4V6D
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![BU of 4v6d by Molmil](/molmil-images/mine/4v6d) | Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | 登録日 | 2009-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
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4V8T
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![BU of 4v8t by Molmil](/molmil-images/mine/4v8t) | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | 分子名称: | 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... | 著者 | Greber, B.J, Boehringer, D, Montellese, C, Ban, N. | 登録日 | 2012-08-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
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4V7R
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![BU of 4v7r by Molmil](/molmil-images/mine/4v7r) | Yeast 80S ribosome. | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Ben-Shem, A, Jenner, L, Yusupova, G, Yusupov, M. | 登録日 | 2010-07-23 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Crystal structure of the eukaryotic ribosome. Science, 330, 2010
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4V9N
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![BU of 4v9n by Molmil](/molmil-images/mine/4v9n) | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | 分子名称: | 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F. | 登録日 | 2013-04-26 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2. Structure, 21, 2013
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4WR6
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![BU of 4wr6 by Molmil](/molmil-images/mine/4wr6) | Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2014-10-23 | 公開日 | 2015-06-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4TUA
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![BU of 4tua by Molmil](/molmil-images/mine/4tua) | |
4TUC
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![BU of 4tuc by Molmil](/molmil-images/mine/4tuc) | |
7UPH
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![BU of 7uph by Molmil](/molmil-images/mine/7uph) | Structure of a ribosome with tethered subunits | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Kim, D.S, Watkins, A, Bidstrup, E, Lee, J, Topkar, V.V, Kofman, C, Schwarz, K.J, Liu, Y, Pintilie, G, Roney, E, Das, R, Jewett, M.C. | 登録日 | 2022-04-15 | 公開日 | 2022-08-17 | 最終更新日 | 2022-08-31 | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | 主引用文献 | Three-dimensional structure-guided evolution of a ribosome with tethered subunits. Nat.Chem.Biol., 18, 2022
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8OHD
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![BU of 8ohd by Molmil](/molmil-images/mine/8ohd) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 3 (native) | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | 登録日 | 2023-03-21 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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7UG6
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![BU of 7ug6 by Molmil](/molmil-images/mine/7ug6) | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W. | 登録日 | 2022-03-24 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome. Nat.Struct.Mol.Biol., 30, 2023
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8OLT
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![BU of 8olt by Molmil](/molmil-images/mine/8olt) | Mitochondrial complex I from Mus musculus in the active state bound with piericidin A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-03-30 | 公開日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I. Sci Adv, 9, 2023
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8OM1
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![BU of 8om1 by Molmil](/molmil-images/mine/8om1) | Mitochondrial complex I from Mus musculus in the active state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Grba, D.N, Chung, I, Bridges, H.R, Agip, A.N.A, Hirst, J. | 登録日 | 2023-03-31 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I. Sci Adv, 9, 2023
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4TUD
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7TOP
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![BU of 7top by Molmil](/molmil-images/mine/7top) | Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20 | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7TOS
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![BU of 7tos by Molmil](/molmil-images/mine/7tos) | E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20 | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7TOR
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![BU of 7tor by Molmil](/molmil-images/mine/7tor) | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7TOQ
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![BU of 7toq by Molmil](/molmil-images/mine/7toq) | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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7U2J
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![BU of 7u2j by Molmil](/molmil-images/mine/7u2j) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-02-24 | 公開日 | 2022-07-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
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7U2H
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![BU of 7u2h by Molmil](/molmil-images/mine/7u2h) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, and deacylated E-site tRNAgly at 2.55A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-02-24 | 公開日 | 2022-07-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
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4U55
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![BU of 4u55 by Molmil](/molmil-images/mine/4u55) | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | 分子名称: | (14aR)-2,3,6-trimethoxy-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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4U4Q
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![BU of 4u4q by Molmil](/molmil-images/mine/4u4q) | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | 分子名称: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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7UQB
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![BU of 7uqb by Molmil](/molmil-images/mine/7uqb) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-19 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7UOO
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![BU of 7uoo by Molmil](/molmil-images/mine/7uoo) | Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... | 著者 | Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. | 登録日 | 2022-04-13 | 公開日 | 2023-03-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.34 Å) | 主引用文献 | rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
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7UW1
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![BU of 7uw1 by Molmil](/molmil-images/mine/7uw1) | A. baumannii 70S ribosome-Streptothricin-D complex | 分子名称: | 16s Ribosomal RNA, 23s ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Morgan, C.E, Yu, E.W. | 登録日 | 2022-05-02 | 公開日 | 2023-04-19 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.21 Å) | 主引用文献 | Streptothricin F is a bactericidal antibiotic effective against highly drug-resistant gram-negative bacteria that interacts with the 30S subunit of the 70S ribosome. Plos Biol., 21, 2023
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4U3U
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![BU of 4u3u by Molmil](/molmil-images/mine/4u3u) | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-22 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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