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5PAM

Crystal Structure of Factor VIIa in complex with 2-[(1-aminoisoquinolin-6-yl)amino]-2-(5-ethoxy-2-fluorophenyl)-1-(2-phenylpyrrolidin-1-yl)ethanone

Summary for 5PAM
Entry DOI10.2210/pdb5pam/pdb
Group depositionCrystal Structures of Factor VIIa Complexes (G_1002015)
DescriptorCoagulation factor VII light chain, Coagulation factor VII heavy chain, CHLORIDE ION, ... (8 entities in total)
Functional Keywordsglycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (Human)
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Cellular locationSecreted: P08709 P08709
Total number of polymer chains2
Total formula weight35999.42
Authors
Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2021-11-17)
Primary citationMayweg, A.,Roever, S.,Rudolph, M.G.
Crystal Structure of a Factor VIIa complex
To be published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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