6AUI

Human ribonucleotide reductase large subunit (alpha) with dATP and CDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Ribonucleoside-diphosphate reductase large subunit	polymer	812	92350.4	6	UniProt (P23921) Pfam (PF03477) Pfam (PF00317) Pfam (PF02867) In PDB	Homo sapiens (Human)	Ribonucleoside-diphosphate reductase subunit M1,Ribonucleotide reductase large subunit
2	E, F, A, B, C...	2'-DEOXYADENOSINE 5'-TRIPHOSPHATE	non-polymer		491.2	12	Chemie (DTP)
3	E, F, A, B, C...	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
4	E, F, A, B, C...	CYTIDINE-5'-DIPHOSPHATE	non-polymer		403.2	6	Chemie (CDP)
5		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 792 (UniProt: P23921)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	554102.3
Non-Polymers*	Number of molecules	30
	Total formula weight	8604.9
All*	Total formula weight	562707.2

*Water molecules are not included.