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8JDK
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Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T.
登録日2023-05-14
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth.
Cell, 186, 2023
7VBZ
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Matrix arm of active state CI from Rotenone-NADH dataset
分子名称: (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ...
著者Gu, J.K, Yang, M.J.
登録日2021-09-01
公開日2022-04-06
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
8K2C
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BU of 8k2c by Molmil
Cryo-EM structure of the human 80S ribosome with Tigecycline
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Li, X, Wang, M, Cheng, J.
登録日2023-07-12
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
8P18
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BU of 8p18 by Molmil
E167K RF2 on E. coli 70S release complex with UGG (Structure III)
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S.
登録日2023-05-11
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献The compensatory mechanism of a naturally evolved E167K RF2 counteracting the loss of RF1 in bacteria
To Be Published
8OO0
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Chaetomium thermophilum Methionine Aminopeptidase 2 autoproteolysis product at the 80S ribosome
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S0, ...
著者Klein, M.A, Wild, K, Kisonaite, M, Sinning, I.
登録日2023-04-04
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Nat Commun, 15, 2024
8P5D
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BU of 8p5d by Molmil
Spraguea lophii ribosome in the closed conformation by cryo sub tomogram averaging
分子名称: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ...
著者Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B.
登録日2023-05-23
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (10.8 Å)
主引用文献CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state.
Nat Microbiol, 8, 2023
8P60
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Spraguea lophii ribosome dimer
分子名称: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
著者Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B.
登録日2023-05-24
公開日2023-06-21
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (14.3 Å)
主引用文献CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state.
Nat Microbiol, 8, 2023
8P2K
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Ternary complex of translating ribosome, NAC and METAP1
分子名称: 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ...
著者Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N.
登録日2023-05-16
公開日2023-07-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献NAC controls cotranslational N-terminal methionine excision in eukaryotes.
Science, 380, 2023
5JVG
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BU of 5jvg by Molmil
The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ...
著者Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A.
登録日2016-05-11
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.428 Å)
主引用文献Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JTE
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BU of 5jte by Molmil
Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N.
登録日2016-05-09
公開日2016-07-20
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
8Q5I
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BU of 8q5i by Molmil
Structure of Candida albicans 80S ribosome in complex with cephaeline
分子名称: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ...
著者Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M.
登録日2023-08-09
公開日2023-09-13
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy
Biopolym Cell, 2023
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Wieland, M, Wilson, D.N.
登録日2020-02-26
公開日2020-07-01
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6YLY
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BU of 6yly by Molmil
pre-60S State NE2 (TAP-Flag-Nop53)
分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
6Y2L
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BU of 6y2l by Molmil
Structure of human ribosome in POST state
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
著者Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A.
登録日2020-02-16
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Cell Rep, 31, 2020
5JUT
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Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A.
登録日2016-05-10
公開日2016-10-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Elife, 5, 2016
6YJ4
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BU of 6yj4 by Molmil
Structure of Yarrowia lipolytica complex I at 2.7 A
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ...
著者Hirst, J, Grba, D.
登録日2020-04-02
公開日2020-08-12
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Nat.Struct.Mol.Biol., 27, 2020
6YLX
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BU of 6ylx by Molmil
pre-60S State NE1 (TAP-Flag-Nop53)
分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
6YLG
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BU of 6ylg by Molmil
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kater, L, Beckmann, R.
登録日2020-04-07
公開日2020-07-29
最終更新日2020-09-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Mol.Cell, 79, 2020
5KCS
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BU of 5kcs by Molmil
Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin, mRNA, TetM and P-site tRNA at 3.9A resolution
分子名称: (2R,3R,4R,6S)-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7S,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-({(2R,3aS,3a'R,6S,7R,7'R,7aS,7a'S)-7'-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-7-hydroxyoctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4',7-dihydroxy-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-4-{[(2R,4S,5R,6S)-5-methoxy-4,6-dimethyl-4-nitrotetrahydro-2H-pyran-2-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N.
登録日2016-06-06
公開日2016-08-17
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
8PW7
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BU of 8pw7 by Molmil
A respirasome from murine liver
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Vercellino, I, Sazanov, L.A.
登録日2023-07-19
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW5
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BU of 8pw5 by Molmil
CS respirasome from murine liver
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Vercellino, I, Sazanov, L.A.
登録日2023-07-19
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8PW6
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C respirasome from murine liver
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Vercellino, I, Sazanov, L.A.
登録日2023-07-19
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献SCAF1 drives the compositional diversity of mammalian respirasomes.
Nat.Struct.Mol.Biol., 2024
8QCQ
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BU of 8qcq by Molmil
B. subtilis ApdA-stalled ribosomal complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Morici, M, Wilson, D.N.
登録日2023-08-28
公開日2024-03-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
8Q0O
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Outward-facing, open2 proteoliposome complex I at 3.1 A. Initially purified in DDM.
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Grba, D.N, Hirst, J.
登録日2023-07-28
公開日2024-06-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I.
Science, 384, 2024
8Q46
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Inward-facing, open2 proteoliposome complex I at 2.6 A. Initially purified in LMNG.
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
著者Grba, D.N, Hirst, J.
登録日2023-08-05
公開日2024-06-05
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I.
Science, 384, 2024

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件を2024-08-07に公開中

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