PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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3UOT	Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus 分子名称: Mediator of DNA damage checkpoint protein 1 著者 Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. 登録日 2011-11-17 公開日 2011-12-28 最終更新日 2012-07-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
4OOI	Reduced HlyU from Vibrio cholerae N16961 分子名称: Transcriptional activator HlyU 著者 Mukherjee, D, Datta, A.B, Chakrabarti, P. 登録日 2014-02-03 公開日 2014-12-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications Biochim.Biophys.Acta, 1844, 2014
4OVX	Crystal structure of Xylose isomerase domain protein from Planctomyces limnophilus DSM 3776 分子名称: 1,2-ETHANEDIOL, Xylose isomerase domain protein TIM barrel 著者 Chang, C, Bigelow, L, Endres, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-01-22 公開日 2014-02-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.253 Å) 主引用文献 Crystal structure of Xylose isomerase domain protein from Planctomyces limnophilus DSM 3776 To be published
3UGC	Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594 分子名称: 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1H-indole-1-carboxamide, MALONATE ION, Tyrosine-protein kinase JAK2 著者 Scheufler, C, Tavares, G.A, Manley, P.W, Pissot-Soldermann, C, Kroemer, M. 登録日 2011-11-02 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Modulation of activation-loop phosphorylation by JAK inhibitors is binding mode dependent. Cancer Discov, 2, 2012
4OOU	Crystal structure of beta-1,4-D-mannanase from Cryptopygus antarcticus 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-1,4-mannanase 著者 Kim, M.-K, An, Y.J, Jeong, C.-S, Cha, S.-S. 登録日 2014-02-04 公開日 2014-08-06 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structure-based investigation into the functional roles of the extended loop and substrate-recognition sites in an endo-beta-1,4-d-mannanase from the Antarctic springtail, Cryptopygus antarcticus. Proteins, 82, 2014
3UP2	Aurora A in complex with RPM1686 分子名称: 1,2-ETHANEDIOL, 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2011-11-17 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3001 Å) 主引用文献 A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A. Acs Chem.Biol., 7, 2012
4OW4	Beta-trefoil designed by folding nucleus symmetric expansion ("Phifoil") 分子名称: Beta-terfoil designed by folding nucleus symmetric expansion ("Phifoil"), SULFATE ION 著者 Blaber, M, Longo, L.M. 登録日 2014-01-31 公開日 2014-12-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.148 Å) 主引用文献 Evolution and design of protein structure by folding nucleus symmetric expansion. Structure, 22, 2014
3UGO	Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT) 分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2011-11-02 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit. Cell(Cambridge,Mass.), 147, 2011
4OWA	Carboplatin binding to HEWL under sodium iodide crystallisation conditions 分子名称: ACETATE ION, DIMETHYL SULFOXIDE, IODIDE ION, ... 著者 Tanley, S.W.M, Helliwell, J.R. 登録日 2014-01-31 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.796 Å) 主引用文献 Chemical conversion of cisplatin and carboplatin with histidine in a model protein crystallized under sodium iodide conditions. Acta Crystallogr.,Sect.F, 70, 2014
4OPP	Crystal structure of the ternary complex of camel peptidoglycan recognition protein PGRP-S with 11-cyclohexylundecanoic acid and N- acetylglucosamine at 2.30 A resolution 分子名称: 11-cyclohexylundecanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Yamini, S, Sharma, P, Yadav, S.P, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2014-02-06 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the ternary complex of camel peptidoglycan recognition protein PGRP-S with 11-cyclohexylundecanoic acid and N- acetylglucosamine at 2.30 A resolution To be Published
3UPG	Loop deletion mutant of Salmonella typhi osmoporin (OmpC):an Outer Membrane Protein. 分子名称: CALCIUM ION, CHLORIDE ION, Outer membrane protein C 著者 Prasanth, P, Putcha, B.K, Arockiasamy, A, Krishnaswamy, S. 登録日 2011-11-18 公開日 2012-11-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of osmoporin (OmpC) loop deletion mutant: an Outer membrane protein from Salmonella typhi. To be Published
3UGT	Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase - orthorhombic crystal form 分子名称: Threonyl-tRNA synthetase, mitochondrial, ZINC ION 著者 Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M. 登録日 2011-11-02 公開日 2012-02-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proc.Natl.Acad.Sci.USA, 109, 2012
4OPY	Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation 分子名称: CALCIUM ION, Extended spectrum beta-lactamase TEM-63, SULFATE ION, ... 著者 Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. 登録日 2014-02-07 公開日 2015-05-20 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
4GJX	Crystal structure of CD23 lectin domain mutant D258A 分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor 著者 Yuan, D, Sutton, B.J, Dhaliwal, B. 登録日 2012-08-10 公開日 2013-06-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288, 2013
4OWM	Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 3-fluoroanthranilate, PRPP and Magnesium 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 2-azanyl-3-fluoranyl-benzoic acid, Anthranilate phosphoribosyltransferase, ... 著者 Castell, A, Cookson, T.V.M, Short, F.L, Lott, J.S. 登録日 2014-02-02 公開日 2014-04-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461, 2014
3UPN	Structure of penicillin-binding protein A from M. tuberculosis: imipenem acyl-enzyme complex 分子名称: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Penicillin-binding protein A 著者 Davies, C, Fedorovich, A. 登録日 2011-11-18 公開日 2012-10-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis J.Mol.Biol., 418, 2012
2R9M	Cathepsin S complexed with Compound 15 分子名称: Cathepsin S, N-[(1S)-2-[(4-cyano-1-methylpiperidin-4-yl)amino]-1-(cyclohexylmethyl)-2-oxoethyl]morpholine-4-carboxamide 著者 Ward, Y.D, Emmanuel, M.J, Thomson, D.S, Liu, W, Bekkali, Y, Frye, L.L, Girardot, M, Morwick, T, Young, E.R.R, Zindell, R, Hrapchak, M, DeTuri, M, White, A, Crane, K.M, White, D.M, Wang, Y, Hao, M.-H, Grygon, C.A, Labadia, M.E, Wildeson, J, Freeman, D, Nelson, R, Capolino, A, Peterson, J.D, Raymond, E.L, Brown, M.L, Spero, D.M. 登録日 2007-09-13 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Design and Synthesis of Reversible Inhibitors of Cathepsin S: alpha,alpha-Disubstitution at the P1 Residue Provides Potent Inhibitors in Cellular Assays and In Vivo Models of Antigen Presentation To be Published
4OX2	I45T cytosolic phosphoenolpyruvate carboxykinase in complex with beta-sulfopyruvate and GTP 分子名称: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Holyoak, T. 登録日 2014-02-04 公開日 2014-06-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity. Mol.Genet.Metab., 113, 2014
3UHS	HBI (L36M) deoxy 分子名称: Globin-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. 登録日 2011-11-03 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
4OQ4	Crystal Structure of E18A Human DJ-1 分子名称: Protein DJ-1, SODIUM ION 著者 Prahlad, J, Hauser, D.N, Milkovic, N.M, Cookson, M.R, Wilson, M.A. 登録日 2014-02-07 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers. J Neurochem, 130, 2014
4OQF	Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIB-SR 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein RecA 著者 Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M. 登録日 2014-02-09 公開日 2015-03-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability J.Biosci., 40, 2015
3URG	The crystal structure of Anabaena CcbP 分子名称: 5-MERCAPTO-2-NITRO-BENZOIC ACID, Alr1010 protein, SODIUM ION 著者 Fan, X.X, Liu, X, Su, X.D. 登録日 2011-11-22 公開日 2012-11-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Ellman's reagent in promoting crystallization and structure determination of Anabaena CcbP. Acta Crystallogr.,Sect.F, 68, 2012
3UI2	Crystal structure of the cpSRP54 tail bound to cpSRP43 分子名称: Signal recognition particle 43 kDa protein, chloroplastic, Signal recognition particle 54 kDa protein 著者 Holdermann, I, Wild, K, Sinning, I. 登録日 2011-11-04 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.178 Å) 主引用文献 Chromodomains read the arginine code of post-translational targeting. Nat.Struct.Mol.Biol., 19, 2012
4OYA	Human solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone 分子名称: (4-azanyl-1,2,5-oxadiazol-3-yl)-[3-(1H-benzimidazol-2-ylmethoxy)phenyl]methanone, Adenylate cyclase type 10, GLYCEROL 著者 Vinkovic, M. 登録日 2014-02-11 公開日 2014-04-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
4OQO	Crystal structure of the tryptic generated iron-free C-lobe of bovine Lactoferrin at 2.42 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lactotransferrin 著者 Singh, A, Rastogi, N, Pandey, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2014-02-10 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut. Febs J., 281, 2014

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