PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6B7K	GH43 Endo-Arabinanase from Bacillus licheniformis 分子名称: CALCIUM ION, Endo-alpha-(1->5)-L-arabinanase 著者 Farro, E.G.S, Nascimento, A.S. 登録日 2017-10-04 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 GH43 endo-arabinanase from Bacillus licheniformis: Structure, activity and unexpected synergistic effect on cellulose enzymatic hydrolysis. Int. J. Biol. Macromol., 117, 2018
6G2S	Crystal structure of FimH in complex with a pentaflourinated biphenyl alpha D-mannoside 分子名称: (2~{R},3~{S},4~{S},5~{S},6~{R})-2-(hydroxymethyl)-6-[4-[2,3,4,5,6-pentakis(fluoranyl)phenyl]phenoxy]oxane-3,4,5-triol, SULFATE ION, Type 1 fimbrin D-mannose specific adhesin 著者 Jakob, R.P, Schoenemann, W, Cramer, J, Muehlethaler, T, Daetwyler, P, Zihlmann, P, Fiege, B, Sager, C.P, Smiesko, M, Rabbani, S, Eris, D, Schwardt, O, Maier, T, Ernst, B. 登録日 2018-03-23 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists. Chemmedchem, 14, 2019
6G99	Solution structure of FUS-ZnF bound to UGGUG 分子名称: RNA (5'-R(*UP*GP*GP*UP*G)-3'), RNA-binding protein FUS, ZINC ION 著者 Loughlin, F.E, Allain, F.H.-T. 登録日 2018-04-10 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
6BED	Crystal structure of VACV D13 in complex with Rifampicin 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, RIFAMPICIN, ... 著者 Garriga, D, Accurso, C, Coulibaly, F. 登録日 2017-10-25 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GC5	Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM 分子名称: AU-rich RNA, ELAV-like protein 1 著者 Ripin, N, Allain, F.H. 登録日 2018-04-17 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6G2R	Crystal structure of FimH in complex with a tetraflourinated biphenyl alpha D-mannoside 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[3-chloranyl-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-phenyl]-2,3,5,6-tetrakis(fluoranyl)benzenecarbonitrile, SULFATE ION, ... 著者 Jakob, R.P, Schoenemann, W, Cramer, J, Muehlethaler, T, Daetwyler, P, Zihlmann, P, Fiege, B, Sager, C.P, Smiesko, M, Rabbani, S, Eris, D, Schwardt, O, Maier, T, Ernst, B. 登録日 2018-03-23 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists. Chemmedchem, 14, 2019
6DN7	SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor 分子名称: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor 著者 Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. 登録日 2018-06-06 公開日 2019-04-17 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
6GN1	Crystal Structure of Glycogen synthase kinase-3 beta (GSK3B) in Complex with PIK-75 分子名称: CHLORIDE ION, Glycogen synthase kinase-3 beta, ~{N}-[(~{E})-(6-bromanylimidazo[1,2-a]pyridin-3-yl)methylideneamino]-~{N},2-dimethyl-5-nitro-benzenesulfonamide 著者 Tesch, R, Becker, C, Mueller, M.P, Sant'Anna, C.M.R, Fraga, C.A.M, Rauh, D. 登録日 2018-05-29 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 An Unusual Intramolecular Halogen Bond Guides Conformational Selection. Angew. Chem. Int. Ed. Engl., 57, 2018
6DAF	2.4 Angstrom crystal structure of the F141L Ca/CaM:CaV1.2 IQ domain complex 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Wang, K, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1X	Crystal Structure of Ketosteroid Isomerase D40N/D103N mutant from Pseudomonas Putida (pKSI) bound to 3,4-dinitrophenol 分子名称: 3,4-dinitrophenol, MAGNESIUM ION, Steroid Delta-isomerase 著者 Yabukarski, F, Pinney, M.M, Herschlag, D. 登録日 2018-01-05 公開日 2018-07-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Structural Coupling Throughout the Active Site Hydrogen Bond Networks of Ketosteroid Isomerase and Photoactive Yellow Protein. J. Am. Chem. Soc., 140, 2018
6ER3	Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,3 sialyllactose 分子名称: BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose 著者 Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. 登録日 2017-10-16 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
6ES7	Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins 分子名称: CREB-binding protein, Nuclear receptor coactivator 3 著者 Chi, N.C. 登録日 2017-10-19 公開日 2018-10-31 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins. Sci Adv, 4, 2018
6E94	Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA 分子名称: DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... 著者 Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. 登録日 2018-07-31 公開日 2018-11-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.594 Å) 主引用文献 Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
6E5I	Heterogeneous-Backbone Mimics of a Designed Disulfide-Rich Protein: Orn turn 分子名称: Designed peptide NC_HEE_D1: Orn turn mutant 著者 Cabalteja, C.C, Mihalko, D.S, Horne, W.S. 登録日 2018-07-20 公開日 2018-11-21 最終更新日 2020-01-01 実験手法 SOLUTION NMR 主引用文献 Heterogeneous-Backbone Foldamer Mimics of a Computationally Designed, Disulfide-Rich Miniprotein. Chembiochem, 20, 2019
6BQS	HusA haemophore from Porphyromonas gingivalis 分子名称: hypothetical protein PG_2227 著者 Gell, D.A, Kwan, A.H, Horne, J, Hugrass, B.M, Collins, D.A.T. 登録日 2017-11-28 公開日 2018-10-10 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis. Nat Commun, 9, 2018
6BSB	Crystal structure of the Mucin-1 SEA domain, L1105M mutant, Selenium-derivative 分子名称: Mucin-1 著者 Noguera, M.E, Jakoncic, J, Ermacora, M.R. 登録日 2017-12-01 公開日 2018-12-05 最終更新日 2020-06-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain. Biochim Biophys Acta Proteins Proteom, 1868, 2020
6BTA	CypA Mutant - S99T C115S 分子名称: Peptidyl-prolyl cis-trans isomerase A 著者 Fraser, J.S, Kenner, L.R, Liu, L. 登録日 2017-12-06 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Rescue of conformational dynamics in enzyme catalysis by directed evolution. Nat Commun, 9, 2018
6EGZ	Crystal structure of cytochrome c in complex with di-PEGylated sulfonatocalix[4]arene 分子名称: Cytochrome c iso-1, HEME C, SODIUM ION, ... 著者 Mummidivarapu, V.V.S, Rennie, M.L, Crowley, P.B. 登録日 2017-09-12 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Noncovalent PEGylation via Sulfonatocalix[4]arene-A Crystallographic Proof. Bioconjug.Chem., 29, 2018
6GZN	Adenine-driven structural switch from two- to three-quartet DNA G-quadruplex 分子名称: DNA (5'-D(*GP*GP*GP*TP*AP*GP*GP*GP*AP*GP*CP*GP*GP*GP*AP*GP*AP*GP*GP*G)-3') 著者 Lenarcic Zivkovic, M, Rozman, J, Plavec, J. 登録日 2018-07-04 公開日 2018-09-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Adenine-Driven Structural Switch from a Two- to Three-Quartet DNA G-Quadruplex. Angew. Chem. Int. Ed. Engl., 57, 2018
6H7B	Structure of Leishmania PABP1 (domain J) complexed with a peptide containing the PAM2 motif of eIF4E4. 分子名称: HIS-HIS-MET-ASN-PRO-ASN-ALA-THR-GLU-PHE-MET-PRO, Polyadenylate-binding protein 著者 Cameron, A.D, Firczuk, H, dos Santos Rodrigues, F.H, McCarthy, J.E.G. 登録日 2018-07-31 公開日 2018-12-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs. Nucleic Acids Res., 47, 2019
6DKF	Caseinolytic protease (ClpP) from Staphylococcus aureus mutant - V7A 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Ripstein, Z.A, Vahidi, S, Kay, L.E, Rubinstein, J.L. 登録日 2018-05-29 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Reversible inhibition of the ClpP protease via an N-terminal conformational switch. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DMS	Endo-fucoidan hydrolase MfFcnA4_H294Q from glycoside hydrolase family 107 分子名称: 1,2-ETHANEDIOL, Alpha-1,4-endofucoidanase, CALCIUM ION 著者 Vickers, C, Abe, K, Salama-Alber, O, Boraston, A.B. 登録日 2018-06-05 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to alpha-l-fucosidases from GH29. J. Biol. Chem., 293, 2018
6DGO	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Troglitazone 分子名称: (5S)-5-[(4-{[(2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl]methoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma 著者 Shang, J, Kojetin, D.J. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
6DAE	2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Wang, K, Lu, J, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DL1	Racemic structure of jatrophidin, an orbitide from Jatropha curcas 分子名称: jatrophidin 著者 Wang, C.K, King, G.J, Ramalho, S.D. 登録日 2018-05-31 公開日 2018-11-14 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.029 Å) 主引用文献 Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species. J. Nat. Prod., 81, 2018

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