4OX2
I45T cytosolic phosphoenolpyruvate carboxykinase in complex with beta-sulfopyruvate and GTP
Summary for 4OX2
Entry DOI | 10.2210/pdb4ox2/pdb |
Descriptor | Phosphoenolpyruvate carboxykinase, cytosolic [GTP], MANGANESE (II) ION, GUANOSINE-5'-TRIPHOSPHATE, ... (8 entities in total) |
Functional Keywords | kinase, gluconeogenesis, lyase |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 2 |
Total formula weight | 141300.11 |
Authors | Holyoak, T. (deposition date: 2014-02-04, release date: 2014-06-11, Last modification date: 2023-09-27) |
Primary citation | Adams, D.R.,Yuan, H.,Holyoak, T.,Arajs, K.H.,Hakimi, P.,Markello, T.C.,Wolfe, L.A.,Vilboux, T.,Burton, B.K.,Fajardo, K.F.,Grahame, G.,Holloman, C.,Sincan, M.,Smith, A.C.,Wells, G.A.,Huang, Y.,Vega, H.,Snyder, J.P.,Golas, G.A.,Tifft, C.J.,Boerkoel, C.F.,Hanson, R.W.,Traynelis, S.F.,Kerr, D.S.,Gahl, W.A. Three rare diseases in one Sib pair: RAI1, PCK1, GRIN2B mutations associated with Smith-Magenis Syndrome, cytosolic PEPCK deficiency and NMDA receptor glutamate insensitivity. Mol.Genet.Metab., 113:161-170, 2014 Cited by PubMed: 24863970DOI: 10.1016/j.ymgme.2014.04.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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