PDB: 2561 件ウェブページステータス検索Chemie searchBIRD

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3ADB	Crystal structure of O-phosphoseryl-tRNA kinase complexed with selenocysteine tRNA and AMPPNP (crystal type 1) 分子名称: L-seryl-tRNA(Sec) kinase, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Itoh, Y, Chiba, S, Sekine, S, Yokoyama, S. 登録日 2010-01-18 公開日 2010-07-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine Mol.Cell, 39, 2010
2QK4	Human glycinamide ribonucleotide synthetase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Lehtio, L, Welin, M, Arrowsmith, C.H, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Herman, M.D, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) 登録日 2007-07-10 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural studies of tri-functional human GART. Nucleic Acids Res., 38, 2010
3TEJ	Crystal structure of a domain fragment involved in peptide natural product biosynthesis 分子名称: Enterobactin synthase component F 著者 Liu, Y, Zheng, T, Bruner, S.D. 登録日 2011-08-15 公開日 2012-01-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for phosphopantetheinyl carrier domain interactions in the terminal module of nonribosomal peptide synthetases. Chem.Biol., 18, 2011
4AUQ	Structure of BIRC7-UbcH5b-Ub complex. 分子名称: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 7, POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 D2, ... 著者 Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T. 登録日 2012-05-21 公開日 2012-08-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.176 Å) 主引用文献 Birc7-E2 Ubiquitin Conjugate Structure Reveals the Mechanism of Ubiquitin Transfer by a Ring Dimer. Nat.Struct.Mol.Biol., 19, 2012
3C9T	AaThiL complexed with AMPPCP and TMP 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, THIAMIN PHOSPHATE, ... 著者 McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. 登録日 2008-02-18 公開日 2008-03-18 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry, 47, 2008
7LB6	PDX1.2/PDX1.3 co-expression complex 分子名称: Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2 著者 Novikova, I.V, Evans, J.E. 登録日 2021-01-07 公開日 2021-09-22 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Tunable Heteroassembly of a Plant Pseudoenzyme-Enzyme Complex. Acs Chem.Biol., 16, 2021
3C9U	AaThiL complexed with ADP and TPP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... 著者 McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. 登録日 2008-02-18 公開日 2008-03-18 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry, 47, 2008
3B7W	Crystal structure of human acyl-CoA synthetase medium-chain family member 2A, with L64P mutation 分子名称: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, CHLORIDE ION, ... 著者 Pilka, E.S, Kochan, G.T, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2007-10-31 公開日 2007-11-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A. J.Mol.Biol., 388, 2009
3TW7	Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A 分子名称: CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-12 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3C9S	AaThiL complexed with AMPPCP 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Thiamine monophosphate kinase 著者 McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. 登録日 2008-02-18 公開日 2008-03-18 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry, 47, 2008
2WD9	CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN 分子名称: ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, IBUPROFEN, ... 著者 Yue, W.W, Kochan, G.T, Pilka, E.S, Bhatia, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U. 登録日 2009-03-21 公開日 2009-04-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A. J.Mol.Biol., 388, 2009
3TW6	Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 St Maurice, M, Kumar, S, Lietzan, A.D. 登録日 2011-09-21 公開日 2011-10-19 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
7LV3	Crystal structure of human protein kinase G (PKG) R-C complex in inhibited state 分子名称: 1,2-ETHANEDIOL, Isoform Beta of cGMP-dependent protein kinase 1, MANGANESE (II) ION, ... 著者 Sharma, R, Lying, Q, Casteel, D, Kim, C. 登録日 2021-02-23 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 An auto-inhibited state of protein kinase G and implications for selective activation. Elife, 11, 2022
6S1I	Crystal Structure of DYRK1A with small molecule inhibitor 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Sorrell, F.J, Henderson, S.H, Redondo, C, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Elkins, J.M. 登録日 2019-06-18 公開日 2019-06-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. Acs Med.Chem.Lett., 11, 2020
1TWJ	Crystal Structure of B. subtilis PurS P21 Crystal Form 分子名称: Hypothetical UPF0062 protein yexA 著者 Anand, R, Ealick, S.E, Hoskins, A.A, Stubbe, J. 登録日 2004-07-01 公開日 2004-08-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Model for the Bacillus subtilis Formylglycinamide Ribonucleotide Amidotransferase Multiprotein Complex Biochemistry, 43, 2004
3GPC	Crystal structure of human Acyl-CoA synthetase medium-chain family member 2A (L64P mutation) in a complex with CoA 分子名称: Acyl-coenzyme A synthetase ACSM2A, COENZYME A, MAGNESIUM ION 著者 Pilka, E.S, Kochan, G.T, Yue, W.W, Bhatia, C, Von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2009-03-23 公開日 2009-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A J.Mol.Biol., 388, 2009
6FQB	MurT/GatD peptidoglycan amidotransferase complex from Streptococcus pneumoniae R6 分子名称: Cobyric acid synthase, GLUTAMINE, Mur ligase family protein 著者 Morlot, C, Contreras-Martel, C, Leisico, F, Straume, D, Peters, K, Hegnar, O.A, Simon, N, Villard, A.M, Breukink, E, Gravier-Pelletier, C, Le Corre, L, Vollmer, W, Pietrancosta, N, Havarstein, L.S, Zapun, A. 登録日 2018-02-13 公開日 2018-08-22 最終更新日 2018-11-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae. Nat Commun, 9, 2018
6NUD	Small conformation of ssRNA-bound CRISPR_Csm complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... 著者 Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. 登録日 2019-01-31 公開日 2019-03-13 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
6NUE	Small conformation of apo CRISPR_Csm complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CRISPR system Cms protein Csm2, CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), ... 著者 Zhang, K, Pintilie, G, Li, S, Zhu, Y, Chiu, W, Huang, Z. 登録日 2019-01-31 公開日 2019-03-13 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry. Cell Res., 29, 2019
6JT9	Crystal Structure of D464A mutant of FGAM Synthetase 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. 登録日 2019-04-10 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
6JT8	Crystal structure of 450-451_deletion mutant of FGAM Synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. 登録日 2019-04-10 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
3LN1	Structure of celecoxib bound at the COX-2 active site 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, ... 著者 Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L. 登録日 2010-02-01 公開日 2010-10-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life. Bioorg.Med.Chem.Lett., 20, 2010
5MNI	Escherichia coli AGPase mutant R130A apo form 分子名称: Glucose-1-phosphate adenylyltransferase 著者 Cifuente, J.O, Comino, N, Marina, A, Orrantia, A, Eguskiza, A, Guerin, M.E. 登録日 2016-12-13 公開日 2017-03-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases. J. Biol. Chem., 292, 2017
6LYM	Crystal structure of D657A mutant of formylglycinamidine synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Sharma, N, Tanwar, A.S, Anand, R. 登録日 2020-02-14 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
6LYO	Crystal Structure of H296A mutant of Formylglycinamidine Synthetase 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Sharma, N, Tanwar, A.S, Anand, R. 登録日 2020-02-15 公開日 2021-02-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022

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