PDB: 7742 件ウェブページステータス検索Chemie searchBIRD

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7FAG	Room temperature structure of elastase with high-strength agarose hydrogel 分子名称: CALCIUM ION, Chymotrypsin-like elastase family member 1, SULFATE ION, ... 著者 Sugiyama, S, Kakinouchi, K, Adachi, H, Murata, M, Mori, Y. 登録日 2021-07-06 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Room temperature structure of elastase with high-strength agarose hydrogel To Be Published
3FVA	NNQNTF segment from elk prion 分子名称: Major prion protein 著者 Apostol, M.I, Eisenberg, D. 登録日 2009-01-15 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.458 Å) 主引用文献 Molecular mechanisms for protein-encoded inheritance. Nat.Struct.Mol.Biol., 16, 2009
1ELV	CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE 分子名称: 2-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1S COMPONENT, ... 著者 Gaboriaud, C, Rossi, V, Bally, I, Arlaud, G, Fontecilla-Camps, J.-C. 登録日 2000-03-14 公開日 2001-03-14 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle. EMBO J., 19, 2000
3BWM	Crystal Structure of Human Catechol O-Methyltransferase with bound SAM and DNC 分子名称: 3,5-DINITROCATECHOL, Catechol O-methyltransferase, MAGNESIUM ION, ... 著者 Rutherford, K, Le Trong, I, Stenkamp, R.E, Parson, W.W. 登録日 2008-01-09 公開日 2008-06-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structures of human 108V and 108M catechol O-methyltransferase. J.Mol.Biol., 380, 2008
3CLN	STRUCTURE OF CALMODULIN REFINED AT 2.2 ANGSTROMS RESOLUTION 分子名称: CALCIUM ION, CALMODULIN 著者 Babu, Y.S, Bugg, C.E, Cook, W.J. 登録日 1988-05-11 公開日 1988-07-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of calmodulin refined at 2.2 A resolution. J.Mol.Biol., 204, 1988
3FR1	NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin) 分子名称: CHLORIDE ION, Islet amyloid polypeptide 著者 Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. 登録日 2009-01-08 公開日 2009-06-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular mechanisms for protein-encoded inheritance Nat.Struct.Mol.Biol., 16, 2009
8TLY	Human ASCC1 Phosphodiesterase/Ligase Domain 分子名称: Activating signal cointegrator 1 complex subunit 1 著者 Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Thapar, R. 登録日 2023-07-27 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase. J.Biol.Chem., 300, 2024
8TUK	Alvinella ASCC1 KH and Phosphodiesterase/Ligase Domain 分子名称: 1,2-ETHANEDIOL, Activating signal cointegrator 1 complex subunit 1, IMIDAZOLE 著者 Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Chinnam, N.B. 登録日 2023-08-16 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase. J.Biol.Chem., 300, 2024
1SI5	Protease-like domain from 2-chain hepatocyte growth factor 分子名称: hepatocyte growth factor 著者 Kirchhofer, D, Yao, X, Peek, M, Eigenbrot, C, Lipari, M.T, Billeci, K.L, Maun, H.R, Moran, P, Santell, L, Lazarus, R.A. 登録日 2004-02-27 公開日 2004-12-28 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling J.Biol.Chem., 279, 2004
5SGA	Structures of product and inhibitor complexes of Streptomyces griseus protease a at 1.8 Angstroms resolution. a model for serine protease catalysis 分子名称: PROTEINASE A (SGPA), TETRAPEPTIDE ACE-PRO-ALA-PRO-TYR 著者 Sielecki, A.R, James, M.N.G. 登録日 1990-05-29 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis. J.Mol.Biol., 144, 1980
8A7P	beta-2-microglobulin DeltaN6 amyloid fibril form 2PFb 分子名称: Beta-2-microglobulin form pI 5.3 著者 Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A. 登録日 2022-06-21 公開日 2023-03-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Disease-relevant beta 2 -microglobulin variants share a common amyloid fold. Nat Commun, 14, 2023
4K1T	Gly-Ser-SplB protease from Staphylococcus aureus at 1.60 A resolution 分子名称: CHLORIDE ION, SULFATE ION, Serine protease SplB, ... 著者 Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. 登録日 2013-04-05 公開日 2014-04-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation. J.Biol.Chem., 289, 2014
4K1S	Gly-Ser-SplB protease from Staphylococcus aureus at 1.96 A resolution 分子名称: Serine protease SplB 著者 Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. 登録日 2013-04-05 公開日 2014-04-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation. J.Biol.Chem., 289, 2014
1HLT	THE STRUCTURE OF A NONADECAPEPTIDE OF THE FIFTH EGF DOMAIN OF THROMBOMODULIN COMPLEXED WITH THROMBIN 分子名称: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... 著者 Tulinsky, A, Mathews, I.I. 登録日 1994-08-28 公開日 1994-12-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin. Biochemistry, 33, 1994
6EST	INTERACTION OF THE PEPTIDE CF3-LEU-ALA-NH-C6H4-CF3(TFLA) WITH PORCINE PANCREATIC ELASTASE. X-RAY STUDIES AT 1.8 ANGSTROMS 分子名称: CALCIUM ION, DIMETHYLFORMAMIDE, PORCINE PANCREATIC ELASTASE, ... 著者 Prange, T, Li De Lasierra, I. 登録日 1990-06-15 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A. J.Mol.Recog., 3, 1990
6TNA	CRYSTAL STRUCTURE OF YEAST PHENYLALANINE T-RNA. I.CRYSTALLOGRAPHIC REFINEMENT 分子名称: MAGNESIUM ION, TRNAPHE 著者 Sussman, J.L, Holbrook, S.R, Warrant, R.W, Church, G.M, Kim, S.-H. 登録日 1978-11-16 公開日 1979-01-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. J.Mol.Biol., 123, 1978
6TH7	Structure of porcine pancreatic elastase in complex with tutuilamide 分子名称: CALCIUM ION, Chymotrypsin-like elastase family member 1, Tutuilamide 著者 Koehnke, J, Sikandar, A. 登録日 2019-11-18 公開日 2020-03-04 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. Acs Chem.Biol., 15, 2020
8FNJ	Structure of E138K/G140A HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNN	Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FND	Structure of E138K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNO	Structure of E138K/G140A/Q148R HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-28 公開日 2023-08-09 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FN7	Structure of WT HIV-1 intasome bound to Dolutegravir 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNH	Structure of Q148K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNL	Structure of E138K/Q148K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8FNP	Structure of E138K/G140S/Q148H HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-28 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023

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