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3MNN
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BU of 3mnn by Molmil
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
分子名称: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
著者Ong, M.S, Davey, C.A.
登録日2010-04-22
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
1DLO
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BU of 1dlo by Molmil
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
分子名称: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE
著者Hsiou, Y, Ding, J, Das, K, Hughes, S, Arnold, E.
登録日1996-04-17
公開日1996-08-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.
Structure, 4, 1996
8UH4
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BU of 8uh4 by Molmil
Cryo-EM structure of Maize Streak Virus (MSV) - single head Geminivirus
分子名称: Capsid protein, genomic DNA
著者Bennett, A.B, McKenna, R, Mietzsch, M, Hull, J.A.
登録日2023-10-06
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献The Two States of MSV Gemini Capsid Assembly
To Be Published
8UGQ
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BU of 8ugq by Molmil
CryoEM Structure of Maize Streak Virus (MSV) - Geminivirus
分子名称: Capsid protein, DNA (5'-D(P*CP*GP*AP*AP*CP*CP*CP*CP*A)-3')
著者McKenna, R, Bennett, A.B, Mietzsch, M, Hull, J.A.
登録日2023-10-05
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献The two states of Maize Streak Virus (MSV) Geminivirus Architecture
To Be Published
3DB4
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BU of 3db4 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1
分子名称: E3 ubiquitin-protein ligase UHRF1, SULFATE ION
著者Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-09-16
最終更新日2012-04-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
6JQ4
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BU of 6jq4 by Molmil
HIGA Escherichia coli-K12
分子名称: Antitoxin HigA
著者She, Z, Xu, B.S.
登録日2019-03-28
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational changes of antitoxin HigA from Escherichia coli str. K-12 upon binding of its cognate toxin HigB reveal a new regulation mechanism in toxin-antitoxin systems.
Biochem.Biophys.Res.Commun., 514, 2019
3F8T
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BU of 3f8t by Molmil
Crystal structure analysis of a full-length MCM homolog from Methanopyrus kandleri
分子名称: Predicted ATPase involved in replication control, Cdc46/Mcm family
著者Bae, B, Nair, S.K.
登録日2008-11-13
公開日2009-03-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the Architecture of the Replicative Helicase from the Structure of an Archaeal MCM Homolog.
Structure, 17, 2009
1ASU
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BU of 1asu by Molmil
AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE
著者Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A.
登録日1995-08-25
公開日1995-11-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
8QSJ
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BU of 8qsj by Molmil
Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7
分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Ritter, C, Nguyen, T.G, Kummer, E.
登録日2023-10-10
公開日2023-12-13
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Nat Commun, 14, 2023
8GLV
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BU of 8glv by Molmil
96-nm repeat unit of doublet microtubules from Chlamydomonas reinhardtii flagella
分子名称: 28 kDa inner dynein arm light chain, axonemal, AAA+ ATPase domain-containing protein, ...
著者Walton, T, Brown, A.
登録日2023-03-23
公開日2023-05-31
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
4DAY
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BU of 4day by Molmil
Crystal structure of the RMI core complex with MM2 peptide from FANCM
分子名称: Fanconi anemia group M protein, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2
著者Hoadley, K.A, Keck, J.L.
登録日2012-01-13
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome.
Proc.Natl.Acad.Sci.USA, 109, 2012
8DEY
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BU of 8dey by Molmil
Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2,3) and the molecular glue DKY709
分子名称: (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ...
著者Ma, X, Ornelas, E, Clifton, M.C.
登録日2022-06-21
公開日2023-03-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
Cell Chem Biol, 30, 2023
3ZVN
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BU of 3zvn by Molmil
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase
分子名称: 5'-D(*GP*TP*CP*AP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, ...
著者Garces, F, Pearl, L.H, Oliver, A.W.
登録日2011-07-25
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol. Cell, 44, 2011
7OF7
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BU of 7of7 by Molmil
Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 and GTPBP5 (dataset1).
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R.
登録日2021-05-04
公開日2021-06-23
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
7ODT
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BU of 7odt by Molmil
State C of the human mitoribosomal large subunit assembly intermediate
分子名称: 16S mitochondrial rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N.
登録日2021-04-30
公開日2021-06-23
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
8OO4
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BU of 8oo4 by Molmil
X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 1 month soaking
分子名称: AMMONIA, Angiogenin, PLATINUM (II) ION
著者Ferraro, G, Merlino, A.
登録日2023-04-04
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.
Dalton Trans, 52, 2023
7OIC
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BU of 7oic by Molmil
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4
分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Cheng, J, Berninghausen, O, Beckmann, R.
登録日2021-05-11
公開日2021-09-15
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A distinct assembly pathway of the human 39S late pre-mitoribosome.
Nat Commun, 12, 2021
7OF3
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BU of 7of3 by Molmil
Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset2).
分子名称: 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ...
著者Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R.
登録日2021-05-04
公開日2021-05-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
7BED
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BU of 7bed by Molmil
X-ray structure of WDR5 bound to the WDR5 win motif peptide
分子名称: SULFATE ION, WD repeat-containing protein 5
著者McVey, C.E, Kaye, K.M.
登録日2020-12-23
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献MLL1 is regulated by KSHV LANA and is important for virus latency.
Nucleic Acids Res., 49, 2021
7BCY
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BU of 7bcy by Molmil
X-ray structure of WDR5delta24 bound to the Kaposi's sarcoma herpesvirus LANA win motif peptide
分子名称: ORF 73, WD repeat-containing protein 5
著者McVey, C.E, Kaye, K.M.
登録日2020-12-21
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献MLL1 is regulated by KSHV LANA and is important for virus latency.
Nucleic Acids Res., 49, 2021
5GOW
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BU of 5gow by Molmil
Solution structure of the complex between DP1 acidic region and TFIIH p62 PH domain
分子名称: DP1, General transcription factor IIH subunit 1
著者Okuda, M, Nishimura, Y.
登録日2016-07-29
公開日2016-12-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH
J. Mol. Biol., 428, 2016
8IPP
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BU of 8ipp by Molmil
Crystal structure of the complex between an ankyrin and a parallel G-quadruplex
分子名称: 93del-T12, DARPin protein 2E4, MAGNESIUM ION, ...
著者Ngo, K.H, Liew, C.W, Heddi, B, Phan, A.T.
登録日2023-03-14
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Structural Basis for Parallel G-Quadruplex Recognition by an Ankyrin Protein.
J.Am.Chem.Soc., 146, 2024
3ZVM
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BU of 3zvm by Molmil
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*GP*TP*CP*AP*CP)-3', ACETATE ION, ...
著者Garces, F, Pearl, L.H, Oliver, A.W.
登録日2011-07-25
公開日2011-11-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol. Cell, 44, 2011
3T22
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BU of 3t22 by Molmil
Crystal structure of OxyR mutant from Porphyromonas gingivalis
分子名称: Redox-sensitive transcriptional activator OxyR
著者Svintradze, D.V, Wright, H.T, Lewis, J.P.
登録日2011-07-22
公開日2013-04-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the Porphyromonas gingivalis OxyR regulatory domain explain differences in expression of the OxyR regulon in Escherichia coli and P. gingivalis.
Acta Crystallogr.,Sect.D, 69, 2013
6UGL
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BU of 6ugl by Molmil
VqmA bound to DPO
分子名称: 3,5-dimethylpyrazin-2(1H)-one, Helix-turn-helix transcriptional regulator
著者Paczkowski, J.E, Huang, X.
登録日2019-09-26
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Mechanism underlying autoinducer recognition in theVibrio choleraeDPO-VqmA quorum-sensing pathway.
J.Biol.Chem., 295, 2020

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