Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | GLY196 |
| A | LYS197 |
| A | ILE198 |
| A | LEU201 |
| A | GLU202 |
| B | HIS411 |
| B | GLY414 |
| B | THR415 |
| B | TRP416 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG173 |
| A | CYS174 |
| A | SER179 |
| A | LEU180 |
| A | HOH403 |
| A | HOH405 |
| A | HOH406 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | GLU270 |
| B | ASP272 |
| B | GLU275 |
| B | GLU280 |
| B | HOH647 |
| B | HOH789 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 502 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 503 |
| Chain | Residue |
| B | ARG262 |
| B | GLY458 |
| B | VAL459 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | MET366 |
| B | THR367 |
| B | ARG439 |
| B | HOH624 |
| B | HOH637 |
| B | HOH645 |
| B | HOH744 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue 7Z1 B 505 |
| Chain | Residue |
| B | HIS253 |
| B | ASP256 |
| B | THR298 |
| B | THR299 |
| B | ASP302 |
| B | ASP398 |
| B | SER399 |
| B | SER404 |
| B | SER423 |
| B | TRP424 |
| B | GLY425 |
| B | GLN426 |
| B | GLY427 |
| B | GLY435 |
| B | HOH607 |
| B | HOH691 |
Functional Information from PROSITE/UniProt
| site_id | PS01186 |
| Number of Residues | 16 |
| Details | EGF_2 EGF-like domain signature 2. CrCheGYslladgvsC |
| Chain | Residue | Details |
| A | CYS172-CYS187 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| B | VAL249-CYS254 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPHA |
| Chain | Residue | Details |
| B | ASP398-ALA409 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| B | HIS253 | |
| B | ASP302 | |
| B | SER404 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| B | ASP398 | |
| Chain | Residue | Details |
| B | ASN382 | |
