PDB: 55698 件ウェブページステータス検索Chemie searchBIRD

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6QIO	Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the human growth hormone derivative somapacitan 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, CYSTEINE, ... 著者 Johansson, E. 登録日 2019-01-21 公開日 2020-02-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative. Biochemistry, 59, 2020
7PZN	wt HBc capsid like particles in complex with inhibitory peptide SLLGRM and Triton X-100 分子名称: Capsid protein, FRAGMENT OF TRITON X-100, SLLGRM, ... 著者 Makbul, C, Boettcher, B. 登録日 2021-10-12 公開日 2021-12-08 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Binding of a Pocket Factor to Hepatitis B Virus Capsids Changes the Rotamer Conformation of Phenylalanine 97. Viruses, 13, 2021
7PA0	NaK C-DI F92A mutant with Rb+ and K+ 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... 著者 Minniberger, S, Plested, A.J.R. 登録日 2021-07-28 公開日 2022-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
7R1U	Crystal structure of SARS-CoV-2 nsp10/nsp16 in complex with the WZ16 inhibitor 分子名称: (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Klima, M, Boura, E, Li, F, Yazdi, A.K, Vedadi, M. 登録日 2022-02-03 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16. Protein Sci., 31, 2022
3SCV	Crystal Structure of Rice BGlu1 E386G/S334A Mutant Complexed with Cellotetraose 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-glucosidase 7, SULFATE ION, ... 著者 Pengthaisong, S, Withers, S.G, Kuaprasert, B, Ketudat Cairns, J.R. 登録日 2011-06-08 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural investigation of the basis for cellooligosaccharide synthesis by rice BGlu1 glycosynthases to be published
2PGH	STRUCTURE DETERMINATION OF AQUOMET PORCINE HEMOGLOBIN AT 2.8 ANGSTROM RESOLUTION 分子名称: HEMOGLOBIN (AQUO MET) (ALPHA CHAIN), HEMOGLOBIN (AQUO MET) (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE 著者 Katz, D.S, White, S.P, Huang, W, Kumar, R, Christianson, D.W. 登録日 1994-09-16 公開日 1994-11-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure determination of aquomet porcine hemoglobin at 2.8 A resolution. J.Mol.Biol., 244, 1994
1NHQ	CRYSTALLOGRAPHIC ANALYSES OF NADH PEROXIDASE CYS42ALA AND CYS42SER MUTANTS: ACTIVE SITE STRUCTURE, MECHANISTIC IMPLICATIONS, AND AN UNUSUAL ENVIRONMENT OF ARG303 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH PEROXIDASE, SULFATE ION 著者 Mande, S.S, Claiborne, A, Hol, W.G.J. 登録日 1994-12-09 公開日 1995-02-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic analyses of NADH peroxidase Cys42Ala and Cys42Ser mutants: active site structures, mechanistic implications, and an unusual environment of Arg 303. Biochemistry, 34, 1995
7QZX	Human Carbonic Anhydrase II in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carboxamide 分子名称: 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carboxamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Angeli, A, Ferraroni, M. 登録日 2022-02-01 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37, 2022
7R1X	human Carbonic Anhydrase II in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide 分子名称: 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Angeli, A, Ferraroni, M. 登録日 2022-02-03 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37, 2022
4KI2	Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA 分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2013-05-01 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr.,Sect.F, 69, 2013
6CNN	Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, Calmodulin-1, ... 著者 Lee, C.H, MacKinnon, R. 登録日 2018-03-08 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science, 360, 2018
1GT7	L-rhamnulose-1-phosphate aldolase from Escherichia coli 分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, RHAMNULOSE-1-PHOSPHATE ALDOLASE, ZINC ION 著者 Kroemer, M, Schulz, G.E. 登録日 2002-01-14 公開日 2002-05-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Structure of L-Rhamnulose-1-Phosphate Aldolase (Class II) Solved by Low-Resolution Sir Phasing and 20-Fold Ncs Averaging Acta Crystallogr.,Sect.D, 58, 2002
3O8G	EthR from Mycobacterium tuberculosis in complex with compound BDM14801 分子名称: 1-(azidoacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR 著者 Willand, N, Desroses, M, Toto, P, Diri, B, Lens, Z, Villeret, V, Rucktooa, P, Locht, C, Baulard, A, Deprez, B. 登録日 2010-08-03 公開日 2010-09-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploring drug target flexibility using in situ click chemistry: application to a mycobacterial transcriptional regulator. Acs Chem.Biol., 5, 2010
6BRG	The SAM domain of mouse SAMHD1 is critical for its activation and regulation 分子名称: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION 著者 Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y. 登録日 2017-11-30 公開日 2018-02-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun, 9, 2018
7M7I	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2 (TE-free) 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI, ... 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
5HV8	Solution structure of an octanoyl- loaded acyl carrier protein domain from module MLSA2 of the mycolactone polyketide synthase. 分子名称: S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate, Type I modular polyketide synthase 著者 Vance, S, Tkachenko, O, Thomas, B, Bassuni, M, Hong, H, Nietlispach, D, Broadhurst, R.W. 登録日 2016-01-28 公開日 2016-03-09 最終更新日 2019-10-23 実験手法 SOLUTION NMR 主引用文献 Sticky swinging arm dynamics: studies of an acyl carrier protein domain from the mycolactone polyketide synthase. Biochem.J., 473, 2016
7M7J	6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: "turnstile closed" state (TE-free) 分子名称: 1B2 (heavy chain), 1B2 (light chain), EryAI 著者 Cogan, D.P, Zhang, K, Chiu, W, Khosla, C. 登録日 2021-03-28 公開日 2021-11-17 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Mapping the catalytic conformations of an assembly-line polyketide synthase module. Science, 374, 2021
6DHZ	Crystallographic octamer of a metal-free RIDC1 variant bearing two disulfide bonded cysteines 分子名称: CALCIUM ION, HEME C, Soluble cytochrome b562 著者 Tezcan, F.A, Churchfield, L.A. 登録日 2018-05-21 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Determining the Structural and Energetic Basis of Allostery in a De Novo Designed Metalloprotein Assembly. J. Am. Chem. Soc., 140, 2018
4MO7	Crystal structure of superantigen PfiT 分子名称: BETA-MERCAPTOETHANOL, MAGNESIUM ION, Transcriptional regulator I2 著者 Liu, L.H, Chen, H, Li, H.M. 登録日 2013-09-11 公開日 2014-02-05 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Pfit is a structurally novel Crohn's disease-associated superantigen. Plos Pathog., 9, 2013
5VSW	X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-05-12 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.295 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
5V7I	Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile 分子名称: (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. 登録日 2017-03-20 公開日 2017-10-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3N75	X-ray Crystal Structure of the Escherichia coli Inducible Lysine Decarboxylase LdcI 分子名称: GLYCEROL, GUANOSINE-5',3'-TETRAPHOSPHATE, HEXAETHYLENE GLYCOL, ... 著者 Kanjee, U, Alexopoulos, E, Pai, E.F, Houry, W.A. 登録日 2010-05-26 公開日 2011-02-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase. Embo J., 30, 2011
6DMC	ppGpp Riboswitch bound to ppGpp, native structure 分子名称: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Peselis, A, Serganov, A. 登録日 2018-06-04 公開日 2018-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
6D7R	Crystal structure of an inactivate variant of the quorum-sensing master regulator HapR from protease-deficient non-O1, non-O139 Vibrio cholerae strain V2 分子名称: Hemagglutinin/protease regulatory protein 著者 Cruite, J.T, Succo, P, Raychaudhuri, S, Kull, F.J. 登録日 2018-04-25 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of an inactive variant of the quorum-sensing master regulator HapR from the protease-deficient non-O1, non-O139 Vibrio cholerae strain V2. Acta Crystallogr F Struct Biol Commun, 74, 2018
3H1R	Order-disorder structure of fluorescent protein FP480 分子名称: Fluorescent protein FP480 著者 Pletnev, S, Morozova, K.S, Verkhusha, V.V, Dauter, Z. 登録日 2009-04-13 公開日 2009-09-08 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Rotational order-disorder structure of fluorescent protein FP480 Acta Crystallogr.,Sect.D, 65, 2009

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