6M5X

A fungal glyceraldehyde-3-phosphate dehydrogenase with self-resistance to inhibitor heptelidic acid

Summary for 6M5X

• Entry DOI: 10.2210/pdb6m5x/pdb
• Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, 1,2-ETHANEDIOL, GLYCEROL, ... (7 entities in total)
• Functional Keywords: inhibitor, self-resistance, heptelidic acid, oxidoreductase
• Biological source: Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens)
• Total number of polymer chains: 4
• Total formula weight: 149426.32

Authors

Yan, Y.,Zang, X.,Cooper, S.J.,Lin, H.,Zhou, J.,Tang, Y. (deposition date: 2020-03-12, release date: 2020-12-30, Last modification date: 2023-11-29)

• Primary citation: Yan, Y.,Zang, X.,Cooper, S.J.,Lin, H.,Zhou, J.,Tang, Y.; Biosynthesis of the fungal glyceraldehyde-3-phosphate dehydrogenase inhibitor heptelidic acid and mechanism of self-resistance; Chem Sci, 11:9554-9562, 2020; DOI: 10.1039/D0SC03805A

Experimental method

X-RAY DIFFRACTION (2.05990923752 Å)