PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4CCN	60S ribosomal protein L8 histidine hydroxylase (NO66 L299C/C300S) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G220C) peptide fragment (complex-2) 分子名称: 1,2-ETHANEDIOL, 60S RIBOSOMAL PROTEIN L8, BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2013-10-23 公開日 2014-05-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510, 2014
3CAS	Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 4-androstenedione 分子名称: 1,2-ETHANEDIOL, 3-oxo-5-beta-steroid 4-dehydrogenase, 4-ANDROSTENE-3-17-DIONE, ... 著者 Faucher, F, Cantin, L, Breton, R. 登録日 2008-02-20 公開日 2008-12-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of Human Delta4-3-Ketosteroid 5beta-Reductase (AKR1D1) Reveal the Presence of an Alternative Binding Site Responsible for Substrate Inhibition (dagger) (,) (double dagger). Biochemistry, 47, 2008
1L8A	E. COLI PYRUVATE DEHYDROGENASE 分子名称: MAGNESIUM ION, Pyruvate dehydrogenase E1 component, THIAMINE DIPHOSPHATE 著者 Furey, W, Arjunan, P. 登録日 2002-03-19 公開日 2002-07-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution. Biochemistry, 41, 2002
4NJO	crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in Entamoeba histolytica 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-3-phosphoglycerate dehydrogenase, putative, ... 著者 Singh, R.K, Gourinath, S. 登録日 2013-11-11 公開日 2014-10-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine. Febs J., 281, 2014
5IVJ	Linked KDM5A Jmj Domain Bound to the Inhibitor N11 [3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid] 分子名称: 3-({1-[2-(4,4-difluoropiperidin-1-yl)ethyl]-5-fluoro-1H-indazol-3-yl}amino)pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2016-03-21 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.569 Å) 主引用文献 Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol, 23, 2016
5IWE	E45Q mutant of phenazine biosynthesis protein PhzF in complex with (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate 分子名称: (5R,6R)-6-azaniumyl-5-ethoxycyclohexa-1,3-diene-1-carboxylate, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... 著者 Diederich, C, Blankenfeldt, W. 登録日 2016-03-22 公開日 2017-03-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Mechanisms and Specificity of Phenazine Biosynthesis Protein PhzF. Sci Rep, 7, 2017
7CZI	Structure of the CYP102A1 Haem Domain with N-{2-[4-(Trifluoromethoxy)phenoxy]}acetoyl-L-Phenylalanine 分子名称: (2S)-3-phenyl-2-[2-[4-(trifluoromethyloxy)phenoxy]ethanoylamino]propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, DIMETHYL SULFOXIDE, ... 著者 Stanfield, J.K, Sugimoto, H, Shoji, O. 登録日 2020-09-08 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structure of the CYP102A1 Haem Domain with N-{2-[4-(Trifluoromethoxy)phenoxy]}acetoyl-L-Phenylalanine at 1.64 Angstrom Resolution To Be Published
1QU9	1.2 A CRYSTAL STRUCTURE OF YJGF GENE PRODUCT FROM E. COLI 分子名称: YJGF PROTEIN 著者 Volz, K. 登録日 1999-07-07 公開日 1999-12-01 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 A test case for structure-based functional assignment: the 1.2 A crystal structure of the yjgF gene product from Escherichia coli Protein Sci., 8, 1999
3ZQA	CRYSTALLOGRAPHIC STRUCTURE OF BETAINE ALDEHYDE DEHYDROGENASE MUTANT C286A FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH NADPH 分子名称: 1,2-ETHANEDIOL, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, BETAINE ALDEHYDE DEHYDROGENASE, ... 著者 Diaz-Sanchez, A.G, Gonzalez-Segura, L, Rudino-Pinera, E, Lira-Rocha, A, Torres-Larios, A, Munoz-Clares, R.A. 登録日 2011-06-08 公開日 2011-10-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Novel Nadph-Cysteine Covalent Adduct Found in the Active Site of an Aldehyde Dehydrogenase. Biochem.J., 439, 2011
6LTR	Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket 分子名称: 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... 著者 Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. 登録日 2020-01-23 公開日 2020-10-28 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
5CVE	Crystal Structure of human NRMT1 in complex with dimethylated fly H2B peptide and SAH 分子名称: N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminal peptide from Histone H2B, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wu, R, Li, H. 登録日 2015-07-26 公開日 2015-11-25 最終更新日 2025-04-09 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular basis for histone N-terminal methylation by NRMT1 Genes Dev., 29, 2015
4O1Q	Crystal Structure of the Q103N-MauG/pre-Methylamine Dehydrogenase Complex 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Yukl, E.T, Wilmot, C.W. 登録日 2013-12-16 公開日 2014-04-30 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Site-directed mutagenesis of Gln103 reveals the influence of this residue on the redox properties and stability of MauG. Biochemistry, 53, 2014
4ILK	Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MANGANESE (II) ION, Starvation sensing protein rspB, ... 著者 Lukk, T, Wichelecki, D, Imker, H.J, Gerlt, J.A, Nair, S.K. 登録日 2012-12-31 公開日 2013-01-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Crystal structure of short chain alcohol dehydrogenase (rspB) from E. coli CFT073 (EFI TARGET EFI-506413) complexed with cofactor NADH To be Published
2VHZ	Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the closed conformation 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALANINE DEHYDROGENASE 著者 Agren, D, Schneider, G. 登録日 2007-11-26 公開日 2008-03-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding. J.Mol.Biol., 377, 2008
4R41	Complex Crystal structure of 4-nitro-2-phosphono-benzoic acid with sp-Aspartate-Semialdehyde Dehydrogenase and Nicotinamide-dinucleotide 分子名称: 1,2-ETHANEDIOL, 4-nitro-2-phosphonobenzoic acid, ACETATE ION, ... 著者 Pavlovsky, A.G, Viola, R.E. 登録日 2014-08-18 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway. Acta Crystallogr.,Sect.D, 70, 2014
3T0G	IspH:HMBPP (substrate) structure of the T167C mutant 分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, FE3-S4 CLUSTER 著者 Span, I, Graewert, T, Bacher, A, Eisenreich, W, Groll, M. 登録日 2011-07-20 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of Mutant IspH Proteins Reveal a Rotation of the Substrate's Hydroxymethyl Group during Catalysis. J.Mol.Biol., 416, 2012
5GGF	Crystal structure of human protein O-mannose beta-1,2-N-acetylglucosaminyltransferase form II 分子名称: Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 著者 Kuwabara, N, Senda, T, Kato, R. 登録日 2016-06-15 公開日 2016-08-10 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan Proc.Natl.Acad.Sci.USA, 113, 2016
2VHW	Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the open and closed conformation 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALANINE DEHYDROGENASE, MAGNESIUM ION 著者 Agren, D, Schneider, G. 登録日 2007-11-26 公開日 2008-03-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding. J.Mol.Biol., 377, 2008
2VAO	STRUCTURE OF THE OCTAMERIC FLAVOENZYME VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL 分子名称: 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE 著者 Mattevi, A. 登録日 1997-04-10 公開日 1997-10-15 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures and inhibitor binding in the octameric flavoenzyme vanillyl-alcohol oxidase: the shape of the active-site cavity controls substrate specificity. Structure, 5, 1997
4R51	Crystal complex structure of sp-Aspartate-Semialdehyde-Dehydrogenase with Nicotinamide Adenine dinucleotide phosphate and phthalic acid 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aspartate-semialdehyde dehydrogenase, ... 著者 Pavlovsky, A.G, Viola, R.E. 登録日 2014-08-20 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway. Acta Crystallogr.,Sect.D, 70, 2014
3IBO	Pseudomonas aeruginosa E2Q/H83Q/T126H-azurin RE(PHEN)(CO)3 分子名称: (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION 著者 Gradinaru, C, Crane, B.R, Sudhamsu, J. 登録日 2009-07-16 公開日 2009-12-08 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Relaxation dynamics of Pseudomonas aeruginosa Re(I)(CO)3(alpha-diimine)(HisX)+ (X = 83, 107, 109, 124, 126)Cu(II) azurins. J.Am.Chem.Soc., 131, 2009
6M5X	A fungal glyceraldehyde-3-phosphate dehydrogenase with self-resistance to inhibitor heptelidic acid 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Yan, Y, Zang, X, Cooper, S.J, Lin, H, Zhou, J, Tang, Y. 登録日 2020-03-12 公開日 2020-12-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.05990934 Å) 主引用文献 Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance Chem Sci, 11, 2020
6LY4	The crystal structure of the BM3 mutant LG-23 in complex with testosterone 分子名称: 1,2-ETHANEDIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, IMIDAZOLE, ... 著者 Peng, Y, Chen, J, Zhou, J, Li, A, ReetZ, M.T. 登録日 2020-02-13 公開日 2020-04-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Regio- and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants. Angew.Chem.Int.Ed.Engl., 59, 2020
4BL5	Crystal structure of human GDP-L-fucose synthase with bound NADP and product GDP-L-fucose 分子名称: 1,2-ETHANEDIOL, GDP-L-FUCOSE SYNTHASE, GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE, ... 著者 Vollmar, M, Shafqat, N, Rojkova, A, Krojer, T, Bradley, A, Raynor, J.W, Kavanagh, K, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U, Yue, W.W. 登録日 2013-05-01 公開日 2014-05-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Product Gdp-L-Fucose To be Published
5ZE0	Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ 分子名称: 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ... 著者 Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. 登録日 2018-02-25 公開日 2018-04-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018

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