PDB: 294 件ウェブページステータス検索Chemie searchBIRD

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5W2P	Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... 著者 Capodagli, G.C, Neiditch, M.B. 登録日 2017-06-06 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. MBio, 9, 2018
5W2Q	Crystal structure of Mycobacterium tuberculosis KasA in complex with 6U5 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, GLYCEROL, ... 著者 Capodagli, G.C, Neiditch, M.B. 登録日 2017-06-06 公開日 2018-12-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA. MBio, 9, 2018
6C9U	Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab) 分子名称: 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ... 著者 Deis, L.N, Li, X, Mathews, I.I, Khosla, C. 登録日 2018-01-28 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module. J. Am. Chem. Soc., 140, 2018
6FIJ	Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... 著者 Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T. 登録日 2018-01-18 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
6FIK	ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS 分子名称: Polyketide synthase 著者 Herbst, D.A, Huitt-Roehl, C.R, Jakob, R.P, Townsend, C.A, Maier, T. 登録日 2018-01-18 公開日 2018-03-21 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
5MY2	KS-MAT DI-DOMAIN OF MOUSE FAS 分子名称: COENZYME A, Fatty acid synthase 著者 Paithankar, K.S, Rittner, A, Vu Huu, K, Grininger, M. 登録日 2017-01-25 公開日 2018-02-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 KS-MAT DI-DOMAIN OF MOUSE FAS To Be Published
5KOF	Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and Acyl Carrier Protein, AcpP 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(prop-2-enoylamino)ethylamino]propyl]amino]butyl] dihydrogen phosphate 著者 Milligan, J.C, Jackson, D.R, Barajas, J.F, Tsai, S.C. 登録日 2016-06-30 公開日 2018-01-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nat.Chem.Biol., 15, 2019
5MY0	KS-MAT DI-DOMAIN OF MOUSE FAS WITH MALONYL-COA 分子名称: COENZYME A, Fatty acid synthase, MALONYL-COENZYME A 著者 Paithankar, K.S, Rittner, A, Huu, K.V, Grininger, M. 登録日 2017-01-25 公開日 2018-01-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Characterization of the Polyspecific Transferase of Murine Type I Fatty Acid Synthase (FAS) and Implications for Polyketide Synthase (PKS) Engineering. ACS Chem. Biol., 13, 2018
5SXO	1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Soares da Costa, T.P, Nanson, J.D, Forwood, J.K. 登録日 2016-08-09 公開日 2016-11-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes To Be Published
5LD8	GSK3011724A cocrystallised with Mycobacterium tuberculosis H37Rv KasA 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 1, SODIUM ION, TETRAETHYLENE GLYCOL, ... 著者 Chung, C.W, Neu, M. 登録日 2016-06-23 公開日 2016-09-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Identification of KasA as the cellular target of an anti-tubercular scaffold. Nat Commun, 7, 2016
4Z37	Structure of the ketosynthase of module 2 of C0ZGQ5 (trans-AT PKS) from Brevibacillus brevis 分子名称: Putative mixed polyketide synthase/non-ribosomal peptide synthetase 著者 Martin, S.F, Jakob, R.P, Herbst, D.A, Maier, T. 登録日 2015-03-31 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 The structural organization of trans-AT polyketide synthases: ketoacyl synthase and trans-acting enoyl reductase To Be Published
5BP1	Condensing di-domain (KS-AT) of a mycocerosic acid synthase-like (MAS-like) PKS 分子名称: Mycocerosic acid synthase 著者 Jakob, R.P, Herbst, D.A, Zaehringer, F, Maier, T. 登録日 2015-05-27 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases. Nature, 531, 2016
5ELP	Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 分子名称: NRPS/PKS protein 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Zogzas, C.E. 登録日 2015-11-04 公開日 2016-01-13 最終更新日 2016-11-02 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERF	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 分子名称: Polyketide synthase PksL 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. 登録日 2015-11-14 公開日 2015-12-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERB	Ketosynthase from module 5 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 分子名称: Polyketide synthase 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Meinke, J. 登録日 2015-11-13 公開日 2015-12-23 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ENY	Ketosynthase from module 6 connected to acyl carrier protein from module 5 (unobservable) of the bacillaene synthase from Bacillus subtilis 168 分子名称: Polyketide synthase PksL 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. 登録日 2015-11-09 公開日 2015-12-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5E5N	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 1) 分子名称: Polyketide synthase PksL 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. 登録日 2015-10-08 公開日 2015-11-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5E6K	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 2) 分子名称: Polyketide synthase PksL, SULFATE ION 著者 Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. 登録日 2015-10-10 公開日 2015-11-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
4ZDN	Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS4 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION 著者 Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2015-04-17 公開日 2015-05-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.509 Å) 主引用文献 Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
4XOX	Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae 分子名称: 3-oxoacyl-ACP synthase 著者 Hou, J, Grabowski, M, Cymborowski, M, Zheng, H, Cooper, D.R, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-01-16 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structure of beta-ketoacyl-ACP synthase I (FabB) from Vibrio Cholerae to be published
4R8E	Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Yersinia pestis 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Himiari, Z, Nanson, J.D, Swarbrick, C.M.D, Forwood, J.K. 登録日 2014-09-02 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis. Sci Rep, 5, 2015
4CW4	Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa 分子名称: BETA-KETOACYL SYNTHASE, CHLORIDE ION, SULFATE ION 著者 Bukhari, H.S.T, Jakob, R.P, Maier, T. 登録日 2014-04-01 公開日 2014-12-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.349 Å) 主引用文献 Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase. Structure, 22, 2014
4WKY	Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmN KS2 分子名称: 1,2-ETHANEDIOL, Beta-ketoacyl synthase, GLYCEROL, ... 著者 Cuff, M.E, Mack, J.C, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2014-10-03 公開日 2014-10-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
4QYR	Streptomyces platensis isomigrastatin ketosynthase domain MgsE KS3 分子名称: ACETIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... 著者 Kim, Y, Li, H, Endres, M, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2014-07-25 公開日 2014-08-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
4V8L	Cryo-EM Structure of the Mycobacterial Fatty Acid Synthase 分子名称: FATTY ACID SYNTHASE, FLAVIN MONONUCLEOTIDE 著者 Boehringer, D, Ban, N, Leibundgut, M. 登録日 2012-12-06 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.5 Å) 主引用文献 7.5-A Cryo-Em Structure of the Mycobacterial Fatty Acid Synthase. J.Mol.Biol., 425, 2013

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