PDB: 48855 件ウェブページステータス検索Chemie searchBIRD

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6NY1	CasX-gRNA-DNA(30bp) State II 分子名称: CasX, DNA Non-target strand, DNA target strand, ... 著者 Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. 登録日 2019-02-10 公開日 2019-02-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566, 2019
5NO6	TEAD4-HOXB13 complex bound to DNA 分子名称: DNA, Homeobox protein Hox-B13, Transcriptional enhancer factor TEF-3 著者 Morgunova, E, Jolma, A, Yin, Y, Popov, A, Taipale, J. 登録日 2017-04-11 公開日 2018-05-16 最終更新日 2025-04-23 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 DNA-guided transcription factor interactions extend human gene regulatory code. Nature, 2025
5GZB	Crystal Structure of Transcription Factor TEAD4 in Complex with M-CAT DNA 分子名称: DNA (5'-D(*GP*AP*GP*AP*GP*GP*AP*AP*TP*GP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*CP*AP*TP*TP*CP*CP*TP*CP*TP*C)-3'), GLYCEROL, ... 著者 He, F, Shi, Z.B, Zhou, Z.C. 登録日 2016-09-28 公開日 2017-04-19 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 DNA-binding mechanism of the Hippo pathway transcription factor TEAD4 Oncogene, 36, 2017
5BNG	monomer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA 分子名称: DNA (5'-D(P*AP*AP*TP*TP*AP*GP*CP*TP*GP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A-3'), ... 著者 Morgunova, E, Jolma, A, Yin, Y, Nitta, K, Dave, K, Popov, A, Taipale, M, Enge, M, Kivioja, T, Taipale, J. 登録日 2015-05-26 公開日 2015-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature, 527, 2015
4WK8	FOXP3 forms a domain-swapped dimer to bridge DNA 分子名称: DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), Forkhead box protein P3 著者 Chen, Y, Chen, L. 登録日 2014-10-01 公開日 2015-01-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4006 Å) 主引用文献 DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Nucleic Acids Res., 43, 2015
1D66	DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX 分子名称: CADMIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), ... 著者 Marmorstein, R, Carey, M, Ptashne, M, Harrison, S.C. 登録日 1992-03-06 公開日 1992-03-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 DNA recognition by GAL4: structure of a protein-DNA complex. Nature, 356, 1992
4IEM	Human apurinic/apyrimidinic endonuclease (APE1) with product DNA and Mg2+ 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*C)-3'), DNA (5'-D(P*(3DR)P*GP*AP*TP*CP*G)-3'), ... 著者 Tsutakawa, S.E, Mol, C.D, Arvai, A.S, Tainer, J.A. 登録日 2012-12-13 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3936 Å) 主引用文献 Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes. J.Biol.Chem., 288, 2013
8OSB	TWIST1-TCF4-ALX4 complex on specific DNA 分子名称: DNA (25-MER), Homeobox protein aristaless-like 4, Transcription factor 4, ... 著者 Morgunova, E, Kim, S, Popov, A, Wysocka, J, Taipale, J. 登録日 2023-04-18 公開日 2024-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 DNA-guided transcription factor cooperativity shapes face and limb mesenchyme. Cell, 187, 2024
1J1V	Crystal structure of DnaA domainIV complexed with DnaAbox DNA 分子名称: 5'-D(*CP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*A)-3', 5'-D(*TP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*G)-3', Chromosomal replication initiator protein dnaA 著者 Fujikawa, N, Kurumizaka, H, Nureki, O, Terada, T, Shirouzu, M, Katayama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2002-12-18 公開日 2003-04-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of replication origin recognition by the DnaA protein NUCLEIC ACIDS RES., 31, 2003
110D	ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL 分子名称: DAUNOMYCIN, DNA (5'-D(*CP*GP*GP*CP*CP*G)-3') 著者 Leonard, G.A, Hambley, T.W, McAuley-Hecht, K, Brown, T, Hunter, W.N. 登録日 1993-01-21 公開日 1993-04-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes. Acta Crystallogr.,Sect.D, 49, 1993
1A73	INTRON-ENCODED ENDONUCLEASE I-PPOI COMPLEXED WITH DNA 分子名称: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*A)-3'), DNA (5'-D(P*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON 3 (I-PPO) ENCODED ENDONUCLEASE, ... 著者 Flick, K.E, Monnat Junior, R.J, Stoddard, B.L. 登録日 1998-03-19 公開日 1998-10-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature, 394, 1998
4Z3C	Zinc finger region of human TET3 in complex with CpG DNA 分子名称: DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase, UNKNOWN ATOM OR ION, ... 著者 Liu, K, Xu, C, Tempel, W, Dong, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-03-31 公開日 2015-04-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 2017
1A74	I-PPOL HOMING ENDONUCLEASE/DNA COMPLEX 分子名称: DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*A P*GP*TP*CP*A)-3'), INTRON-ENCODED ENDONUCLEASE I-PPOI, ZINC ION 著者 Jurica, B.L, Flick, K.E, Monnat Junior, R.J, Stoddard, M.S. 登録日 1998-03-19 公開日 1998-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature, 394, 1998
5C53	Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma 分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... 著者 Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. 登録日 2015-06-19 公開日 2016-01-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.567 Å) 主引用文献 Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
5YUR	DNA polymerase IV - DNA ternary complex 1 分子名称: DNA polymerase IV, DTN, SODIUM ION, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.035 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
154D	DNA DISTORTION IN BIS-INTERCALATED COMPLEXES 分子名称: BIS-(N-ETHYLPYRIDINIUM-(3-METHOXYCARBAZOLE))HEXANE-1,6-DIAMINE, DNA (5'-D(*(CBR)P*GP*CP*G)-3') 著者 Peek, M.E, Lipscomb, L.A, Bertrand, J.A, Gao, Q, Roques, B.P, Garbay-Jaureguiberry, C, Williams, L.D. 登録日 1993-12-14 公開日 1994-08-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 DNA distortion in bis-intercalated complexes. Biochemistry, 33, 1994
5YUT	DNA polymerase IV - DNA ternary complex 3 分子名称: DNA polymerase IV, DTN, MAGNESIUM ION, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-09-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
5YUU	DNA polymerase IV - DNA ternary complex 4 分子名称: DNA polymerase IV, DTN1, DTN2, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2019-01-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.892 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
5YUS	DNA polymerase IV - DNA ternary complex 2 分子名称: DNA polymerase IV, DTN, MAGNESIUM ION, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-11-07 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
5YUV	DNA polymerase IV - DNA ternary complex 5 分子名称: DNA polymerase IV, DTN1, DTN2, ... 著者 Kottur, J, Nair, D.T. 登録日 2017-11-23 公開日 2018-10-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction Nucleic Acids Res., 46, 2018
4PZI	Zinc finger region of MLL2 in complex with CpG DNA 分子名称: DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), Histone-lysine N-methyltransferase 2B, UNKNOWN ATOM OR ION, ... 著者 Chao, X, Tempel, W, Liu, K, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2014-03-31 公開日 2014-06-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 26, 2018
3BDP	DNA POLYMERASE I/DNA COMPLEX 分子名称: DNA (5'-D(*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*CP*2DT)-3'), PROTEIN (DNA POLYMERASE I), ... 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1997-11-17 公開日 1999-01-13 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
2Z4S	Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosomal replication initiator protein dnaA, MAGNESIUM ION 著者 Fujikawa, N, Ozaki, S, Kagawa, W, Park, S.-Y, Katayama, T, Kurumizaka, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-06-25 公開日 2008-02-19 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Common Mechanism for the ATP-DnaA-dependent Formation of Open Complexes at the Replication Origin. J.Biol.Chem., 283, 2008
3G9O	GR DNA-binding domain:Sgk 16bp complex-9 分子名称: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Pufall, M.A, Yamamoto, K.R, Meijsing, S.H. 登録日 2009-02-13 公開日 2009-04-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 DNA binding site sequence directs glucocorticoid receptor structure and activity. Science, 324, 2009
6GN4	tc-DNA/tc-DNA duplex 分子名称: Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), Tc-DNA (5'-D(*(TCS)P*(TTK)P*(TCY)P*(TCY)P*(TCS)P*(TCJ)P*(TCJ)P*(TCS)P*(TCY)P*(TCS))-3') 著者 Istrate, A, Johannsen, S, Istrate, A, Sigel, R.K.O, Leumann, C. 登録日 2018-05-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. Nucleic Acids Res., 47, 2019

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