5PAB

Crystal Structure of Factor VIIa in complex with 1-[[3-[2-hydroxy-3-(1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenylurea

Summary for 5PAB

• Entry DOI: 10.2210/pdb5pab/pdb
• Group deposition: Crystal Structures of Factor VIIa Complexes (G_1002015)
• Descriptor: Coagulation factor VII heavy chain, Coagulation factor VII light chain, 1-[[3-[2-oxidanyl-3-(1~{H}-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenyl-urea, ... (8 entities in total)
• Functional Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P08709 P08709
• Total number of polymer chains: 2
• Total formula weight: 36245.59

Authors

Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2024-11-13)

• Primary citation: Mayweg, A.,Roever, S.,Rudolph, M.G.; Crystal Structure of a Factor VIIa complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.99 Å)