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4E4V
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The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Importin subunit alpha-2
著者Hang, P.C, Miknis, Z.M, Franke, W.A, Umland, T.C, Schultz, L.W.
登録日2012-03-13
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5283 Å)
主引用文献The crystal structure of the dimeric human importin alpha 1 at 2.5 angstrom resolution.
To be Published
8TUS
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WU Polyomavirus LTA NLS bound to importin alpha 2
分子名称: Importin subunit alpha-1, Large T antigen
著者Donnelly, C.M, Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
6BVZ
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Importin alpha 3 in cargo free state
分子名称: Importin subunit alpha-3
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW9
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Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW0
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Nipah virus W protein C-terminus in complex with Importin alpha 1
分子名称: Importin subunit alpha-1, Protein W
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWB
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Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5GXW
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Importin and NuMA complex
分子名称: Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1
著者Chang, C.-C, Huang, T.-L, Hsia, K.-C.
登録日2016-09-20
公開日2017-10-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Regulation of mitotic spindle assembly factor NuMA by Importin-beta
J. Cell Biol., 216, 2017
6BVT
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Importin alpha 1 in cargo free state
分子名称: Importin subunit alpha-1
著者Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-13
公開日2018-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
1O6O
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Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form
分子名称: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1
著者Bayliss, R, Stewart, M.
登録日2002-10-10
公開日2003-10-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
5EKF
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Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 1
分子名称: DNA repair protein complementing XP-G cells, Importin subunit alpha-1
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2015-11-03
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.
J.Mol.Biol., 428, 2016
5H2W
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Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340)
分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1
著者Hirano, H, Matsuura, Y.
登録日2016-10-18
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p
J. Mol. Biol., 429, 2017
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
分子名称: Importin subunit alpha-3, Protein W
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-13
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5EKG
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BU of 5ekg by Molmil
Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2
分子名称: Importin subunit alpha-1, XPG2 peptide
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2015-11-03
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.
J.Mol.Biol., 428, 2016
5E6Q
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BU of 5e6q by Molmil
Importin alpha binding to XRCC1 NLS peptide
分子名称: CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ...
著者Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E.
登録日2015-10-10
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
Sci Rep, 5, 2015
1QZ7
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BU of 1qz7 by Molmil
Beta-catenin binding domain of Axin in complex with beta-catenin
分子名称: Axin, Beta-catenin
著者Xing, Y, Clements, W.K, Kimelman, D, Xu, W.
登録日2003-09-15
公開日2003-11-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex
GENES DEV., 17, 2003
6BWA
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BU of 6bwa by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
1O6P
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Importin Beta bound to a GLFG Nucleoporin peptide
分子名称: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE
著者Bayliss, R, Stewart, M.
登録日2002-10-10
公開日2003-04-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
6BW1
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BU of 6bw1 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 1
分子名称: Importin subunit alpha-1, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5H43
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Structural and mechanistical studies of the nuclear import by Importin-alpha
分子名称: Histone acetyltransferase KAT8, Importin subunit alpha-1
著者Wang, R, Li, Y.
登録日2016-10-28
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Traffic, 19, 2018
6D7N
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BU of 6d7n by Molmil
Crystal structure of the W357R/W399R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
1Q1S
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Mouse Importin alpha- phosphorylated SV40 CN peptide complex
分子名称: Importin alpha-2 subunit, Large T antigen
著者Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
登録日2003-07-22
公開日2004-03-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1T
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BU of 1q1t by Molmil
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
分子名称: Importin alpha-2 subunit, Large T antigen
著者Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
登録日2003-07-22
公開日2004-03-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
5HHG
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Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex
分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5
著者Smith, K.M, Forwood, J.K.
登録日2016-01-11
公開日2016-05-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog., 12, 2016
1EJY
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MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, NUCLEOPLASMIN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-05
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
7L04
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Crystal Structure of Adeno-Associated Virus Porcine Origin capsid protein in complex with Importin-alpha 2
分子名称: Importin subunit alpha-1, VP1
著者Hoad, M, Forwood, J.
登録日2020-12-11
公開日2021-02-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structure of Adeno-Associated Virus Porcine Origin capsid protein in complex with Importin-alpha 2
To Be Published

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