6AUI
| Human ribonucleotide reductase large subunit (alpha) with dATP and CDP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Brignole, E.J, Drennan, C.L, Asturias, F.J, Tsai, K.L, Penczek, P.A. | 登録日 | 2017-09-01 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | 3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife, 7, 2018
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3VON
| Crystalstructure of the ubiquitin protease | 分子名称: | Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | 著者 | Sato, Y, Fukai, S. | 登録日 | 2012-01-30 | 公開日 | 2012-05-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. J.Biol.Chem., 287, 2012
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6AYH
| Salmonella enterica GusR | 分子名称: | 4-nitrophenyl beta-D-glucopyranosiduronic acid, GLYCEROL, TetR family transcriptional regulator | 著者 | Little, M.S, Pellock, S.J. | 登録日 | 2017-09-08 | 公開日 | 2017-12-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2BQ1
| Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, FE (III) ION, MAGNESIUM ION, ... | 著者 | Uppsten, M, Farnegardh, M, Domkin, V, Uhlin, U. | 登録日 | 2005-04-26 | 公開日 | 2006-05-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.99 Å) | 主引用文献 | The First Holocomplex Structure of Ribonucleotide Reductase Gives New Insight Into its Mechanism of Action J.Mol.Biol., 359, 2006
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6BA4
| Crystal structure of MYST acetyltransferase domain in complex with Acetyl-CoA cofactor | 分子名称: | ACETYL COENZYME *A, Histone acetyltransferase KAT8, S-{(3S,5R,9R)-1-[(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} ethanethioate, ... | 著者 | Hermans, S.J, Chung, M.C, Peat, T.S, Baell, J.B, Thomas, T, Parker, M.W. | 登録日 | 2017-10-12 | 公開日 | 2018-08-01 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature, 560, 2018
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6Y58
| Binary complex of 14-3-3 sigma (C38N) with the Estrogen Related Receptor gamma (LBD) phosphopeptide | 分子名称: | 14-3-3 protein sigma, Estrogen Related Receptor gamma phosphopeptide, MAGNESIUM ION | 著者 | Somsen, B.A, Sijbesma, E, Leijten-van de Gevel, I.A, Ottmann, C. | 登録日 | 2020-02-25 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
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6Y18
| Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 3 | 分子名称: | 14-3-3 protein sigma, 4-fluoranyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide, CHLORIDE ION, ... | 著者 | Somsen, B.A, Ottmann, C. | 登録日 | 2020-02-11 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
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2M53
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6SKY
| FAT and kinase domain of CtTel1 | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | 登録日 | 2019-08-16 | 公開日 | 2019-10-30 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure, 28, 2020
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6SL0
| Complete CtTel1 dimer with C2 symmetry | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | 登録日 | 2019-08-16 | 公開日 | 2019-10-30 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure, 28, 2020
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3FPN
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1UB4
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6SWG
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5DCX
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7T8L
| BrxR from Acinetobacter BREX type I phage restriction system | 分子名称: | 1,2-ETHANEDIOL, BrxR, CHLORIDE ION | 著者 | Doyle, L, Kaiser, B, Stoddard, B. | 登録日 | 2021-12-16 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Res., 50, 2022
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2N00
| NMR Solution structure of AIM2 PYD from Mus musculus | 分子名称: | Interferon-inducible protein AIM2 | 著者 | Hou, X, Niu, X. | 登録日 | 2015-03-01 | 公開日 | 2015-05-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues Biochem.Biophys.Res.Commun., 461, 2015
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6TB5
| The crystal structure of the DPS2 from DEINOCOCCUS RADIODURANS to 1.83A resolution (sequentially soaked in CaCl2 [5mM] for 20 min, then in Ammonium iron(II) sulfate [10mM] for 2h). | 分子名称: | CALCIUM ION, DNA protection during starvation protein 2, FE (III) ION | 著者 | Cuypers, M.G, McSweeney, S, Romao, C.V, Mitchell, E.P. | 登録日 | 2019-10-31 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | The crystal structure of the DPS2 from DEINOCOCCUS RADIODURANS to 1.83A resolution (sequentially soaked in CaCl2 [5mM] for 20 min, then in Ammonium iron(II) sulfate [10mM] for 2h). To Be Published
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6XXC
| Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 4 | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Estrogen Related Receptor gamma phosphopeptide, ... | 著者 | Somsen, B.A, Ottmann, C. | 登録日 | 2020-01-27 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
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6IF4
| Crystal structure of Tbtudor | 分子名称: | Histone acetyltransferase | 著者 | Gao, J, Ye, K, Diwu, Y, Liao, S, Tu, X. | 登録日 | 2018-09-18 | 公開日 | 2019-09-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.934 Å) | 主引用文献 | Crystal structure of TbEsa1 presumed Tudor domain from Trypanosoma brucei. J.Struct.Biol., 209, 2020
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6Z8X
| X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3Leu), which contains leucyl amide in the side chain of Thy3 at N3. | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, Prothrombin, ... | 著者 | Troisi, R, Timofeev, E.N, Sica, F. | 登録日 | 2020-06-02 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12. Mol Ther Nucleic Acids, 23, 2021
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1RNH
| STRUCTURE OF RIBONUCLEASE H PHASED AT 2 ANGSTROMS RESOLUTION BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN | 分子名称: | RIBONUCLEASE HI, SULFATE ION | 著者 | Yang, W, Hendrickson, W.A, Crouch, R.J, Satow, Y. | 登録日 | 1990-07-11 | 公開日 | 1991-10-15 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein. Science, 249, 1990
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6SL1
| Structure of the open conformation of CtTel1 | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | 登録日 | 2019-08-16 | 公開日 | 2019-10-30 | 最終更新日 | 2020-05-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure, 28, 2020
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2XSZ
| The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2 | 著者 | Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A. | 登録日 | 2010-10-01 | 公開日 | 2011-10-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex. J.Struct.Biol., 176, 2011
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6SKZ
| Structure of the closed conformation of CtTel1 | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1 | 著者 | Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P. | 登録日 | 2019-08-16 | 公開日 | 2019-10-30 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. Structure, 28, 2020
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2IOC
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