4Y1U
 
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8R3L
 | | Influenza A/H7N9 polymerase in pre-initiation state, intermediate conformation (I) with PB2-C(I), ENDO(T), and Pol II pS5 CTD peptide mimic bound in site 1A/2A | | 分子名称: | 3' vRNA end (51-mer vRNA loop), Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Arragain, B, Cusack, S. | | 登録日 | 2023-11-09 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome.
Nat Commun, 15, 2024
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4Y26
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8RI3
 | | Crystal structure of transplatin/B-DNA adduct obtained upon 7 days of soaking | | 分子名称: | AMMONIA, CHLORIDE ION, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), ... | | 著者 | Tito, G, Troisi, R, Ferraro, G, Sica, F, Merlino, A. | | 登録日 | 2023-12-18 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer.
Dalton Trans, 53, 2024
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1NQL
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8R5H
 | | Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2 | | 分子名称: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 5-azanylpentan-2-one, Bromodomain-containing protein 4, ... | | 著者 | Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A. | | 登録日 | 2023-11-16 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
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8R6H
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8RC7
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8QZK
 | | Catalytic core of endo-alpha-N-acetylgalactosaminidase from Bifidobacterium longum (EngBF) concieved by deep network hallucination: dEngBF4 Hexagonal form | | 分子名称: | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE | | 著者 | Aghajari, N, Hansen, A.L, Thiesen, F.F, Crehuet, R, Marcos, E, Willemoes, M. | | 登録日 | 2023-10-27 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination.
Acs Synth Biol, 13, 2024
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8RAS
 | | Plastid-encoded RNA polymerase transcription elongation complex | | 分子名称: | DNA (81-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Webster, M.W, Pramanick, I, Vergara-Cruces, A. | | 登録日 | 2023-12-01 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | | 主引用文献 | Structure of the plant plastid-encoded RNA polymerase.
Cell, 187, 2024
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8QGT
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6ZJT
 | | Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant E441Q in complex with lactulose | | 分子名称: | ACETATE ION, Beta-galactosidase, SODIUM ION, ... | | 著者 | Rutkiewicz, M, Bujacz, A, Bujacz, G. | | 登録日 | 2020-06-29 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB.
Int J Mol Sci, 21, 2020
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8R4U
 | | Structure of salt-inducible kinase 3 with inhibitors | | 分子名称: | 8-[(5-azanyl-1,3-dioxan-2-yl)methyl]-6-[2-chloranyl-4-(3-fluoranylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one, SULFATE ION, Serine/threonine-protein kinase SIK3, ... | | 著者 | Kack, H, Oster, L. | | 登録日 | 2023-11-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.416 Å) | | 主引用文献 | The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
J.Biol.Chem., 300, 2024
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4XOT
 | | Tailspike protein mutant E372Q of E. coli bacteriophage HK620 in complex with pentasaccharide | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... | | 著者 | Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. | | 登録日 | 2015-01-16 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
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1B0G
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7PBZ
 | | a1b3 GABA-A receptor + GABA + Zn2+ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | 著者 | Miller, P.S, Kasaragod, V.B. | | 登録日 | 2021-08-03 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | | 主引用文献 | Mechanisms of inhibition and activation of extrasynaptic alpha beta GABA A receptors.
Nature, 602, 2022
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8R8P
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8R60
 | | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2023-11-19 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
To Be Published
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8R6D
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8RQF
 | | Cryo-EM structure of human NTCP-Bulevirtide complex | | 分子名称: | Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ... | | 著者 | Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P. | | 登録日 | 2024-01-18 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Cryo-EM structure of human NTCP-Bulevirtide complex
To Be Published
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8RHN
 | | Structure of the 55LCC ATPase complex | | 分子名称: | ATPase family gene 2 protein homolog A, ATPase family gene 2 protein homolog B, Cyclin-dependent kinase 2-interacting protein, ... | | 著者 | Foglizzo, M, Degtjarik, O, Zeqiraj, E. | | 登録日 | 2023-12-15 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity.
Cell, 187, 2024
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4XQU
 | | Crystal structure of hemagglutinin from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 3'-SLN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | 著者 | Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A. | | 登録日 | 2015-01-20 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
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8QIC
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8R5Z
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8PV2
 | | Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 | | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | | 登録日 | 2023-07-17 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation.
Embo Rep., 24, 2023
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