PDB: 37084 件ウェブページステータス検索Chemie searchBIRD

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3FKZ	X-ray structure of the non covalent swapped form of the S16G/T17N/A19P/A20S/K31C/S32C mutant of bovine pancreatic ribonuclease 分子名称: Ribonuclease pancreatic 著者 Merlino, A, Russo Krauss, I, Perillo, M, Mattia, C.A, Ercole, C, Picone, D, Vergara, A, Sica, F. 登録日 2008-12-18 公開日 2009-03-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants Biopolymers, 91, 2009
4JVA	Crystal Structure of RIIbeta(108-402) bound to HE33, a N6 di-propyl substituted cAMP analog 分子名称: (2R,4aR,6R,7R,7aS)-6-[6-(dipropylamino)-9H-purin-9-yl]tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide, cAMP-dependent protein kinase type II-beta regulatory subunit 著者 Brown, S.H.J, Cheng, C.Y, Saldanha, A.S, Wu, J, Cottam, H, Sankaran, B, Taylor, S.S. 登録日 2013-03-25 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. Acs Chem.Biol., 8, 2013
3WRH	Crystal structure of P450cam 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H. 登録日 2014-02-25 公開日 2015-03-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structure of P450cam intermedite To be Published
3WPJ	SPATIOTEMPORAL DEVELOPMENT of SOAKED PROTEIN CRYSTAL; NATIVE 分子名称: Lysozyme C 著者 Mizutani, R, Saiga, R. 登録日 2014-01-12 公開日 2014-07-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Spatiotemporal development of soaked protein crystal Sci Rep, 4, 2014
4J8F	Crystal structure of a fusion protein containing the NBD of Hsp70 and the middle domain of Hip 分子名称: ADENOSINE-5'-DIPHOSPHATE, Heat shock 70 kDa protein 1A/1B, Hsc70-interacting protein, ... 著者 Li, Z, Bracher, A. 登録日 2013-02-14 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle. Nat.Struct.Mol.Biol., 20, 2013
4HGJ	Crystal structure of P450 BM3 5F5 heme domain variant 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450/NADPH-P450 reductase, GLYCEROL, ... 著者 Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. 登録日 2012-10-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
4H6W	Structure of Prenylagaramide maturation protease PagA 分子名称: N-terminal cyanobactin protease 著者 Nair, S.K, Agarwal, V. 登録日 2012-09-19 公開日 2012-10-03 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chem.Biol., 19, 2012
4J54	Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical isolate PR20 with the potent antiviral inhibitor GRL-0519A 分子名称: (3R,3aS,3bR,6aS,7aS)-octahydrodifuro[2,3-b:3',2'-d]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, ACETATE ION, IODIDE ION, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2013-02-07 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Extreme Multidrug Resistant HIV-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1'-Pyrrolidinone or P2-Tris-tetrahydrofuran. J.Med.Chem., 56, 2013
4GNY	Bovine beta-lactoglobulin complex with dodecyl sulfate 分子名称: Beta-lactoglobulin, DODECYL SULFATE, GLYCEROL 著者 Gutierrez-Magdaleno, G, Torres-Rivera, A, Garcia-Hernandez, E, Rodriguez-Romero, A. 登録日 2012-08-17 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6367 Å) 主引用文献 Ligand-binding and self-association cooperativity of beta-lactoglobulin J.Mol.Recognit., 26, 2013
3WYO	Heterodimeric myoglobin formed by domain swapping 分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE 著者 Lin, Y.W, Nagao, S, Zhang, M, Shomura, Y, Higuchi, Y, Hirota, S. 登録日 2014-09-04 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rational design of heterodimeric protein using domain swapping for myoglobin. Angew.Chem.Int.Ed.Engl., 54, 2015
3F49	Anion-triggered Engineered Subtilisin SUBT_BACAM 分子名称: SODIUM ION, Subtilisin BPN 著者 Gallagher, D.T, Bryan, P.N. 登録日 2008-10-31 公開日 2008-12-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Anion-triggered Engineered Subtilisin SUBT_BACAM To be Published
4H94	Radiation damage in lysozyme - 0.56 MGy 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Sutton, K.A, Snell, E.H. 登録日 2012-09-24 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
4GQS	Structure of Human Microsomal Cytochrome P450 (CYP) 2C19 分子名称: (4-hydroxy-3,5-dimethylphenyl)(2-methyl-1-benzofuran-3-yl)methanone, Cytochrome P450 2C19, GLYCEROL, ... 著者 Reynald, R.L, Sansen, S, Stout, C.D, Johnson, E.F. 登録日 2012-08-23 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Structural Characterization of Human Cytochrome P450 2C19: ACTIVE SITE DIFFERENCES BETWEEN P450s 2C8, 2C9, AND 2C19. J.Biol.Chem., 287, 2012
4JJC	Crystal structure of the Abl-SH3 domain at pH5 分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH5 To be Published
4GZL	Crystal structure of RAC1 Q61L mutant 分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Ha, B.H, Boggon, T.J. 登録日 2012-09-06 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc.Natl.Acad.Sci.USA, 110, 2013
4GZW	N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with avian sialic acid receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
4JK5	Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Ser) 分子名称: 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... 著者 Buth, S.A, Leiman, P.G, Chen, S, Heinis, C. 登録日 2013-03-09 公開日 2013-07-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids. Chembiochem, 14, 2013
4BQL	Crystal structure of archaeal actin 分子名称: ACTIN/ACTIN FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Lindaas, A.-C, Chruszsz, M, Bernander, R, Valegard, K. 登録日 2013-05-31 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Structure of Crenactin, an Archaeal Actin Homologue Active at 90Degc. Acta Crystallogr.,Sect.D, 70, 2014
3G5H	Crystallographic analysis of cytochrome P450 cyp121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Belin, P, Le Du, M.H, Gondry, M. 登録日 2009-02-05 公開日 2009-04-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
4H52	Wild-type influenza N2 neuraminidase covalent complex with 3-fluoro-Neu5Ac 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CALCIUM ION, ... 著者 Vavricka, C.J, Liu, Y, Kiyota, H, Sriwilaijaroen, N, Qi, J, Tanaka, K, Wu, Y, Li, Q, Li, Y, Yan, J, Suzuki, Y, Gao, G.F. 登録日 2012-09-18 公開日 2013-02-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Influenza neuraminidase operates via a nucleophilic mechanism and can be targeted by covalent inhibitors Nat Commun, 4, 2013
3G93	Single ligand occupancy crystal structure of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole 分子名称: 1-(biphenyl-4-ylmethyl)-1H-imidazole, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Gay, S.C, Sun, L, Maekawa, K, Halpert, J.R, Stout, C.D. 登録日 2009-02-12 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. Biochemistry, 48, 2009
3G8H	Crystal structure of phospholipase A2 ammodytoxin C from vipera ammodytes ammodytes 分子名称: Phospholipase A2, ammodytoxin C, SULFATE ION 著者 Saul, F.A, Faure, G. 登録日 2009-02-12 公開日 2009-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity J.Struct.Biol., 169, 2010
3G8K	Crystal structure of murine natural killer cell receptor, Ly49L4 分子名称: Lectin-related NK cell receptor LY49L1 著者 Cho, S. 登録日 2009-02-12 公開日 2009-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity, 31, 2009
3G8S	Crystal structure of the pre-cleaved Bacillus anthracis glmS ribozyme 分子名称: GLMS RIBOZYME, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ... 著者 Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. 登録日 2009-02-12 公開日 2009-11-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme Biochemistry, 48, 2009
4JP9	Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors 分子名称: (4R)-2'-amino-6-(3-chlorophenyl)-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one, Beta-secretase 1, NICKEL (II) ION 著者 Vigers, G.P.A, Smith, D. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid beta in a higher species. J.Med.Chem., 56, 2013

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