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7TBI
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Composite structure of the S. cerevisiae nuclear pore complex (NPC)
分子名称: Dyn2, Nic96 R1, Nic96 R2, ...
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-12-22
公開日2022-06-15
最終更新日2022-06-22
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7NYC
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cryoEM structure of 3C9-sMAC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Menny, A, Couves, E.C, Bubeck, D.
登録日2021-03-22
公開日2021-10-06
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
6Y8M
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Fragment bikinin bound to Interleukin 1 beta
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, Interleukin-1 beta, SULFATE ION
著者De Nicola, G.F, Nichols, C.E.
登録日2020-03-05
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment bikinin bound to Interleukin 1 beta
To Be Published
7O3H
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Murine CIII2 focus-refined from supercomplex CICIII2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Vercellino, I, Sazanov, L.A.
登録日2021-04-01
公開日2021-10-13
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.
Nature, 598, 2021
2I2X
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Crystal structure of methanol:cobalamin methyltransferase complex MtaBC from Methanosarcina barkeri
分子名称: 5-HYDROXYBENZIMIDAZOLYLCOB(III)AMIDE, Methyltransferase 1, POTASSIUM ION, ...
著者Hagemeier, C.H, Kruer, M, Thauer, R.K, Warkentin, E, Ermler, U.
登録日2006-08-17
公開日2006-11-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex
Proc.Natl.Acad.Sci.Usa, 103, 2006
7T9I
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Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein hormones alpha chain, ...
著者Faust, B, Cheng, Y, Manglik, A.
登録日2021-12-19
公開日2022-08-03
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Autoantibody mimicry of hormone action at the thyrotropin receptor.
Nature, 609, 2022
7SUE
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BU of 7sue by Molmil
Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2
分子名称: Nucleoprotein, S24-188 Fab Heavy chain, S24-188 Fab Light chain
著者Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-11-17
公開日2022-08-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
7OGQ
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Plant peptide hormone receptor H1I2S1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roman, A.O, Jimenez-Sandoval, P, Santiago, J.
登録日2021-05-07
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.
Nat Commun, 13, 2022
6YFG
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Virus-like particle of Beihai levi-like virus 32
分子名称: CALCIUM ION, coat protein
著者Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K.
登録日2020-03-26
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.897 Å)
主引用文献Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
6YE2
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Human Ecto-5'-nucleotidase (CD73) in complex with the AMPCP derivative A1202 (compound 4a in publication) in the closed form (crystal form IV)
分子名称: 5'-nucleotidase, CALCIUM ION, ZINC ION, ...
著者Scaletti, E, Strater, N.
登録日2020-03-23
公開日2021-01-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors.
J.Med.Chem., 64, 2021
7TEJ
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Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ...
著者Walsh Jr, R.M, Rawson, S, Schnell, H.M, Hanna, J.
登録日2022-01-05
公開日2022-08-10
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Yeast PI31 inhibits the proteasome by a direct multisite mechanism.
Nat.Struct.Mol.Biol., 29, 2022
7ODV
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Plant peptide hormone receptor complex H1LS1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
著者Roman, A.O, Jimenez-Sandoval, P, Santiago, J.
登録日2021-04-30
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.
Nat Commun, 13, 2022
6YFL
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Virus-like particle of bacteriophage ESE020
分子名称: coat protein
著者Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K.
登録日2020-03-26
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
7OGZ
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Plant peptide hormone receptor complex H1L3S1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide hormone IDL3, ...
著者Roman, A.O, Jimenez-Sandoval, P, Santiago, J.
登録日2021-05-07
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.
Nat Commun, 13, 2022
6YFT
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Virus-like particle of Wenzhou levi-like virus 1
分子名称: RNA, coat protein
著者Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K.
登録日2020-03-26
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
7OGO
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Plant peptide hormone receptor H1I1S1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roman, A.O, Jimenez-Sandoval, P, Santiago, J.
登録日2021-05-07
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.
Nat Commun, 13, 2022
7NRZ
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Crystal structure of malate dehydrogenase from Trypanosoma cruzi
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sonani, R.R, Kurpiewska, K, Lewinski, K, Dubin, G.
登録日2021-03-04
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct sequence and structural feature of trypanosoma malate dehydrogenase.
Biochem.Biophys.Res.Commun., 557, 2021
7TFI
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Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
登録日2022-01-06
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFH
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Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
登録日2022-01-06
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFJ
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Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
登録日2022-01-06
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
6YGA
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BU of 6yga by Molmil
Crystal structure of the apo NatC complex
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2020-11-18
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
6YCS
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Human Transcription Cofactor PC4 DNA-binding domain in complex with full phosphorothioate 5-10-5 2'-O-methyl DNA gapmer antisense oligonucleotide.
分子名称: DNA (5'-D(P*(OKQ))-D(P*(OKT))-R(P*(RFJ))-D(*(OKQ)P*(OKT)P*(AS)P*(GS)P*(OKN)P*(OKN)P*(PST)P*(OKN)P*(PST)P*(GS)P*(GS)P*(AS)P*(OKT)P*(OKT))-3'), PC4 protein, SODIUM ION, ...
著者Hyjek-Skladanowska, M, Vickers, T.A, Napiorkowska, A, Anderson, B, Tanowitz, M, Crooke, S.T, Liang, X, Seth, P.P, Nowotny, M.
登録日2020-03-19
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins.
J.Am.Chem.Soc., 142, 2020
2IWS
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Radicicol analogues bound to the ATP site of HSP90
分子名称: (5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82
著者Roe, S.M, Prodromou, C, Pearl, L.H.
登録日2006-07-04
公開日2006-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Inhibition of Hsp90 with Synthetic Macrolactones: Synthesis and Structural and Biological Evaluation of Ring and Conformational Analogs of Radicicol.
Chem.Biol., 13, 2006
6YGD
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Crystal structure of the NatC complex bound to Gag peptide and CoA
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ...
著者Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O.
登録日2020-03-27
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates.
Nat Commun, 11, 2020
2IS2
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Crystal structure of UvrD-DNA binary complex
分子名称: 33-MER, DNA helicase II, FORMIC ACID, ...
著者Yang, W, Lee, J.Y.
登録日2006-10-16
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006

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