6YE1
| Human Ecto-5'-nucleotidase (CD73) in complex with the AMPCP derivative A894 (compound 2n in publication) in the closed form (crystal form IV) | 分子名称: | 5'-nucleotidase, ZINC ION, [(2~{R},3~{S},4~{R},5~{R})-5-[2-chloranyl-6-(cyclopentylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxymethylphosphonic acid | 著者 | Scaletti, E, Strater, N. | 登録日 | 2020-03-23 | 公開日 | 2021-01-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors. J.Med.Chem., 64, 2021
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8OI2
| Crystal structure of Alb1 megabody in complex with human serum albumin | 分子名称: | Alb1 Megabody, Albumin | 著者 | De Felice, S, Zoia, G, Romanyuk, Z, Pardon, E, Steyaert, J, Angelini, A, Cendron, L. | 登録日 | 2023-03-22 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of human serum albumin in complex with megabody reveals unique human and murine cross-reactive binding site. Protein Sci., 33, 2024
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6YEJ
| Cryo-EM structure of the Full-length disease type human Huntingtin | 分子名称: | Huntingtin | 著者 | Tame, G, Jung, T, Dal Perraro, M, Hebert, H, Song, J. | 登録日 | 2020-03-24 | 公開日 | 2020-12-16 | 実験手法 | ELECTRON MICROSCOPY (18.200001 Å) | 主引用文献 | The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain. Structure, 28, 2020
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4X2L
| Crystal structure of human BACE-1 bound to Compound 6 | 分子名称: | (4S)-4-(2,4-difluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... | 著者 | Vajdos, F.F, Parris, K. | 登録日 | 2014-11-26 | 公開日 | 2015-03-04 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design. J.Med.Chem., 58, 2015
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6Y9X
| Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,7) | 分子名称: | Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A | 著者 | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | 登録日 | 2020-03-10 | 公開日 | 2020-08-19 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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4LUH
| Complex of ovine serum albumin with 3,5-diiodosalicylic acid | 分子名称: | (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol, (2S)-2-hydroxybutanedioic acid, 2-HYDROXY-3,5-DIIODO-BENZOIC ACID, ... | 著者 | Bujacz, A, Talaj, J.A, Pietrzyk, A.J, Bujacz, G. | 登録日 | 2013-07-25 | 公開日 | 2014-09-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of ovine serum albumin and its complex with 3,5-diiodosalicylic acid To be Published
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5YVF
| Crystal structure of BFA1 | 分子名称: | BFA1 | 著者 | Pu, H, Zhang, L, Duan, Z.K, Peng, L.W, Liu, L. | 登録日 | 2017-11-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1. Plant Cell, 30, 2018
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6YJX
| Structure of Hen egg-white lysozyme crystallized with PAS polypeptide | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Schiefner, A, Skerra, A. | 登録日 | 2020-04-05 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Proline/alanine-rich sequence (PAS) polypeptides as an alternative to PEG precipitants for protein crystallization. Acta Crystallogr.,Sect.F, 76, 2020
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6YJY
| Crystal structure of human glutaminyl cyclase in complex with neurotensin 1-5 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTAMINE, Glutaminyl-peptide cyclotransferase, ... | 著者 | Funk, L.M, Sautner, V, Tittmann, K. | 登録日 | 2020-04-05 | 公開日 | 2020-07-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. Biochemistry, 59, 2020
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8GF3
| Crystallographic structure from BlMan5_7 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GH5 Mannanase, ... | 著者 | Briganti, L, Araujo, E.A, Polikarpov, I. | 登録日 | 2023-03-07 | 公開日 | 2024-04-17 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies. Int.J.Biol.Macromol., 274, 2024
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4X67
| Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions. | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Wang, L, Chong, J, Wang, D. | 登録日 | 2014-12-07 | 公開日 | 2015-02-04 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions. Proc.Natl.Acad.Sci.USA, 112, 2015
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5N6N
| CRYSTAL STRUCTURE OF THE 14-3-3:NEUTRAL TREHALASE NTH1 COMPLEX | 分子名称: | CALCIUM ION, Neutral trehalase, Protein BMH1, ... | 著者 | Alblova, M, Smidova, A, Obsilova, V, Obsil, T. | 登録日 | 2017-02-15 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1GT0
| Crystal structure of a POU/HMG/DNA ternary complex | 分子名称: | 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ... | 著者 | Remenyi, A, Wilmanns, M. | 登録日 | 2002-01-09 | 公開日 | 2003-01-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers Genes Dev., 17, 2003
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5DBK
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5YXE
| Crystal Structure Analysis of feline serum albumin | 分子名称: | Serum albumin | 著者 | Kihira, K, Yokomaku, K, Akiyama, M, Morita, Y, Komatsu, T. | 登録日 | 2017-12-05 | 公開日 | 2018-04-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.40241528 Å) | 主引用文献 | Core-shell protein cluster comprising haemoglobin and recombinant feline serum albumin as an artificial O2 carrier for cats J Mater Chem B., 2018
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4L9Q
| X-ray study of human serum albumin complexed with teniposide | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, SERUM ALBUMIN | 著者 | Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. | 登録日 | 2013-06-18 | 公開日 | 2013-07-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830, 2013
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6Y57
| Structure of human ribosome in hybrid-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-25 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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1H0J
| Structural Basis of the Membrane-induced Cardiotoxin A3 Oligomerization | 分子名称: | CARDIOTOXIN-3, DODECYL SULFATE | 著者 | Forouhar, F, Huang, W.-N, Liu, J.-H, Chien, K.-Y, Wu, W.-G, Hsiao, C.-D. | 登録日 | 2002-06-20 | 公開日 | 2003-06-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis of Membrane-Induced Cardiotoxin A3 Oligomerization J.Biol.Chem., 278, 2003
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4X1X
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5D9T
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1H3H
| Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain | 分子名称: | GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 | 著者 | Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S. | 登録日 | 2002-09-03 | 公開日 | 2003-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition Mol.Cell, 11, 2003
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8GMW
| Crystal structure of lysozyme | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Nam, K.H. | 登録日 | 2022-08-22 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of lysozyme To Be Published
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6YDU
| XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, reoxidized diferric state, 10s O2 exposure. | 分子名称: | FE (III) ION, GLYCEROL, Methane monooxygenase, ... | 著者 | Srinivas, V, Hogbom, M. | 登録日 | 2020-03-21 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
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5D9X
| Dehydroascorbate reductase complexed with GSH | 分子名称: | CALCIUM ION, Dehydroascorbate reductase, GLUTATHIONE | 著者 | Do, H, Lee, J.H. | 登録日 | 2015-08-19 | 公開日 | 2016-02-03 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L. japonica Sci Rep, 6, 2016
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8GMV
| Crystal structure of lysozyme | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Nam, K.H. | 登録日 | 2022-08-22 | 公開日 | 2022-09-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of lysozyme To Be Published
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