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7O4R
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BU of 7o4r by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the thiolase active sites and additional binding site (CoA(HAD/KAT))
分子名称: 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
1ZL5
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BU of 1zl5 by Molmil
Crystal structure of Glu335Gln mutant of Clostridium botulinum neurotoxin E catalytic domain
分子名称: CHLORIDE ION, botulinum neurotoxin type E
著者Agarwal, R, Binz, T, Swaminathan, S.
登録日2005-05-05
公開日2005-07-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Analysis of Active Site Residues of Botulinum Neurotoxin E by Mutational, Functional, and Structural Studies: Glu335Gln Is an Apoenzyme.
Biochemistry, 44, 2005
2E9X
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BU of 2e9x by Molmil
The crystal structure of human GINS core complex
分子名称: DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ...
著者Kamada, K, Hanaoka, F.
登録日2007-01-27
公開日2007-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the human GINS complex and its assembly and functional interface in replication initiation
Nat.Struct.Mol.Biol., 14, 2007
3HNK
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BU of 3hnk by Molmil
Crystal structure of the dimeric assembly of the cyt cb562 variant RIDC-1
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562
著者Salgado, E.N, Lewis, R.A, Brodin, J, Tezcan, F.A.
登録日2009-05-31
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Metal templated design of protein interfaces.
Proc.Natl.Acad.Sci.USA, 107, 2010
7A0L
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BU of 7a0l by Molmil
Joint neutron/X-ray room temperature structure of perdeuterated Aspergillus flavus urate oxidase in complex with the 8-azaxanthine inhibitor and catalytic water bound in the peroxo hole
分子名称: 8-AZAXANTHINE, SODIUM ION, Uricase
著者McGregor, L, Bui, S, Blakeley, M.P, Steiner, R.A.
登録日2020-08-09
公開日2020-12-09
最終更新日2024-05-01
実験手法NEUTRON DIFFRACTION (1.33 Å), X-RAY DIFFRACTION
主引用文献Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis.
Iucrj, 8, 2021
5VBX
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BU of 5vbx by Molmil
Crystal structure of holo-[acyl-carrier-protein] synthase (AcpS) from Escherichia coli
分子名称: 1,2-ETHANEDIOL, Holo-[acyl-carrier-protein] synthase, SODIUM ION
著者Marcella, A.M, Barb, A.W.
登録日2017-03-30
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex.
J. Mol. Biol., 429, 2017
5VCF
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BU of 5vcf by Molmil
RNA hairpin structure containing tetraloop/receptor motif, complexed with 2-MeImpG analogue
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*CP*CP*GP*AP*AP*AP*GP*G)-3')
著者Zhang, W, Szostak, J.W.
登録日2017-03-31
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5X5I
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BU of 5x5i by Molmil
The X-ray crystal structure of a TetR family transcription regulator RcdA involved in the regulation of biofilm formation in Escherichia coli
分子名称: HTH-type transcriptional regulator RcdA
著者Sugino, H, Usui, M, Shimada, T, Nakano, M, Ogasawara, H, Ishihama, A, Hirata, A.
登録日2017-02-16
公開日2017-12-27
実験手法X-RAY DIFFRACTION (2.554 Å)
主引用文献A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation.
FEBS Lett., 591, 2017
1CX9
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BU of 1cx9 by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID
分子名称: 4-(2-AMINOPHENYLTHIO)-BUTYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E.
登録日1999-08-29
公開日1999-12-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase.
Biochemistry, 38, 1999
1D9E
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BU of 1d9e by Molmil
STRUCTURE OF E. COLI KDO8P SYNTHASE
分子名称: 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE, SULFATE ION
著者Radaev, S, Dastidar, P, Patel, M, Woodard, R.W, Gatti, D.L.
登録日1999-10-27
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and mechanism of 3-deoxy-D-manno-octulosonate 8-phosphate synthase.
J.Biol.Chem., 275, 2000
1CJX
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BU of 1cjx by Molmil
CRYSTAL STRUCTURE OF PSEUDOMONAS FLUORESCENS HPPD
分子名称: 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE, ACETATE ION, ETHYL MERCURY ION, ...
著者Serre, L, Sailland, A, Sy, D, Boudec, P, Rolland, A, Pebay-Peroulla, E, Cohen-Addad, C.
登録日1999-04-20
公開日2000-04-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Pseudomonas fluorescens 4-hydroxyphenylpyruvate dioxygenase: an enzyme involved in the tyrosine degradation pathway.
Structure Fold.Des., 7, 1999
1CMX
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BU of 1cmx by Molmil
STRUCTURAL BASIS FOR THE SPECIFICITY OF UBIQUITIN C-TERMINAL HYDROLASES
分子名称: PROTEIN (UBIQUITIN YUH1-UBAL)
著者Johnston, S.C, Riddle, S.M, Cohen, R.E, Hill, C.P.
登録日1999-05-12
公開日1999-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for the specificity of ubiquitin C-terminal hydrolases.
EMBO J., 18, 1999
2AXU
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BU of 2axu by Molmil
Structure of PrgX
分子名称: PrgX
著者Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.K, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A.
登録日2005-09-06
公開日2005-12-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.
Proc.Natl.Acad.Sci.Usa, 102, 2005
7AOI
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BU of 7aoi by Molmil
Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate
分子名称: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ...
著者Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A.
登録日2020-10-14
公開日2020-12-02
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Embo J., 40, 2021
5OPH
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BU of 5oph by Molmil
G-quadruplex structure of DNA oligonucleotide containing GGGGCC repeats linked to ALS and FTD
分子名称: DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*CP*GP*GP*(BGM)P*G)-3')
著者Brcic, J, Plavec, J.
登録日2017-08-09
公開日2018-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism.
Nucleic Acids Res., 46, 2018
1APZ
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BU of 1apz by Molmil
HUMAN ASPARTYLGLUCOSAMINIDASE COMPLEX WITH REACTION PRODUCT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC ACID, ASPARTYLGLUCOSAMINIDASE, ...
著者Rouvinen, J, Oinonen, C.
登録日1995-06-14
公開日1996-12-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of human lysosomal aspartylglucosaminidase.
Nat.Struct.Biol., 2, 1995
7CD0
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BU of 7cd0 by Molmil
Crystal structure of the 2-iodoporphobilinogen-bound ES2 intermediate form of human hydroxymethylbilane synthase
分子名称: 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
著者Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
登録日2020-06-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
7CCZ
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BU of 7ccz by Molmil
Crystal structure of the ES2 intermediate form of human hydroxymethylbilane synthase
分子名称: 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
著者Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
登録日2020-06-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
7CCX
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BU of 7ccx by Molmil
Crystal structure of the holo form of human hydroxymethylbilane synthase
分子名称: 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
著者Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
登録日2020-06-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
1ZZJ
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BU of 1zzj by Molmil
Structure of the third KH domain of hnRNP K in complex with 15-mer ssDNA
分子名称: 5'-D(*TP*TP*CP*CP*CP*CP*TP*CP*CP*CP*CP*AP*TP*TP*T)-3', Heterogeneous nuclear ribonucleoprotein K
著者Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S.
登録日2005-06-14
公開日2005-08-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
7CCY
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BU of 7ccy by Molmil
Crystal structure of the 2-iodoporphobilinogen-bound holo form of human hydroxymethylbilane synthase
分子名称: 3-[5-(aminomethyl)-4-(carboxymethyl)-2-iodo-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase
著者Sato, H, Sugishima, M, Wada, K, Hirabayashi, K, Tsukaguchi, M.
登録日2020-06-18
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Biochem.J., 478, 2021
6HOF
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BU of 6hof by Molmil
TRANSCRIPTIONAL REPRESSOR ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH BDM44852
分子名称: 4-[2-(phenylsulfonylaminomethyl)-1,3-thiazol-4-yl]-~{N}-[3,3,3-tris(fluoranyl)propyl]benzamide, HTH-type transcriptional regulator EthR
著者Wintjens, R, Wohlkonig, A.
登録日2018-09-17
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
Biochim Biophys Acta Proteins Proteom, 1867, 2018
6RL2
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BU of 6rl2 by Molmil
The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotetraose
分子名称: Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ...
著者Lansky, S, Salama, R, Shoham, Y, Shoham, G.
登録日2019-05-01
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
5TGZ
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BU of 5tgz by Molmil
Crystal Structure of the Human Cannabinoid Receptor CB1
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ...
著者Hua, T, Vemuri, K, Pu, M, Qu, L, Han, G.W, Wu, Y, Zhao, S, Shui, W, Li, S, Korde, A, Laprairie, R.B, Stahl, E.L, Ho, J.H, Zvonok, N, Zhou, H, Kufareva, I, Wu, B, Zhao, Q, Hanson, M.A, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J.
登録日2016-09-28
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Human Cannabinoid Receptor CB1.
Cell, 167, 2016
2AWI
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BU of 2awi by Molmil
Structure of PrgX Y153C mutant
分子名称: PrgX
著者Shi, K, Brown, C.K, Gu, Z.Y, Kozlowicz, B.k, Dunny, G.M, Ohlendorf, D.H, Earhart, C.A.
登録日2005-09-01
公開日2005-12-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of peptide sex pheromone receptor PrgX and PrgX/pheromone complexes and regulation of conjugation in Enterococcus faecalis.
Proc.Natl.Acad.Sci.Usa, 102, 2005

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