6Z4C
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![BU of 6z4c by Molmil](/molmil-images/mine/6z4c) | The structure of the N-terminal domain of RssB from E. coli | 分子名称: | Regulator of RpoS | 著者 | Zeth, K, Dimce, M, Terrence, D.M, Schuenemann, V, Dougan, D. | 登録日 | 2020-05-25 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insight into the RssB-Mediated Recognition and Delivery of sigma s to the AAA+ Protease, ClpXP. Biomolecules, 10, 2020
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4ZTV
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![BU of 4ztv by Molmil](/molmil-images/mine/4ztv) | Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP | 分子名称: | 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione, Anthranilate phosphoribosyltransferase | 著者 | Evans, G.L, Eom, J, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-05-15 | 公開日 | 2016-05-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Bioactive non-anthranilate-like fragment-like inhibitor provides alternative starting point for inhibitor design against anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis. To be Published
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4QPI
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![BU of 4qpi by Molmil](/molmil-images/mine/4qpi) | Crystal structure of hepatitis A virus | 分子名称: | CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2014-06-23 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
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5LRP
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![BU of 5lrp by Molmil](/molmil-images/mine/5lrp) | Mopeia Virus Exonuclease domain complexed with Magnesium | 分子名称: | MAGNESIUM ION, Nucleoprotein, ZINC ION | 著者 | Yekwa, E.L, Khourieh, J, Canard, B, Ferron, F. | 登録日 | 2016-08-19 | 公開日 | 2017-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.941 Å) | 主引用文献 | Activity inhibition and crystal polymorphism induced by active-site metal swapping. Acta Crystallogr D Struct Biol, 73, 2017
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6NBS
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![BU of 6nbs by Molmil](/molmil-images/mine/6nbs) | WT ERK2 with compound 2507-8 | 分子名称: | (5S)-5-benzyl-4,5-dihydro-1H-imidazol-2-amine, GLYCEROL, Mitogen-activated protein kinase 1, ... | 著者 | Sammons, R.M, Perry, N.A, Cho, E.J, Kaoud, T.S, Zamora-Olivares, D.P, Piserchio, A, Houghten, R.A, Giulianotti, M, Li, Y, Debevec, G, Gurevich, V.V, Ghose, R, Iverson, T.M, Dalby, K.N. | 登録日 | 2018-12-10 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation. Acs Chem.Biol., 14, 2019
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5LVN
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![BU of 5lvn by Molmil](/molmil-images/mine/5lvn) | Human PDK1 Kinase Domain in Complex with Adenosine Bound to the ATP-Binding Site | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE, CHLORIDE ION, ... | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.379 Å) | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase. Cell Chem Biol, 23, 2016
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8JHH
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![BU of 8jhh by Molmil](/molmil-images/mine/8jhh) | Glycoside hydrolase family 55 endo-beta-1,3-glucanase from Microdochium nivale | 分子名称: | GLYCEROL, MnLam55A | 著者 | Ota, T, Saburi, W, Yamashita, K, Tagami, T, Yu, J, Komba, S, Jewell, L.E, Hsiang, T, Imai, R, Yao, M, Mori, H. | 登録日 | 2023-05-23 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular mechanism for endo-type action of glycoside hydrolase family 55 endo-beta-1,3-glucanase on beta 1-3/1-6-glucan. J.Biol.Chem., 299, 2023
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2UY7
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![BU of 2uy7 by Molmil](/molmil-images/mine/2uy7) | Crystal structure of the P pilus rod subunit PapA | 分子名称: | PAP FIMBRIAL MAJOR PILIN PROTEIN, PERIPLASMID CHAPERONE PAPD PROTEIN, SULFATE ION | 著者 | Verger, D, Bullitt, E, Hultgren, S.J, Waksman, G. | 登録日 | 2007-04-02 | 公開日 | 2007-05-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of the P Pilus Rod Subunit Papa. Plos Pathog., 3, 2007
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5UBI
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![BU of 5ubi by Molmil](/molmil-images/mine/5ubi) | Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound PRPP | 分子名称: | 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ACETATE ION, ... | 著者 | Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J. | 登録日 | 2016-12-20 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochem. J., 475, 2018
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6TLI
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![BU of 6tli by Molmil](/molmil-images/mine/6tli) | THERMOLYSIN (60% ISOPROPANOL SOAKED CRYSTALS) | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ... | 著者 | English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E. | 登録日 | 1998-10-29 | 公開日 | 2000-03-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol. Proteins, 37, 1999
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5NZQ
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![BU of 5nzq by Molmil](/molmil-images/mine/5nzq) | Crystal structure of human 3-phosphoglycerate dehydrogenase in complex with 3-(1,3-oxazol-5-yl)aniline. | 分子名称: | 3-(1,3-oxazol-5-yl)aniline, D-3-phosphoglycerate dehydrogenase | 著者 | Unterlass, J.E, Basle, A, Blackburn, T.J, Tucker, J, Cano, C, Noble, M.E.M, Curtin, N.J. | 登録日 | 2017-05-14 | 公開日 | 2017-06-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer. Oncotarget, 9, 2018
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1NZQ
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![BU of 1nzq by Molmil](/molmil-images/mine/1nzq) | D-Phe-Pro-Arg-Type Thrombin Inhibitor | 分子名称: | (2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-3-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL} -1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID, Decapeptide Hirudin Analogue, Thrombin heavy chain, ... | 著者 | Lange, U.E, Bauke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W. | 登録日 | 2003-02-19 | 公開日 | 2003-10-14 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety Bioorg.Med.Chem.Lett., 13, 2003
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6TBR
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![BU of 6tbr by Molmil](/molmil-images/mine/6tbr) | Glycosylated AA13 Lytic polysaccharide monooxygenase from Aspergillus oryzae in P1 space group | 分子名称: | AoAA13, ZINC ION | 著者 | Frandsen, K.E.H, Muderspach, S.J, Tandrup, T, Poulsen, J.C.N, Lo Leggio, L. | 登録日 | 2019-11-04 | 公開日 | 2020-03-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Further structural studies of the lytic polysaccharide monooxygenase AoAA13 belonging to the starch-active AA13 family Amylase, 3(1), 2019
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7LSF
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8J4R
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5A7M
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![BU of 5a7m by Molmil](/molmil-images/mine/5a7m) | The structure of Hypocrea jecorina beta-xylosidase Xyl3A (Bxl1) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mikkelsen, N.E, Gudmundsson, M, Karkehabadi, S, Hansson, H, Sandgren, M, Larenas, E, Mitchinson, C, Keleman, B, Kaper, T. | 登録日 | 2015-07-08 | 公開日 | 2016-08-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Th Crystal Structure of a Fungal Glycoside Hydrolase Family 3 Beta-Xylosidase, Xyl3A from Hypocrea Jecorina To be Published
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2UW1
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![BU of 2uw1 by Molmil](/molmil-images/mine/2uw1) | Ivy Desaturase Structure | 分子名称: | (3R)-3-HYDROXY-5,5-DIMETHYLHEXANOIC ACID, FE (III) ION, PLASTID DELTA4 MULTIFUNCTIONAL ACYL-ACYL CARRIER PROTEIN DESATURASE, ... | 著者 | Guy, J.E, Whittle, E, Kumaran, D, Lindqvist, Y, Shanklin, J. | 登録日 | 2007-03-15 | 公開日 | 2007-05-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Crystal Structure of the Ivy {Delta}4-16:0-Acp Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity. J.Biol.Chem., 282, 2007
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3ZWG
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![BU of 3zwg by Molmil](/molmil-images/mine/3zwg) | Crystal structure of the pore-forming toxin FraC from Actinia fragacea (form 2) | 分子名称: | FRAGACEATOXIN C | 著者 | Mechaly, A.E, Bellomio, A, Morante, K, Gonzalez-Manas, J.M, Guerin, D.M.A. | 登録日 | 2011-07-29 | 公開日 | 2012-07-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Pores of the Toxin Frac Assemble Into 2D Hexagonal Clusters in Both Crystal Structures and Model Membranes. J.Struct.Biol., 180, 2012
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4R1S
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![BU of 4r1s by Molmil](/molmil-images/mine/4r1s) | Crystal structure of Petunia hydrida cinnamoyl-CoA reductase | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, cinnamoyl CoA reductase | 著者 | Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K. | 登録日 | 2014-08-07 | 公開日 | 2014-10-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis. Plant Cell, 26, 2014
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5UBH
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![BU of 5ubh by Molmil](/molmil-images/mine/5ubh) | Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound ATP | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ATP phosphoribosyltransferase, ... | 著者 | Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J. | 登録日 | 2016-12-20 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochem. J., 475, 2018
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6TRY
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![BU of 6try by Molmil](/molmil-images/mine/6try) | Crystal structure of human Aldehyde dehydrogenase 1A3 in complex with MF13 inhibitor compound | 分子名称: | 8-(4-chlorophenyl)-2-phenyl-imidazo[1,2-a]pyridine, Aldehyde dehydrogenase family 1 member A3, GLYCEROL, ... | 著者 | Gelardi, E.L.M, Garavaglia, S. | 登録日 | 2019-12-19 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Progress in the Field of Aldehyde Dehydrogenase Inhibitors: Novel Imidazo[1,2- a ]pyridines against the 1A Family. Acs Med.Chem.Lett., 11, 2020
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3MZG
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![BU of 3mzg by Molmil](/molmil-images/mine/3mzg) | Crystal structure of a human prolactin receptor antagonist in complex with the extracellular domain of the human prolactin receptor | 分子名称: | CHLORIDE ION, Prolactin, Prolactin receptor, ... | 著者 | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | 登録日 | 2010-05-12 | 公開日 | 2010-09-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
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5M1C
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8TYO
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6NIE
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![BU of 6nie by Molmil](/molmil-images/mine/6nie) | BesD with Fe(II), chloride, and alpha-ketoglutarate | 分子名称: | 2-OXOGLUTARIC ACID, BesD, lysine halogenase, ... | 著者 | Neugebauer, M.E, Chang, M.C.Y. | 登録日 | 2018-12-27 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A family of radical halogenases for the engineering of amino-acid-based products. Nat.Chem.Biol., 15, 2019
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