5H1Y
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5SUQ
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![BU of 5suq by Molmil](/molmil-images/mine/5suq) | Crystal structure of the THO-Sub2 complex | 分子名称: | 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ... | 著者 | Ren, Y, Blobel, G. | 登録日 | 2016-08-03 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (6 Å) | 主引用文献 | Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
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5SUP
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![BU of 5sup by Molmil](/molmil-images/mine/5sup) | Crystal structure of the Sub2-Yra1 complex in association with RNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ... | 著者 | Ren, Y, Schmiege, P, Blobel, G. | 登録日 | 2016-08-03 | 公開日 | 2017-01-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
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5WSG
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![BU of 5wsg by Molmil](/molmil-images/mine/5wsg) | Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution | 分子名称: | 3'-exon-intron, 3'-intron-lariat, 5'-exon, ... | 著者 | Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. | 登録日 | 2016-12-07 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of a yeast step II catalytically activated spliceosome Science, 355, 2017
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5LTA
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5LTK
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5LTJ
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![BU of 5ltj by Molmil](/molmil-images/mine/5ltj) | Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Tauchert, M.J, Ficner, R. | 登録日 | 2016-09-06 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. Elife, 6, 2017
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5I8Q
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![BU of 5i8q by Molmil](/molmil-images/mine/5i8q) | S. cerevisiae Prp43 in complex with RNA and ADPNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ... | 著者 | He, Y, Nielsen, K.H, Andersen, G.R. | 登録日 | 2016-02-19 | 公開日 | 2017-02-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA. RNA, 23, 2017
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5JPT
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![BU of 5jpt by Molmil](/molmil-images/mine/5jpt) | CRYSTAL STRUCTURE OF THE PRP43P DEAH-BOX RNA HELICASE IN COMPLEX WITH CDP | 分子名称: | ACETATE ION, CYTIDINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Robert-Paganin, J, Rety, S, Leulliot, N. | 登録日 | 2016-05-04 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.935 Å) | 主引用文献 | Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding. Nucleic Acids Res., 45, 2017
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5MQF
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![BU of 5mqf by Molmil](/molmil-images/mine/5mqf) | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
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5GJU
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![BU of 5gju by Molmil](/molmil-images/mine/5gju) | DEAD-box RNA helicase | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD | 著者 | Xu, L, Li, F, Wang, L, Shi, Y. | 登録日 | 2016-07-02 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions. Structure, 25, 2017
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5NRL
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![BU of 5nrl by Molmil](/molmil-images/mine/5nrl) | Structure of a pre-catalytic spliceosome. | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | 登録日 | 2017-04-24 | 公開日 | 2017-05-31 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Structure of a pre-catalytic spliceosome. Nature, 546, 2017
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5XDR
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![BU of 5xdr by Molmil](/molmil-images/mine/5xdr) | Crystal structure of human DEAH-box RNA helicase DHX15 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15, ... | 著者 | Murakami, K, Nakano, K, Shimizu, T, Ohto, U. | 登録日 | 2017-03-29 | 公開日 | 2017-06-21 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of human DEAH-box RNA helicase 15 reveals a domain organization of the mammalian DEAH/RHA family Acta Crystallogr F Struct Biol Commun, 73, 2017
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5XJC
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![BU of 5xjc by Molmil](/molmil-images/mine/5xjc) | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | 登録日 | 2017-04-30 | 公開日 | 2017-07-05 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
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5LST
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5URM
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![BU of 5urm by Molmil](/molmil-images/mine/5urm) | Crystal structure of human BRR2 in complex with T-1206548 | 分子名称: | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Klein, M.G, Tjhen, R, Qin, L. | 登録日 | 2017-02-11 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5URJ
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![BU of 5urj by Molmil](/molmil-images/mine/5urj) | Crystal structure of human BRR2 in complex with T-3905516 | 分子名称: | 6-benzyl-3-[(2R)-2-(3-fluoropyridin-2-yl)-6-methyl-3,4-dihydro-2H-1-benzopyran-7-yl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(3H,8H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Klein, M.G, Tjhen, R, Qin, L. | 登録日 | 2017-02-10 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5URK
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![BU of 5urk by Molmil](/molmil-images/mine/5urk) | Crystal structure of human BRR2 in complex with T-3935799 | 分子名称: | 6-benzyl-3-[3-(benzyloxy)phenyl]-4,6-dihydropyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione, GLYCEROL, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Qin, L, Tjhen, R, Klein, M.G. | 登録日 | 2017-02-10 | 公開日 | 2017-07-19 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J. Med. Chem., 60, 2017
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5O9Z
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5OOQ
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![BU of 5ooq by Molmil](/molmil-images/mine/5ooq) | Structure of the Mtr4 Nop53 Complex | 分子名称: | ATP-dependent RNA helicase DOB1, Ribosome biogenesis protein NOP53, SULFATE ION | 著者 | Falk, S, Basquin, J, Conti, E. | 登録日 | 2017-08-08 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the interaction of the nuclear exosome helicase Mtr4 with the preribosomal protein Nop53. RNA, 23, 2017
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5V9X
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![BU of 5v9x by Molmil](/molmil-images/mine/5v9x) | Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP | 分子名称: | ATP-dependent DNA helicase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Ordonez, H, Jacewicz, A, Ferrao, R, Shuman, S. | 登録日 | 2017-03-23 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | 主引用文献 | Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases. Nucleic Acids Res., 46, 2018
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6BU9
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![BU of 6bu9 by Molmil](/molmil-images/mine/6bu9) | Drosophila Dicer-2 bound to blunt dsRNA | 分子名称: | Dicer-2, isoform A, RNA (5'-R(*AP*CP*UP*AP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*UP*AP*C)-3'), ... | 著者 | Shen, P.S, Sinha, N.K, Bass, B.L. | 登録日 | 2017-12-09 | 公開日 | 2017-12-27 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Dicer uses distinct modules for recognizing dsRNA termini. Science, 359, 2018
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6EM3
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![BU of 6em3 by Molmil](/molmil-images/mine/6em3) | State A architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6EM4
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![BU of 6em4 by Molmil](/molmil-images/mine/6em4) | State B architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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6EM5
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![BU of 6em5 by Molmil](/molmil-images/mine/6em5) | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | 分子名称: | 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 25S ribosomal RNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... | 著者 | Kater, L, Cheng, J, Barrio-Garcia, C, Hurt, E, Beckmann, R. | 登録日 | 2017-10-01 | 公開日 | 2017-12-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
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