8QPY
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8QQE
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![BU of 8qqe by Molmil](/molmil-images/mine/8qqe) | Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2 | 分子名称: | Breast cancer type 2 susceptibility protein, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Miron, S, Legrand, P, Zinn-Justin, S. | 登録日 | 2023-10-04 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (3.461 Å) | 主引用文献 | DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces. Nucleic Acids Res., 52, 2024
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8QRN
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![BU of 8qrn by Molmil](/molmil-images/mine/8qrn) | mt-SSU in GTPBP8 knock-out cells, state 4 | 分子名称: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | 著者 | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | 登録日 | 2023-10-09 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | GTPBP8 plays a role in mitoribosome formation in human mitochondria. Nat Commun, 15, 2024
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8RLN
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![BU of 8rln by Molmil](/molmil-images/mine/8rln) | Crystal structure of human adenosine A2A receptor (construct A2A-PSB2-bRIL) complexed with the partial antagonist LUF5834 at the orthosteric pocket | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-azanyl-4-(4-hydroxyphenyl)-6-(1~{H}-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile, ... | 著者 | Strater, N, Claff, T, Weisse, R.H, Muller, C.E. | 登録日 | 2024-01-03 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A 2A Receptor. Acs Pharmacol Transl Sci, 7, 2024
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8RPI
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![BU of 8rpi by Molmil](/molmil-images/mine/8rpi) | JanthE from Janthinobacterium sp. HH01, lactyl-ThDP | 分子名称: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Lanza, L, Leogrande, C, Rabe von Pappenheim, F, Tittmann, K, Mueller, M. | 登録日 | 2024-01-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Identification and Characterization of Thiamine Diphosphate-Dependent Lyases with an Unusual CDG Motif. Angew.Chem.Int.Ed.Engl., 63, 2024
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8RKT
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![BU of 8rkt by Molmil](/molmil-images/mine/8rkt) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K Cas12k domain local-refinement map | 分子名称: | MAGNESIUM ION, Non-target strand - LE, ShCas12k, ... | 著者 | Tenjo-Castano, F, Mesa, P, Montoya, G. | 登録日 | 2023-12-30 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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8QZH
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![BU of 8qzh by Molmil](/molmil-images/mine/8qzh) | Crystal structure of apo-PptT from Mycobacterium tuberculosis | 分子名称: | 4'-phosphopantetheinyl transferase PptT, ACETATE ION, MAGNESIUM ION | 著者 | Gavalda, S, Carivenc, C, Mourey, L, Pedelacq, J.D. | 登録日 | 2023-10-27 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases Acs Catalysis, 14, 2024
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8RPB
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![BU of 8rpb by Molmil](/molmil-images/mine/8rpb) | Structure of S79 Fab in complex with IgV domain of human PD-L1 | 分子名称: | CHLORIDE ION, GLYCEROL, Programmed cell death 1 ligand 1, ... | 著者 | Svensson, A, Kelpsas, V, Laursen, M, Rose, N. | 登録日 | 2024-01-15 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1. Mabs, 16, 2024
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8QUS
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7ZKN
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![BU of 7zkn by Molmil](/molmil-images/mine/7zkn) | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form gamma | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[13-methyl-5,7,12,14-tetrakis(oxidanylidene)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]propyl 3-[5,7,12,14-tetrakis(oxidanylidene)-13-(3-oxidanylpropyl)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1,3,8(16),9,11(15)-pentaen-6-yl]propyl hydrogen phosphate, 3-[5-[3-bis(oxidanyl)phosphanyloxypropoxy]naphthalen-1-yl]oxypropyl 3-(5-oxidanylnaphthalen-1-yl)oxypropyl hydrogen phosphate, ... | 著者 | Troisi, R, Sica, F. | 登録日 | 2022-04-13 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers. Mol Ther Nucleic Acids, 30, 2022
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8RKU
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![BU of 8rku by Molmil](/molmil-images/mine/8rku) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsC domain local-refinement map | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target strand - LE, ... | 著者 | Tenjo-Castano, F, Mesa, P, Montoya, G. | 登録日 | 2023-12-30 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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7ZKM
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![BU of 7zkm by Molmil](/molmil-images/mine/7zkm) | X-ray structure of the complex between human alpha thrombin and a pseudo-cyclic thrombin binding aptamer (TBA-NNp/DDp) - Crystal form beta | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[13-methyl-5,7,12,14-tetrakis(oxidanylidene)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(15),2,4(16),8,10-pentaen-6-yl]propyl 3-[5,7,12,14-tetrakis(oxidanylidene)-13-(3-oxidanylpropyl)-6,13-diazatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1,3,8(16),9,11(15)-pentaen-6-yl]propyl hydrogen phosphate, 3-[5-[3-bis(oxidanyl)phosphanyloxypropoxy]naphthalen-1-yl]oxypropyl 3-(5-oxidanylnaphthalen-1-yl)oxypropyl hydrogen phosphate, ... | 著者 | Troisi, R, Sica, F. | 登録日 | 2022-04-13 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers. Mol Ther Nucleic Acids, 30, 2022
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8RPH
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![BU of 8rph by Molmil](/molmil-images/mine/8rph) | JanthE from Janthinobacterium sp. HH01,ketobutyryl-ThDP | 分子名称: | (2~{S})-2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-2-yl]-2-oxidanyl-butanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Lanza, L, Leogrande, C, Rabe von Pappenheim, F, Tittmann, K, Mueller, M. | 登録日 | 2024-01-16 | 公開日 | 2024-06-12 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Identification and Characterization of Thiamine Diphosphate-Dependent Lyases with an Unusual CDG Motif. Angew.Chem.Int.Ed.Engl., 63, 2024
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8QNF
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![BU of 8qnf by Molmil](/molmil-images/mine/8qnf) | Crystal structure of the Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase | 分子名称: | Condensation domain TomBC from the Tomaymycin non-ribosomal peptide synthetase, FORMIC ACID, GLYCEROL, ... | 著者 | Karanth, M, Schmelz, S, Kirkpatrick, J, Krausze, J, Scrima, A, Carlomagno, T. | 登録日 | 2023-09-26 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The specificity of intermodular recognition in a prototypical nonribosomal peptide synthetase depends on an adaptor domain. Sci Adv, 10, 2024
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8QRX
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8R3Z
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6ZBW
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![BU of 6zbw by Molmil](/molmil-images/mine/6zbw) | Structure of the D125N mutant of the catalytic domain of the Bacillus circulans alpha-1,6 Mannanase in complex with an alpha-1,6-alpha-manno-cyclophellitol trisaccharide inhibitor | 分子名称: | (1~{S},4~{S},5~{R})-6-(hydroxymethyl)cyclohexane-1,2,3,4,5-pentol, 1,2-ETHANEDIOL, Alpha-1,6-mannanase, ... | 著者 | Davies, G.J, Offen, W.A. | 登録日 | 2020-06-09 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Development of Non-Hydrolysable Oligosaccharide Activity-Based Inactivators for Endoglycanases: A Case Study on alpha-1,6 Mannanases. Chemistry, 27, 2021
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8QSX
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8RKV
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![BU of 8rkv by Molmil](/molmil-images/mine/8rkv) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsB domain local-refinement map | 分子名称: | LE, MAGNESIUM ION, Non-target strand - LE, ... | 著者 | Tenjo-Castano, F, Mesa, P, Montoya, G. | 登録日 | 2023-12-30 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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8QWT
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8R47
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![BU of 8r47 by Molmil](/molmil-images/mine/8r47) | AL amyloid fibril from the FOR010 light chain | 分子名称: | lambda 3 immunoglobulin light chain fragment, residues 4-116 | 著者 | Pfeiffer, P.B, Banerjee, S, Schmidt, M, Faendrich, M. | 登録日 | 2023-11-13 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.25 Å) | 主引用文献 | Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. Nat Commun, 15, 2024
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8QOI
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![BU of 8qoi by Molmil](/molmil-images/mine/8qoi) | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | 分子名称: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | 著者 | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | 登録日 | 2023-09-29 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | 主引用文献 | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 2024
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4YDL
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![BU of 4ydl by Molmil](/molmil-images/mine/4ydl) | Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ... | 著者 | Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2015-02-22 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell, 161, 2015
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6MPM
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![BU of 6mpm by Molmil](/molmil-images/mine/6mpm) | Racemic M2-TM I42A crystallized from racemic detergent | 分子名称: | Matrix protein 2, octyl beta-D-glucopyranoside | 著者 | Kreitler, D.F, Yao, Z, Mortenson, D.E, Forest, K.T, Gellman, S.H. | 登録日 | 2018-10-07 | 公開日 | 2019-01-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation. J. Am. Chem. Soc., 141, 2019
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1BQ1
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![BU of 1bq1 by Molmil](/molmil-images/mine/1bq1) | E. COLI THYMIDYLATE SYNTHASE MUTANT N177A IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP) | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | 著者 | Reyes, C.L, Sage, C.R, Rutenber, E.E, Finer-Moore, J.S, Stroud, R.M. | 登録日 | 1998-08-20 | 公開日 | 1999-05-18 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer. J.Mol.Biol., 284, 1998
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