4PZI
Zinc finger region of MLL2 in complex with CpG DNA
Summary for 4PZI
Entry DOI | 10.2210/pdb4pzi/pdb |
Descriptor | Histone-lysine N-methyltransferase 2B, DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc finger, dna-binding, structural genomics, structural genomics consortium, sgc, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9UMN6 |
Total number of polymer chains | 3 |
Total formula weight | 15022.70 |
Authors | Chao, X.,Tempel, W.,Liu, K.,Dong, A.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2014-03-31, release date: 2014-06-04, Last modification date: 2024-04-03) |
Primary citation | Xu, C.,Liu, K.,Lei, M.,Yang, A.,Li, Y.,Hughes, T.R.,Min, J. DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 26:85-95.e3, 2018 Cited by PubMed: 29276034DOI: 10.1016/j.str.2017.11.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report