PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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7ERB	Crystal structure of human Biliverdin IX-beta reductase B with Ataluren (PTC) 分子名称: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid, Flavin reductase (NADPH), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Griesinger, C, Lee, D, Ryu, K.S, Kim, M, Ha, J.H. 登録日 2021-05-06 公開日 2022-01-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IX beta Reductase B as a Novel Thrombocytopenia Therapeutic Target. J.Med.Chem., 65, 2022
6H1T	Structure of the BM3 heme domain in complex with clotrimazole 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, ... 著者 Jeffreys, L.N, Munro, A.W.M, Leys, D. 登録日 2018-07-12 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs. Sci Rep, 9, 2019
6H50	Crystal structure of human KDM5B in complex with compound 34a 分子名称: 1,2-ETHANEDIOL, 8-[4-(1-methylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... 著者 Le Bihan, Y.V, Velupillai, S, van Montfort, R.L.M. 登録日 2018-07-23 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur.J.Med.Chem., 177, 2019
6H4Z	Crystal structure of human KDM5B in complex with compound 16a 分子名称: 1,2-ETHANEDIOL, 8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... 著者 Le Bihan, Y.V, Velupillai, S, van Montfort, R.L.M. 登録日 2018-07-23 公開日 2019-06-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur.J.Med.Chem., 177, 2019
3ZTL	Crystal structure of decameric form of Peroxiredoxin I from Schistosoma mansoni 分子名称: THIOREDOXIN PEROXIDASE 著者 Saccoccia, F, Angelucci, F, Bellelli, A, Boumis, G, Brunori, M, Miele, A.E. 登録日 2011-07-11 公開日 2012-03-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Moonlighting by Different Stressors: Crystal Structure of the Chaperone Species of a 2-Cys Peroxiredoxin. Structure, 20, 2012
7ETJ	C5 portal vertex in the partially-enveloped virion capsid 分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... 著者 Li, Z, Yu, X. 登録日 2021-05-13 公開日 2021-07-14 最終更新日 2021-08-18 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis for genome packaging, retention, and ejection in human cytomegalovirus. Nat Commun, 12, 2021
7ETO	C1 CVSC-binding penton vertex in the virion capsid of Human Cytomegalovirus 分子名称: Capsid vertex component 1, Capsid vertex component 2, Large tegument protein deneddylase, ... 著者 Li, Z, Yu, X. 登録日 2021-05-13 公開日 2021-07-14 最終更新日 2021-08-18 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural basis for genome packaging, retention, and ejection in human cytomegalovirus. Nat Commun, 12, 2021
4F74	Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of the substrate MA-CA. 分子名称: N terminal product of substrate MA-CA, Protease 著者 Schiffer, C.A, Mittal, S, Nalam, M.N.L. 登録日 2012-05-15 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of the substrate MA-CA. To be Published
7F3H	Crystal structure of cytochrome P450DA heme domain 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SERINE, ... 著者 Wan, N.W. 登録日 2021-06-16 公開日 2021-07-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Directed evolution of cytochrome P450DA hydroxylase activity for stereoselective biohydroxylation Catalysis Science And Technology, 12, 2022
4AEN	HLA-DR1 with covalently linked CLIP106-120 in reversed orientation 分子名称: GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... 著者 Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. 登録日 2012-01-11 公開日 2012-08-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex. J.Mol.Biol., 423, 2012
7EY7	bacteriophage T7 tail complex 分子名称: Internal virion protein gp14, Tail fiber protein, Tail tubular protein gp11, ... 著者 Liu, H.R, Chen, W.Y. 登録日 2021-05-30 公開日 2021-09-22 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural changes in bacteriophage T7 upon receptor-induced genome ejection. Proc.Natl.Acad.Sci.USA, 118, 2021
4F1E	The Crystal Structure of a Human MitoNEET mutant with Asp 67 replaced by a Gly 分子名称: CDGSH iron-sulfur domain-containing protein 1, FE2/S2 (INORGANIC) CLUSTER 著者 Baxter, E.I, Zuris, J.A, Wang, C, Axelrod, H.L, Cohen, A.E, Paddock, M.L, Nechushtai, R, Onuchic, J.N, Jennings, P.A. 登録日 2012-05-06 公開日 2012-12-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Allosteric control in a metalloprotein dramatically alters function. Proc.Natl.Acad.Sci.USA, 110, 2013
4AED	Crystal structure of Human enterovirus 71 分子名称: CALCIUM ION, LAURIC ACID, VP1, ... 著者 Plevka, P, Perera, R, Kuhn, R.J, Rossmann, M.G. 登録日 2012-01-09 公開日 2012-04-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Crystal Structure of Human Enterovirus 71. Science, 336, 2012
4F73	Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of CA-p2 cleavage site 分子名称: ACETATE ION, GLYCEROL, N terminal product of substrate CA-p2, ... 著者 Schiffer, C.A, Mittal, S, Nalam, M.N.L. 登録日 2012-05-15 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of active HIV-1 Protease in Complex with the N terminal product of CA-p2 cleavage site To be Published
3VCZ	1.80 Angstrom resolution crystal structure of a putative translation initiation inhibitor from Vibrio vulnificus CMCP6 分子名称: CALCIUM ION, Endoribonuclease L-PSP, GLYCEROL, ... 著者 Halavaty, A.S, Minasov, G, Filippova, E.V, Dubrovska, I, Winsor, J, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-01-04 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.80 Angstrom resolution crystal structure of a putative translation initiation inhibitor from Vibrio vulnificus CMCP6 To be Published
3VCD	Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32 分子名称: CHLORIDE ION, Propanediol utilization polyhedral body protein PduT, SULFATE ION 著者 Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O. 登録日 2012-01-03 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science, 336, 2012
3VJ6	Structure of the MHC class Ib molecule Qa-1b 分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-37 alpha chain, ... 著者 Zeng, L, Clements, C.S, Rossjohn, J. 登録日 2011-10-12 公開日 2012-03-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A structural basis for antigen presentation by the MHC class Ib molecule, Qa-1b J.Immunol., 188, 2012
7JG8	Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model) 分子名称: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... 著者 Guo, H, Courbon, G.M, Rubinstein, J.L. 登録日 2020-07-18 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589, 2021
7ICK	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF MGCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7ICG	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CDCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7ICQ	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996
7JGA	Cryo-EM structure of bedaquiline-saturated Mycobacterium smegmatis ATP synthase rotational state 3 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Guo, H, Courbon, G.M, Rubinstein, J.L. 登録日 2020-07-18 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589, 2021
7JK4	Structure of Drosophila ORC bound to AT-rich DNA and Cdc6 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (34-MER), ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-27 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7JGS	Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 2) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ... 著者 Schmidt, J.M, Bleichert, F. 登録日 2020-07-19 公開日 2020-09-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6. Nat Commun, 11, 2020
7ICS	DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 分子名称: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ... 著者 Pelletier, H, Sawaya, M.R. 登録日 1996-04-19 公開日 1996-04-19 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta Biochemistry, 35, 1996

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