5PAB
Crystal Structure of Factor VIIa in complex with 1-[[3-[2-hydroxy-3-(1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenylurea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Coagulation factor VII heavy chain | polymer | 254 | 28119.3 | 1 | UniProt (P08709) Pfam (PF00089) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 2 | B (L) | Coagulation factor VII light chain | polymer | 64 | 6984.9 | 1 | UniProt (P08709) Pfam (PF14670) | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
| 3 | C (H) | 1-[[3-[2-oxidanyl-3-(1~{H}-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenyl-urea | non-polymer | 434.5 | 1 | Chemie (7XD) | |||
| 4 | D, I, J (H) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | E, F, G, L (H, L) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | H (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | K, M (H, L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 8 | N, O (H, L) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35104.2 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1141.4 | |
| All* | Total formula weight | 36245.6 |
