8Q5I
| Structure of Candida albicans 80S ribosome in complex with cephaeline | 分子名称: | 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. | 登録日 | 2023-08-09 | 公開日 | 2023-09-13 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
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8IOI
| Crystal Structure of PadR- family transcriptional regulator Rv1176c from Mycobacterium tuberculosis H37Rv. | 分子名称: | CHLORIDE ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | 著者 | Yadav, V, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A. | 登録日 | 2023-03-11 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Structural and biophysical characterization of PadR family protein Rv1176c of Mycobacterium tuberculosis H37Rv. Int.J.Biol.Macromol., 263, 2024
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1S2R
| A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2 | 分子名称: | 5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3', SPERMINE | 著者 | Woods, K.K, Maehigashi, T, Howerton, S.B, Tannenbaum, S, Williams, L.D. | 登録日 | 2004-01-09 | 公開日 | 2005-01-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2. J.Am.Chem.Soc., 126, 2004
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2N26
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4QKQ
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5EW5
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1KCF
| Crystal Structure of the Yeast Mitochondrial Holliday Junction Resolvase, Ydc2 | 分子名称: | HYPOTHETICAL 30.2 KD PROTEIN C25G10.02 IN CHROMOSOME I, SULFATE ION | 著者 | Ceschini, S, Keeley, A, McAlister, M.S.B, Oram, M, Phelan, J, Pearl, L.H, Tsaneva, I.R, Barrett, T.E. | 登録日 | 2001-11-08 | 公開日 | 2001-11-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the fission yeast mitochondrial Holliday junction resolvase Ydc2. EMBO J., 20, 2001
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2N25
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2YDJ
| Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas | 分子名称: | 5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide, PHOSPHATE ION, SERINE/THREONINE-PROTEIN KINASE CHK1 | 著者 | Read, J.A, Breed, J, Haye, H, McCall, E, Rowsell, S, Vallentine, A, White, A. | 登録日 | 2011-03-22 | 公開日 | 2012-01-25 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(Piperidin-3-Yl)-3-Ureidothiophene-2-Carboxamide (Azd7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas. J.Med.Chem., 55, 2012
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3ZTH
| Crystal structure of Stu0660 of Streptococcus thermophilus | 分子名称: | MAGNESIUM ION, STU0660 | 著者 | Lee, K.-H, Robinson, H, Oh, B.-H. | 登録日 | 2011-07-08 | 公開日 | 2012-07-11 | 最終更新日 | 2012-10-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification, Structural, and Biochemical Characterization of a Group of Large Csn2 Proteins Involved in Crispr-Mediated Bacterial Immunity. Proteins, 80, 2012
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7WJU
| Cryo-EM structure of the AsCas12f1-sgRNAv1-dsDNA ternary complex | 分子名称: | Non-target strand, OrfB_Zn_ribbon domain-containing protein, Target strand, ... | 著者 | Wu, Z, Liu, D, Shen, H, Ji, Q. | 登録日 | 2022-01-07 | 公開日 | 2023-01-18 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Structure-directed functional evolution of the miniature CRISPR-AsCas12f1 system To Be Published
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3M03
| Crystal structure of human Orc6 fragment | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Origin recognition complex subunit 6, SULFATE ION | 著者 | Liu, S.X, Wu, L.J, Sun, J, Wang, H.F, Liu, Y.F. | 登録日 | 2010-03-02 | 公開日 | 2011-03-09 | 最終更新日 | 2014-03-05 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB Proc.Natl.Acad.Sci.USA, 108, 2011
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6JXA
| Tel1 kinase compact monomer | 分子名称: | Serine/threonine-protein kinase TEL1 | 著者 | Xin, J. | 登録日 | 2019-04-23 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of allosteric regulation of Tel1/ATM kinase. Cell Res., 29, 2019
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1N25
| Crystal structure of the SV40 Large T antigen helicase domain | 分子名称: | Large T Antigen, ZINC ION | 著者 | Li, D, Zhao, R, Lilyestrom, W, Gai, D, Zhang, R, DeCaprio, J.A, Fanning, E, Jochimiak, A, Szakonyi, G, Chen, X.S. | 登録日 | 2002-10-21 | 公開日 | 2003-06-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen Nature, 423, 2003
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3I55
| Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... | 著者 | Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. | 登録日 | 2009-07-03 | 公開日 | 2010-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
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5YZ0
| Cryo-EM Structure of human ATR-ATRIP complex | 分子名称: | ATR-interacting protein, Serine/threonine-protein kinase ATR | 著者 | Rao, Q, Liu, M, Tian, Y, Wu, Z, Wang, H, Wang, J, Xu, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-01-31 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM structure of human ATR-ATRIP complex. Cell Res., 28, 2018
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8I4X
| Cryo-EM structure of 5-subunit Smc5/6 | 分子名称: | E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 5, Nse6, ... | 著者 | Qian, L, Jun, Z, Xiang, Z, Zhaoning, W, Tong, C, Duo, J, Zhenguo, C, Wang, L. | 登録日 | 2023-01-21 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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8I21
| Cryo-EM structure of 6-subunit Smc5/6 arm region | 分子名称: | E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6 | 著者 | Jun, Z, Qian, L, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W. | 登録日 | 2023-01-13 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (6.02 Å) | 主引用文献 | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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5XFO
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6WUC
| The yeast Ctf3 complex with Cnn1-Wip1 | 分子名称: | Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ... | 著者 | Hinshaw, S.M, Harrison, S.C. | 登録日 | 2020-05-04 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | The Structural Basis for Kinetochore Stabilization by Cnn1/CENP-T. Curr.Biol., 30, 2020
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6JXC
| Tel1 kinase butterfly symmetric dimer | 分子名称: | Serine/threonine-protein kinase TEL1 | 著者 | Xin, J. | 登録日 | 2019-04-23 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of allosteric regulation of Tel1/ATM kinase. Cell Res., 29, 2019
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6WXW
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1PUP
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5XFN
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3GGR
| Crystal Structure of the Human Rad9-Hus1-Rad1 complex | 分子名称: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1 | 著者 | Xu, M, Bai, L, Hang, H.Y, Jiang, T. | 登録日 | 2009-03-02 | 公開日 | 2009-06-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex J.Biol.Chem., 284, 2009
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