5PAE

Crystal Structure of Factor VIIa in complex with (2S)-2-hydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide

Summary for 5PAE

• Entry DOI: 10.2210/pdb5pae/pdb
• Group deposition: Crystal Structures of Factor VIIa Complexes (G_1002015)
• Descriptor: Coagulation factor VII light chain, Coagulation factor VII heavy chain, SULFATE ION, ... (7 entities in total)
• Functional Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: P08709 P08709
• Total number of polymer chains: 2
• Total formula weight: 36170.15

Authors

Stihle, M.,Mayweg, A.,Roever, S.,Rudolph, M.G. (deposition date: 2016-11-10, release date: 2017-06-21, Last modification date: 2024-10-23)

• Primary citation: Mayweg, A.,Roever, S.,Rudolph, M.G.; Crystal Structure of a Factor VIIa complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)