3N2K
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![BU of 3n2k by Molmil](/molmil-images/mine/3n2k) | TUBULIN-NSC 613862: RB3 Stathmin-like domain complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | 登録日 | 2010-05-18 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
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8CUR
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![BU of 8cur by Molmil](/molmil-images/mine/8cur) | Crystal structure of Cdk2 in complex with Cyclin A inhibitor 6-[(E)-2-(4-chlorophenyl)ethenyl]-2-{[(2R)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid | 分子名称: | 6-[(E)-2-(4-chlorophenyl)ethenyl]-2-{[(2R)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}quinoline-4-carboxylic acid, Cyclin-dependent kinase 2 | 著者 | Tripathi, S.M, Tambo, C.S, Kiss, G, Rubin, S.M. | 登録日 | 2022-05-17 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. Acs Chem.Biol., 18, 2023
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5W6L
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![BU of 5w6l by Molmil](/molmil-images/mine/5w6l) | Crystal Structure of RRSP, a MARTX Toxin Effector Domain from Vibrio vulnificus CMCP6 | 分子名称: | CHLORIDE ION, GLYCEROL, RTX repeat-containing cytotoxin, ... | 著者 | Minasov, G, Wawrzak, Z, Biancucci, M, Shuvalova, L, Dubrovska, I, Satchell, K.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-06-16 | 公開日 | 2018-06-27 | 最終更新日 | 2018-10-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling. Sci Signal, 11, 2018
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3N2G
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![BU of 3n2g by Molmil](/molmil-images/mine/3n2g) | TUBULIN-NSC 613863: RB3 Stathmin-like domain complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | 登録日 | 2010-05-18 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
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2B9Z
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![BU of 2b9z by Molmil](/molmil-images/mine/2b9z) | Solution structure of FHV B2, a viral suppressor of RNAi | 分子名称: | B2 protein | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | 登録日 | 2005-10-13 | 公開日 | 2005-11-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. Embo Rep., 6, 2005
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4BTE
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![BU of 4bte by Molmil](/molmil-images/mine/4bte) | DJ-1 Cu(I) complex | 分子名称: | COPPER (I) ION, PROTEIN DJ-1 | 著者 | Puno, M.R.A, Odell, M, Moody, P.C.E. | 登録日 | 2013-06-14 | 公開日 | 2013-11-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Structure of Cu(I)-Bound Dj-1 Reveals a Biscysteinate Metal Binding Site at the Homodimer Interface: Insights Into Mutational Inactivation of Dj-1 in Parkinsonism. J.Am.Chem.Soc., 135, 2013
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1DSX
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![BU of 1dsx by Molmil](/molmil-images/mine/1dsx) | KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT | 分子名称: | PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL) | 著者 | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | 登録日 | 2000-01-10 | 公開日 | 2000-09-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell(Cambridge,Mass.), 102, 2000
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4J4L
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4OM7
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![BU of 4om7 by Molmil](/molmil-images/mine/4om7) | Crystal structure of TIR domain of TLR6 | 分子名称: | Toll-like receptor 6 | 著者 | Park, H.H, Jang, T.H. | 登録日 | 2014-01-26 | 公開日 | 2014-08-06 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | 主引用文献 | Crystal Structure of TIR Domain of TLR6 Reveals Novel Dimeric Interface of TIR-TIR Interaction for Toll-Like Receptor Signaling Pathway. J.Mol.Biol., 426, 2014
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1LE6
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![BU of 1le6 by Molmil](/molmil-images/mine/1le6) | CARBOXYLIC ESTER HYDROLASE, P 1 21 1 SPACE GROUP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Group X Secretory Phospholipase A2 | 著者 | Pan, Y.H, Jain, M.K, Bahnson, B.J. | 登録日 | 2002-04-09 | 公開日 | 2002-08-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes. J.Biol.Chem., 277, 2002
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4C7M
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![BU of 4c7m by Molmil](/molmil-images/mine/4c7m) | The crystal structure of TcpB or BtpA TIR domain | 分子名称: | Toll/interleukin-1 receptor domain-containing protein | 著者 | Alaidarous, M, Ve, T, Casey, L.W, Valkov, E, Ullah, M.O, Schembri, M.A, Mansell, A, Sweet, M.J, Kobe, B. | 登録日 | 2013-09-23 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB. J.Biol.Chem., 289, 2014
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2HNU
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![BU of 2hnu by Molmil](/molmil-images/mine/2hnu) | Crystal Structure of a Dipeptide Complex of Bovine Neurophysin-I | 分子名称: | Oxytocin-neurophysin 1, PHENYLALANINE, TYROSINE | 著者 | Li, X, Lee, H, Wu, J, Breslow, E. | 登録日 | 2006-07-13 | 公開日 | 2007-04-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: crystal structures and mutation studies of bovine neurophysin-I. Protein Sci., 16, 2007
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1LE7
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![BU of 1le7 by Molmil](/molmil-images/mine/1le7) | CARBOXYLIC ESTER HYDROLASE, C 2 2 21 space group | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Group X Secretory Phospholipase A2 | 著者 | Pan, Y.H, Jain, M.K, Bahnson, B.J. | 登録日 | 2002-04-09 | 公開日 | 2002-08-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes. J.Biol.Chem., 277, 2002
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4IRB
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![BU of 4irb by Molmil](/molmil-images/mine/4irb) | Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4 | 分子名称: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | 著者 | Schormann, N, Zhukovskaya, N, Sartmatova, D, Nuth, M, Ricciardi, R.P, Chattopadhyay, D. | 登録日 | 2013-01-14 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mutations at the dimer interface affect both function and structure of the Vaccinia virus uracil DNA glycosylase To be Published
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3C7X
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![BU of 3c7x by Molmil](/molmil-images/mine/3c7x) | Hemopexin-like domain of matrix metalloproteinase 14 | 分子名称: | CHLORIDE ION, Matrix metalloproteinase-14, SODIUM ION | 著者 | Tochowicz, A, Itoh, Y, Maskos, K, Bode, W, Goettig, P. | 登録日 | 2008-02-08 | 公開日 | 2009-02-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions J.Biol.Chem., 286, 2011
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4EKJ
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![BU of 4ekj by Molmil](/molmil-images/mine/4ekj) | Crystal structure of a monomeric beta-xylosidase from Caulobacter crescentus CB15 | 分子名称: | Beta-xylosidase, SULFATE ION | 著者 | Santos, C.R, Polo, C.C, Correa, J.M, Simao, R.C.G, Seixas, F.A.V, Murakami, M.T. | 登録日 | 2012-04-09 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The accessory domain changes the accessibility and molecular topography of the catalytic interface in monomeric GH39 beta-xylosidases. Acta Crystallogr.,Sect.D, 68, 2012
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2HNW
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![BU of 2hnw by Molmil](/molmil-images/mine/2hnw) | Crystal Structure of the F91STOP mutant of des1-6 Bovine Neurophysin-I, unliganded state | 分子名称: | Oxytocin-neurophysin 1 | 著者 | Li, X, Lee, H, Wu, J, Breslow, E. | 登録日 | 2006-07-13 | 公開日 | 2007-04-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: crystal structures and mutation studies of bovine neurophysin-I. Protein Sci., 16, 2007
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4V2L
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4V2M
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4V2N
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5L0O
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5HBI
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![BU of 5hbi by Molmil](/molmil-images/mine/5hbi) | SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72I, CO-LIGANDED FORM | 分子名称: | CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Royer Junior, W.E. | 登録日 | 1998-06-24 | 公開日 | 1998-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity. J.Mol.Biol., 284, 1998
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4LCO
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![BU of 4lco by Molmil](/molmil-images/mine/4lco) | Crystal structure of NE0047 with complex with substrate ammeline | 分子名称: | 4,6-diamino-1,3,5-triazin-2-ol, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION | 著者 | Bitra, A, Biswas, A, Anand, R. | 登録日 | 2013-06-22 | 公開日 | 2014-01-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
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4LCP
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![BU of 4lcp by Molmil](/molmil-images/mine/4lcp) | Crytsal structure of NE0047 in complex with 2,6-diaminopurine | 分子名称: | 9H-PURINE-2,6-DIAMINE, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION | 著者 | Bitra, A, Biswas, A, Anand, R. | 登録日 | 2013-06-22 | 公開日 | 2014-01-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase Biochemistry, 52, 2013
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1XGP
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![BU of 1xgp by Molmil](/molmil-images/mine/1xgp) | |