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4OX2

I45T cytosolic phosphoenolpyruvate carboxykinase in complex with beta-sulfopyruvate and GTP

Summary for 4OX2
Entry DOI10.2210/pdb4ox2/pdb
DescriptorPhosphoenolpyruvate carboxykinase, cytosolic [GTP], MANGANESE (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... (8 entities in total)
Functional Keywordskinase, gluconeogenesis, lyase
Biological sourceRattus norvegicus (Rat)
Total number of polymer chains2
Total formula weight141300.11
Authors
Holyoak, T. (deposition date: 2014-02-04, release date: 2014-06-11, Last modification date: 2023-09-27)
Primary citationAdams, D.R.,Yuan, H.,Holyoak, T.,Arajs, K.H.,Hakimi, P.,Markello, T.C.,Wolfe, L.A.,Vilboux, T.,Burton, B.K.,Fajardo, K.F.,Grahame, G.,Holloman, C.,Sincan, M.,Smith, A.C.,Wells, G.A.,Huang, Y.,Vega, H.,Snyder, J.P.,Golas, G.A.,Tifft, C.J.,Boerkoel, C.F.,Hanson, R.W.,Traynelis, S.F.,Kerr, D.S.,Gahl, W.A.
Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity.
Mol.Genet.Metab., 113:161-170, 2014
Cited by
PubMed: 24863970
DOI: 10.1016/j.ymgme.2014.04.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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