3MNN
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![BU of 3mnn by Molmil](/molmil-images/mine/3mnn) | A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core | 分子名称: | 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ... | 著者 | Ong, M.S, Davey, C.A. | 登録日 | 2010-04-22 | 公開日 | 2011-04-06 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core Chemistry, 17, 2011
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1DLO
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![BU of 1dlo by Molmil](/molmil-images/mine/1dlo) | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | 分子名称: | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE | 著者 | Hsiou, Y, Ding, J, Das, K, Hughes, S, Arnold, E. | 登録日 | 1996-04-17 | 公開日 | 1996-08-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms. Structure, 4, 1996
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8UH4
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![BU of 8uh4 by Molmil](/molmil-images/mine/8uh4) | |
8UGQ
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3DB4
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![BU of 3db4 by Molmil](/molmil-images/mine/3db4) | Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 | 分子名称: | E3 ubiquitin-protein ligase UHRF1, SULFATE ION | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-05-30 | 公開日 | 2008-09-16 | 最終更新日 | 2012-04-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J.Biol.Chem., 286, 2011
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6JQ4
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![BU of 6jq4 by Molmil](/molmil-images/mine/6jq4) | HIGA Escherichia coli-K12 | 分子名称: | Antitoxin HigA | 著者 | She, Z, Xu, B.S. | 登録日 | 2019-03-28 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Conformational changes of antitoxin HigA from Escherichia coli str. K-12 upon binding of its cognate toxin HigB reveal a new regulation mechanism in toxin-antitoxin systems. Biochem.Biophys.Res.Commun., 514, 2019
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3F8T
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1ASU
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![BU of 1asu by Molmil](/molmil-images/mine/1asu) | AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AVIAN SARCOMA VIRUS INTEGRASE | 著者 | Bujacz, G, Jaskolski, M, Alexandratos, J, Wlodawer, A. | 登録日 | 1995-08-25 | 公開日 | 1995-11-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High-resolution structure of the catalytic domain of avian sarcoma virus integrase. J.Mol.Biol., 253, 1995
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8QSJ
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![BU of 8qsj by Molmil](/molmil-images/mine/8qsj) | Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Ritter, C, Nguyen, T.G, Kummer, E. | 登録日 | 2023-10-10 | 公開日 | 2023-12-13 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome. Nat Commun, 14, 2023
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8GLV
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4DAY
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8DEY
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![BU of 8dey by Molmil](/molmil-images/mine/8dey) | Ternary complex structure of Cereblon-DDB1 bound to IKZF2(ZF2,3) and the molecular glue DKY709 | 分子名称: | (3S)-3-[5-(1-benzylpiperidin-4-yl)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | 著者 | Ma, X, Ornelas, E, Clifton, M.C. | 登録日 | 2022-06-21 | 公開日 | 2023-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy. Cell Chem Biol, 30, 2023
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3ZVN
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![BU of 3zvn by Molmil](/molmil-images/mine/3zvn) | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase | 分子名称: | 5'-D(*GP*TP*CP*AP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, ... | 著者 | Garces, F, Pearl, L.H, Oliver, A.W. | 登録日 | 2011-07-25 | 公開日 | 2011-11-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase. Mol. Cell, 44, 2011
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7OF7
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![BU of 7of7 by Molmil](/molmil-images/mine/7of7) | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 and GTPBP5 (dataset1). | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | 登録日 | 2021-05-04 | 公開日 | 2021-06-23 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nat Commun, 12, 2021
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7ODT
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![BU of 7odt by Molmil](/molmil-images/mine/7odt) | State C of the human mitoribosomal large subunit assembly intermediate | 分子名称: | 16S mitochondrial rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N. | 登録日 | 2021-04-30 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Stepwise maturation of the peptidyl transferase region of human mitoribosomes. Nat Commun, 12, 2021
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8OO4
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7OIC
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![BU of 7oic by Molmil](/molmil-images/mine/7oic) | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2021-05-11 | 公開日 | 2021-09-15 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A distinct assembly pathway of the human 39S late pre-mitoribosome. Nat Commun, 12, 2021
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7OF3
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![BU of 7of3 by Molmil](/molmil-images/mine/7of3) | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset2). | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | 登録日 | 2021-05-04 | 公開日 | 2021-05-19 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nat Commun, 12, 2021
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7BED
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7BCY
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5GOW
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8IPP
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![BU of 8ipp by Molmil](/molmil-images/mine/8ipp) | Crystal structure of the complex between an ankyrin and a parallel G-quadruplex | 分子名称: | 93del-T12, DARPin protein 2E4, MAGNESIUM ION, ... | 著者 | Ngo, K.H, Liew, C.W, Heddi, B, Phan, A.T. | 登録日 | 2023-03-14 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.007 Å) | 主引用文献 | Structural Basis for Parallel G-Quadruplex Recognition by an Ankyrin Protein. J.Am.Chem.Soc., 146, 2024
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3ZVM
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![BU of 3zvm by Molmil](/molmil-images/mine/3zvm) | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*GP*TP*CP*AP*CP)-3', ACETATE ION, ... | 著者 | Garces, F, Pearl, L.H, Oliver, A.W. | 登録日 | 2011-07-25 | 公開日 | 2011-11-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase. Mol. Cell, 44, 2011
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3T22
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6UGL
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![BU of 6ugl by Molmil](/molmil-images/mine/6ugl) | VqmA bound to DPO | 分子名称: | 3,5-dimethylpyrazin-2(1H)-one, Helix-turn-helix transcriptional regulator | 著者 | Paczkowski, J.E, Huang, X. | 登録日 | 2019-09-26 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Mechanism underlying autoinducer recognition in theVibrio choleraeDPO-VqmA quorum-sensing pathway. J.Biol.Chem., 295, 2020
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