6TO9
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7ZH4
| USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement) | 分子名称: | 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ... | 著者 | Rennie, M.L, Walden, H. | 登録日 | 2022-04-05 | 公開日 | 2022-10-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
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5XNS
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4NRI
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4N1U
| Structure of human MTH1 in complex with TH588 | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, N~4~-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine, SULFATE ION | 著者 | Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. | 登録日 | 2013-10-04 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
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1PVO
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3S1S
| Characterization and crystal structure of the type IIG restriction endonuclease BpuSI | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, MANGANESE (II) ION, ... | 著者 | Shen, B.W, Xu, D, Chan, S.-H, Zheng, Y, Zhu, Y, Xu, S.-Y, Stoddard, B.L. | 登録日 | 2011-05-16 | 公開日 | 2011-07-13 | 最終更新日 | 2011-10-19 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI. Nucleic Acids Res., 39, 2011
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1D8B
| NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE | 分子名称: | SGS1 RECQ HELICASE | 著者 | Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M. | 登録日 | 1999-10-21 | 公開日 | 2000-01-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins. Structure Fold.Des., 7, 1999
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1UST
| YEAST HISTONE H1 GLOBULAR DOMAIN I, HHO1P GI, SOLUTION NMR STRUCTURES | 分子名称: | HISTONE H1 | 著者 | Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O. | 登録日 | 2003-11-30 | 公開日 | 2004-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P J.Mol.Biol., 338, 2004
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3PLW
| Ref protein from P1 bacteriophage | 分子名称: | Recombination enhancement function protein, SULFATE ION, ZINC ION | 著者 | Keck, J.L, Lu, D, Cox, M.M. | 登録日 | 2010-11-15 | 公開日 | 2010-12-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Creating Directed Double-strand Breaks with the Ref Protein: A NOVEL RecA-DEPENDENT NUCLEASE FROM BACTERIOPHAGE P1. J.Biol.Chem., 286, 2011
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1USS
| YEAST HISTONE H1 GLOBULAR DOMAIN II, HHO1P GII, SOLUTION NMR STRUCTURES | 分子名称: | HISTONE H1 | 著者 | Ali, T, Coles, P, Stevens, T.J, Stott, K, Thomas, J.O. | 登録日 | 2003-11-30 | 公開日 | 2004-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Two Homologous Domains of Similar Structure But Different Stability in the Yeast Linker Histone, Hho1P J.Mol.Biol., 338, 2004
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3DOM
| Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | 分子名称: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | 著者 | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | 登録日 | 2008-07-04 | 公開日 | 2008-08-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for group A trichothiodystrophy Nat.Struct.Mol.Biol., 15, 2008
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2WMM
| Crystal structure of the hinge domain of MukB | 分子名称: | Chromosome partition protein MukB, D-MALATE | 著者 | Ku, B, Oh, B.-H. | 登録日 | 2009-07-01 | 公開日 | 2010-01-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the MukB hinge domain with coiled-coil stretches and its functional implications. Proteins, 78, 2010
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5VF0
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1LJP
| Crystal Structure of beta-Cinnamomin Elicitin | 分子名称: | Beta-elicitin cinnamomin | 著者 | Rodrigues, M.L, Archer, M, Martel, P, Jacquet, A, Cravador, A, Carrondo, M.A. | 登録日 | 2002-04-22 | 公開日 | 2002-07-31 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of beta-cinnamomin, a protein toxic to some plant species. Acta Crystallogr.,Sect.D, 58, 2002
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1LWE
| CRYSTAL STRUCTURE OF M41L/T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMN) IN COMPLEX WITH NEVIRAPINE | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | 登録日 | 2002-05-31 | 公開日 | 2002-10-30 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. J.Virol., 76, 2002
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1LWC
| CRYSTAL STRUCTURE OF M184V MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | 著者 | Ren, J, Chamberlain, P.P, Nichols, C.E, Douglas, L, Stuart, D.I, Stammers, D.K. | 登録日 | 2002-05-31 | 公開日 | 2002-10-30 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215. J.Virol., 76, 2002
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1N1Q
| Crystal structure of a Dps protein from Bacillus brevis | 分子名称: | DPS Protein, MU-OXO-DIIRON | 著者 | Ren, B, Tibbelin, G, Kajino, T, Asami, O, Ladenstein, R. | 登録日 | 2002-10-19 | 公開日 | 2003-05-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Multi-layered Structure of Dps with a Novel Di-nuclear Ferroxidase Center J.Mol.Biol., 329, 2003
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5LMF
| Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM3 peptide (region 484-500) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ... | 著者 | Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M. | 登録日 | 2016-07-30 | 公開日 | 2017-08-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MEC
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5MEA
| Crystal structure of yeast Cdt1 (N terminal and middle domain), form 2. | 分子名称: | Cell division cycle protein CDT1, GLYCEROL, SULFATE ION | 著者 | Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. | 登録日 | 2016-11-14 | 公開日 | 2017-05-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
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5MEB
| Crystal structure of yeast Cdt1 C-terminal domain | 分子名称: | Cell division cycle protein CDT1, SULFATE ION | 著者 | Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. | 登録日 | 2016-11-14 | 公開日 | 2017-05-17 | 最終更新日 | 2017-07-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
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2M1G
| Parallel human telomeric quadruplex containing 2'F-ANA substitutions | 分子名称: | 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(GFL)P*GP*GP*T)-3' | 著者 | Martin-Pintado, N, Yahyaee-Anzahaee, M, Deleavey, G.F, Portella, G, Orozco, M, Damha, M.J, Gonzalez, C. | 登録日 | 2012-11-27 | 公開日 | 2013-05-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom. J.Am.Chem.Soc., 135, 2013
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5ME9
| Crystal structure of yeast Cdt1 (N terminal and middle domain), form 1. | 分子名称: | Cell division cycle protein CDT1, GLYCEROL, SULFATE ION | 著者 | Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. | 登録日 | 2016-11-14 | 公開日 | 2017-05-17 | 最終更新日 | 2017-07-05 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
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6Q1H
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