PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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5PAI	human factor VIIa in complex with N-(2-amino-1H-benzimidazol-5-yl)-1-[3-[[(3,5-dimethyl-1,2-oxazol-4-yl)carbamoylamino]methyl]phenyl]-5-hydroxypyrazole-4-carboxamide at 1.73A 分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAE	Crystal Structure of Factor VIIa in complex with (2S)-2-hydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide 分子名称: (2S)-2-hydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide, CALCIUM ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAV	Crystal Structure of Factor VIIa in complex with N-(6-aminopyridin-3-yl)-5-hydroxy-1-phenylpyrazole-4-carboxamide 分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PB6	Crystal Structure of Factor VIIa in complex with N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]pentanamide 分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-16 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAO	Crystal Structure of Factor VIIa in complex with (2S)-2,3-dihydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide;hydrobromide 分子名称: (2S)-2,3-dihydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAN	Crystal Structure of Factor VIIa in complex with 5-hydroxy-N-(3-oxo-1,2-dihydroisoindol-5-yl)-1-[3-[(phenylcarbamoylamino)methyl]phenyl]pyrazole-4-carboxamide 分子名称: 5-hydroxy-N-(1-oxo-1H-isoindol-6-yl)-1-(3-{[(phenylcarbamoyl)amino]methyl}phenyl)-1H-pyrazole-4-carboxamide, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAU	Crystal Structure of Factor VIIa in complex with N-(2-amino-1H-benzimidazol-5-yl)-2-[3-[(2-amino-2-oxoethyl)-methylsulfonylamino]phenyl]acetamide;2,2,2-trifluoroacetic acid 分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAK	Crystal Structure of Factor VIIa in complex with N-[[4-(aminomethyl)-2-(2-amino-2-oxoethoxy)phenyl]methyl]-2-(4-hydroxyphenyl)-2-methoxyacetamide;hydrochloride 分子名称: (2~{S})-~{N}-[[4-(aminomethyl)-2-(2-azanyl-2-oxidanylidene-ethoxy)phenyl]methyl]-2-(4-hydroxyphenyl)-2-methoxy-ethanami de, CALCIUM ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PB5	human factor VIIa in complex with 1-[[3-[5-hydroxy-4-(7H-pyrrolo[2,3-d]pyrimidin-6-yl)pyrazol-1-yl]phenyl]methyl]-3-phenylurea at 1.84A 分子名称: CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-16 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAA	Crystal Structure of Factor VIIa in complex with cyclohexylmethanamine 分子名称: AMINOMETHYLCYCLOHEXANE, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAM	Crystal Structure of Factor VIIa in complex with 2-[(1-aminoisoquinolin-6-yl)amino]-2-(5-ethoxy-2-fluorophenyl)-1-(2-phenylpyrrolidin-1-yl)ethanone 分子名称: (2~{R})-2-[(1-azanylisoquinolin-6-yl)amino]-2-(5-ethoxy-2-fluoranyl-phenyl)-1-[(2~{R})-2-phenylpyrrolidin-1-yl]ethanone, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PB0	Crystal Structure of Factor VIIa in complex with 2-(4-ethoxy-3-methoxyphenyl)-2-(isoquinolin-6-ylamino)acetic acid 分子名称: (2~{R})-2-(4-ethoxy-3-methoxy-phenyl)-2-(isoquinolin-6-ylamino)ethanoic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAB	Crystal Structure of Factor VIIa in complex with 1-[[3-[2-hydroxy-3-(1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenylurea 分子名称: 1-[[3-[2-oxidanyl-3-(1~{H}-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenyl-urea, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
5PAR	Crystal Structure of Factor VIIa in complex with 1H-benzimidazol-2-amine 分子名称: 1H-benzimidazol-2-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. 登録日 2016-11-10 公開日 2017-06-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of a Factor VIIa complex To be published
7NXG	Wax synthase 1 from Acinetobacter baylyi (AbWSD1) co-crystallized with myristic acid 分子名称: MYRISTIC ACID, O-acyltransferase WSD 著者 Vollheyde, K, Kuehnel, K, Lambrecht, F, Kawelke, S, Herrfurth, C, Feussner, I. 登録日 2021-03-18 公開日 2022-03-30 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of the Bifunctional Wax Synthase 1 from Acinetobacter baylyi Suggests a Conformational Change upon Substrate Binding and Formation of Additional Substrate Binding Sites Acs Catalysis, 12, 2022
8D4U	Crystal Structure of Neutrophil Elastase Inhibited by Eap2 from S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular Adherence Protein, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
8D4Q	Crystal Structure of Neutrophil Elastase Inhibited by Eap1 from S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Extracellular Adherence Protein, Neutrophil elastase 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
8D4S	Crystal Structure of Cathepsin G Inhibited by Eap1 from S. aureus 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cathepsin G, C-terminal truncated form, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023
8D7I	Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus 分子名称: Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-07 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap1 from S. aureus To Be Published
8D7K	Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus 分子名称: Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-07 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Bifunctional Inhibition of Neutrophil Elastase and Cathepsin G by Eap2 from S. aureus To Be Published
8CN9	Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII 分子名称: CALCIUM ION, CESIUM ION, Coagulation factor VII, ... 著者 Schluckebier, G, Johansson, E. 登録日 2023-02-22 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders Nat Cardiovasc Res, 2023
8DEA	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: 1-[(3-acetylphenyl)acetyl]-N-(6-bromopyridin-2-yl)-L-prolinamide, Complement factor D, GLYCEROL 著者 Raman, K, Babu, Y.S. 登録日 2022-06-20 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.214 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
8DG6	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: 1-{2-[(2S)-2-{[(3-chloro-2-fluorophenyl)methyl]carbamoyl}pyrrolidin-1-yl]-2-oxoethyl}-1H-indazole-3-carboxamide, Complement factor D 著者 Raman, K, Babu, Y.S. 登録日 2022-06-23 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.986 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
8D95	Scaffold Hopping via Ring Opening Enables Identification of Acyclic Compounds as New Complement Factor D Inhibitors 分子名称: Complement factor D, N-(6-bromopyridin-2-yl)-1-[(3-cyanophenyl)acetyl]-L-prolinamide 著者 Raman, K, Babu, Y.S. 登録日 2022-06-09 公開日 2022-11-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.166 Å) 主引用文献 Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors. Bioorg.Med.Chem., 74, 2022
8D4V	Crystal Structure of Cathepsin G Inhibited by Eap2 from S. aureus 分子名称: Cathepsin G, C-terminal truncated form, Extracellular Adherence Protein, ... 著者 Gido, C.D, Herdendorf, T.J, Geisbrecht, B.V. 登録日 2022-06-02 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Characterization of two distinct neutrophil serine protease-binding modes within a Staphylococcus aureus innate immune evasion protein family. J.Biol.Chem., 299, 2023

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