6GN4

tc-DNA/tc-DNA duplex

Summary for 6GN4

• Entry DOI: 10.2210/pdb6gn4/pdb
• Related: 6GMY
• NMR Information: BMRB: 34277
• Descriptor: Tc-DNA (5'-D(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3'), Tc-DNA (5'-D(*(TCS)P*(TTK)P*(TCY)P*(TCY)P*(TCS)P*(TCJ)P*(TCJ)P*(TCS)P*(TCY)P*(TCS))-3') (2 entities in total)
• Functional Keywords: tricyclo-dna, modified nucleic acids, modified oligonucleotide, tc-dna, dna
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 6775.17

Authors

Istrate, A.,Johannsen, S.,Istrate, A.,Sigel, R.K.O.,Leumann, C. (deposition date: 2018-05-29, release date: 2018-06-06, Last modification date: 2019-05-22)

• Primary citation: Istrate, A.,Johannsen, S.,Istrate, A.,Sigel, R.K.O.,Leumann, C.J.; NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance.; Nucleic Acids Res., 47:4872-4882, 2019; PubMed: 30916334; DOI: 10.1093/nar/gkz197

Experimental method

SOLUTION NMR