrillogenic natural mutant (obtained from patient AR) derived from lambda 6 light chain variable domain 分子名称: ACETATE ION, Ig lambda chain V-VI region AR 著者 Hernandez-Santoyo, A, Rodriguez-Romero, A. 登録日 2016-03-11 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Stabilizing an amyloidogenic lambda 6 light chain variable domain. FEBS J., 284, 2017
5F70	Crystal structures of human TIM members 分子名称: Hepatitis A virus cellular receptor 1 著者 Gao, G.F, Lu, G, Wang, H, Qi, J. 登録日 2015-12-07 公開日 2016-02-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors Chin.Sci.Bull., 60, 2015
5IMM	Nanobody targeting mouse Vsig4 in Spacegroup P212121 分子名称: Nanobody, Protein Vsig4 著者 Wen, Y, Zheng, F. 登録日 2016-03-06 公開日 2017-01-11 最終更新日 2017-07-05 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
5J8O	Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor 分子名称: (2R)-1-({3-bromo-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)piperidine-2-carboxylic acid, Programmed cell death 1 ligand 1 著者 Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. 登録日 2016-04-08 公開日 2016-04-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
5FFL	Crystal structure of mouse CD300lf at 1.6 Angstroms resolution. 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ... 著者 Nelson, C.A, Fremont, D.H. 登録日 2015-12-18 公開日 2016-08-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Discovery of a proteinaceous cellular receptor for a norovirus. Science, 353, 2016
5GGS	PD-1 in complex with pembrolizumab Fab 分子名称: Programmed cell death protein 1, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (1.997 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5GGT	PD-L1 in complex with BMS-936559 Fab 分子名称: IGK@ protein, IgG H chain, Programmed cell death 1 ligand 1 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
5JXE	Human PD-1 ectodomain complexed with Pembrolizumab Fab 分子名称: Pembrolizumab Fab heavy chain, Pembrolizumab Fab light chain, Programmed cell death protein 1 著者 Na, Z, Bharath, S.R, Song, H. 登録日 2016-05-13 公開日 2016-08-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab. Cell Res., 27, 2017
5GGR	PD-1 in complex with nivolumab Fab 分子名称: Programmed cell death protein 1, heavy chain, light chain 著者 Heo, Y.S. 登録日 2016-06-16 公開日 2016-11-09 最終更新日 2016-11-16 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nat Commun, 7, 2016
4Y8A	Crystal Structure of the N-terminal domain of CEACAM6 分子名称: Carcinoembryonic antigen-related cell adhesion molecule 6, GLYCEROL, ZINC ION 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2015-02-16 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Diverse oligomeric states of CEACAM IgV domains. Proc.Natl.Acad.Sci.USA, 112, 2015
4Y89	Crystal structure of the N-terminal domain of CEACAM7 分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 7 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2015-02-16 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Structure of the N-terminal dimerization domain of CEACAM7. Acta Crystallogr.,Sect.F, 71, 2015
4YIQ	Structure of the CEACAM6-CEACAM8 heterodimer 分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 6, Carcinoembryonic antigen-related cell adhesion molecule 8, ... 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2015-03-02 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Diverse oligomeric states of CEACAM IgV domains. Proc.Natl.Acad.Sci.USA, 112, 2015
5IMO	Nanobody targeting mouse Vsig4 in Spacegroup P3221 分子名称: Nanobody, Protein Vsig4 著者 Wen, Y, Zheng, F. 登録日 2016-03-06 公開日 2017-01-11 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity Immunobiology, 222, 2017
5J89	Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor 分子名称: 1,2-ETHANEDIOL, N-{2-[({2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide, Programmed cell death 1 ligand 1 著者 Zak, K.M, Grudnik, P, Guzik, K, Zieba, B.J, Musielak, B, Doemling, P, Dubin, G, Holak, T.A. 登録日 2016-04-07 公開日 2016-04-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget, 7, 2016
5JDS	Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution 分子名称: CHLORIDE ION, Nanobody, Programmed cell death 1 ligand 1, ... 著者 Zhou, A, Wei, H. 登録日 2016-04-17 公開日 2017-04-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade. Cell Discov, 3, 2017

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