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4JQU
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Crystal structure of Ubc7p in complex with the U7BR of Cue1p
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ...
著者Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X.
登録日2013-03-20
公開日2013-05-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms.
Mol.Cell, 50, 2013
1UIY
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Crystal Structure of Enoyl-CoA Hydratase from Thermus Thermophilus HB8
分子名称: 1,4-DIETHYLENE DIOXIDE, Enoyl-CoA Hydratase, GLYCEROL
著者Bagautdinov, B, Kuramitsu, S, Yokoyama, S, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-24
公開日2003-08-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of enoyl-CoA hydratase from Thermus thermophilus HB8.
Acta Crystallogr.,Sect.F, 77, 2021
8B6C
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BU of 8b6c by Molmil
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147
分子名称: 28S rRNA, 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazacyclododec-1-yl]sulfonyl]-~{N},~{N}-dimethyl-aniline, 5.8S rRNA, ...
著者Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
登録日2022-09-26
公開日2023-02-22
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
2N3B
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Structure of oxidized horse heart cytochrome c encapsulated in reverse micelles
分子名称: Cytochrome c, HEME C
著者O'Brien, E.S, Nucci, N.V, Fuglestad, B, Tommos, C, Wand, A.
登録日2015-05-27
公開日2015-10-28
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Defining the Apoptotic Trigger: THE INTERACTION OF CYTOCHROME c AND CARDIOLIPIN.
J.Biol.Chem., 290, 2015
8BRP
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BU of 8brp by Molmil
Peptide Arginase OspR from the cyanobacterium Kamptonema sp.
分子名称: ACETATE ION, GLYCEROL, MAGNESIUM ION, ...
著者Mordhorst, S, Badmann, T, Boesch, N.M, Morinaka, B.I, Rach, H, Piel, J, Groll, M, Vagstadt, A.L.
登録日2022-11-23
公開日2023-03-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Biochemical Insights into Post-Translational Arginine-to-Ornithine Peptide Modifications by an Atypical Arginase.
Acs Chem.Biol., 18, 2023
7LL8
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BU of 7ll8 by Molmil
D-Protein RFX-V1 Bound to the VEGFR1 Domain 2 Site on VEGF-A
分子名称: Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V1
著者Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S.
登録日2021-02-03
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth.
Acs Chem.Biol., 16, 2021
8B5L
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BU of 8b5l by Molmil
Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Pauwels, E, Shewakramani, N.R, De Wijngaert, B, Vermeire, K, Das, K.
登録日2022-09-23
公開日2023-03-01
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.
Sci Adv, 9, 2023
7LL9
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D-Protein RFX-V2 Bound to the VEGFR1 Domain 3 Site on VEGF-A
分子名称: Isoform L-VEGF189 of Vascular endothelial growth factor A, RFX-V2
著者Marinec, P.S, Landgraf, K.E, Uppalapati, M, Chen, G, Xie, D, Jiang, Q, Zhao, Y, Petriello, A, Deshayes, K, Kent, S.B.H, Ault-Riche, D, Sidhu, S.S.
登録日2021-02-03
公開日2021-03-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth.
Acs Chem.Biol., 16, 2021
3F8T
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BU of 3f8t by Molmil
Crystal structure analysis of a full-length MCM homolog from Methanopyrus kandleri
分子名称: Predicted ATPase involved in replication control, Cdc46/Mcm family
著者Bae, B, Nair, S.K.
登録日2008-11-13
公開日2009-03-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the Architecture of the Replicative Helicase from the Structure of an Archaeal MCM Homolog.
Structure, 17, 2009
4YXY
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BU of 4yxy by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats; two linked rings of 12 repeats each structure
分子名称: dTor_9x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
2NCD
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BU of 2ncd by Molmil
NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER
分子名称: ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION
著者Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J.
登録日1999-06-04
公開日1999-06-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Direction determination in the minus-end-directed kinesin motor ncd.
Nature, 395, 1998
8BCH
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BU of 8bch by Molmil
Human Brr2 Helicase Region in complex with Sulfaguanidine
分子名称: 1-(4-aminophenyl)sulfonylguanidine, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
6XNV
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BU of 6xnv by Molmil
CRYSTAL STRUCTURE OF LISTERIA MONOCYTOGENES CBPB PROTEIN (LMO1009) IN COMPLEX WITH C-DI-AMP
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, CBS domain-containing protein
著者Luo, S, Tong, L.
登録日2020-07-04
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes.
Mbio, 11, 2020
2MVX
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BU of 2mvx by Molmil
Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation
分子名称: Amyloid beta A4 protein
著者Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H.
登録日2014-10-17
公開日2014-11-26
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation.
Angew.Chem.Int.Ed.Engl., 54, 2015
1UJZ
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BU of 1ujz by Molmil
Crystal structure of the E7_C/Im7_C complex; a computationally designed interface between the colicin E7 DNase and the Im7 Immunity protein
分子名称: Designed Colicin E7 DNase, Designed Colicin E7 immunity protein
著者Kortemme, T, Joachimiak, L.A, Bullock, A.N, Schuler, A.D, Stoddard, B.L, Baker, D.
登録日2003-08-13
公開日2004-04-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Computational redesign of protein-protein interaction specificity
NAT.STRUCT.MOL.BIOL., 11, 2004
3FB7
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BU of 3fb7 by Molmil
Open KcsA potassium channel in the presence of Rb+ ion
分子名称: RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
著者Cuello, L.G, Jogini, V, Cortes, D.M, Pan, A.C, Gagnon, D.H, Cordero-Morales, J.F, Chakrapani, S, Roux, B, Perozo, E.
登録日2008-11-18
公開日2010-07-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Open KcsA potassium channel in the presence of Rb+ ion
TO BE PUBLISHED
2NND
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BU of 2nnd by Molmil
The Structural Identification of the Interaction Site and Functional State of RBP for its Membrane Receptor
分子名称: 2-ISOBUTYL-3-METHOXYPYRAZINE, CADMIUM ION, Major urinary protein 2
著者Redondo, C, Bingham, R.J, Vouropoulou, M, Homans, S.W, Findlay, J.B.
登録日2006-10-24
公開日2007-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Identification of the retinol-binding protein (RBP) interaction site and functional state of RBPs for the membrane receptor.
Faseb J., 22, 2008
4ZE2
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BU of 4ze2 by Molmil
Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140H mutant complexed with itraconazole
分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE
著者Sagatova, A, Keniya, M.V, Wilson, R, Monk, B.C, Tyndall, J.D.A.
登録日2015-04-20
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase.
Sci Rep, 6, 2016
4L9B
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BU of 4l9b by Molmil
Structure of native RBP from lactococcal phage 1358 (CsI derivative)
分子名称: CESIUM ION, Receptor Binding Protein
著者Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C.
登録日2013-06-18
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism
To be Published
8UK5
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Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac
分子名称: ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac
著者Montgomery, C, Phillips, M, Nix, J.C, Glass, K.C.
登録日2023-10-12
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
8OIG
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BU of 8oig by Molmil
Crystal Structure of Staphopain C from Staphylococcus aureus
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者McEwen, A.G, Magoch, M, Napolitano, V, Dubin, G, Wladyka, B.
登録日2023-03-22
公開日2023-06-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal Structure of Staphopain C from Staphylococcus aureus.
Molecules, 28, 2023
5NX0
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Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at room temperature
分子名称: Endolysin
著者Gohlke, U, Loll, B, Consentius, P, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T.
登録日2017-05-09
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.803 Å)
主引用文献Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals.
Phys Chem Chem Phys, 19, 2017
3FH8
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Leukotriene A4 Hydrolase complexed with inhibitor 1-[2-(4-benzylphenoxy)ethyl]pyrrolidine.
分子名称: 1-[2-(4-benzylphenoxy)ethyl]pyrrolidine, ACETATE ION, IMIDAZOLE, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-09
公開日2010-01-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
6X42
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High Resolution Crystal Structure Analysis of SERA5E from plasmodium falciparum
分子名称: 1,2-ETHANEDIOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CALCIUM ION, ...
著者Clarke, O.B, Smith, N.A, Lee, M, Smith, B.J.
登録日2020-05-21
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of the Plasmodium falciparum PfSERA5 pseudo-zymogen.
Protein Sci., 29, 2020
5OE2
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CRYSTAL STRUCTURE OF THE BETA-LACTAMASE OXA-245
分子名称: Beta-lactamase, CHLORIDE ION, SODIUM ION
著者Lund, B.A, Leiros, H.K.S.
登録日2017-07-07
公開日2017-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis.
Acta Crystallogr F Struct Biol Commun, 73, 2017

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