6AUI
Human ribonucleotide reductase large subunit (alpha) with dATP and CDP
Summary for 6AUI
Entry DOI | 10.2210/pdb6aui/pdb |
EMDB information | 7006 |
Descriptor | Ribonucleoside-diphosphate reductase large subunit, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | ribonucleotide reductase electron transfer radical chemistry thiyl radical, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 562707.25 |
Authors | Brignole, E.J.,Drennan, C.L.,Asturias, F.J.,Tsai, K.L.,Penczek, P.A. (deposition date: 2017-09-01, release date: 2018-04-18, Last modification date: 2024-03-13) |
Primary citation | Brignole, E.J.,Tsai, K.L.,Chittuluru, J.,Li, H.,Aye, Y.,Penczek, P.A.,Stubbe, J.,Drennan, C.L.,Asturias, F. 3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife, 7:-, 2018 Cited by PubMed: 29460780DOI: 10.7554/eLife.31502 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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