PDB: 2561 件ウェブページステータス検索Chemie searchBIRD

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8GFT	Hsp90 provides platform for CRaf dephosphorylation by PP5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... 著者 Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. 登録日 2023-03-08 公開日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Hsp90 provides a platform for kinase dephosphorylation by PP5. Nat Commun, 14, 2023
3VIU	Crystal structure of PurL from thermus thermophilus 分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Suzuki, S, Yanai, H, Kanagawa, M, Tamura, S, Watanabe, Y, Fuse, K, Baba, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-10-12 公開日 2012-01-18 最終更新日 2012-04-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 68, 2012
1GGM	GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH GLYCYL-ADENYLATE 分子名称: GLYCYL-ADENOSINE-5'-PHOSPHATE, Glycine--tRNA ligase 著者 Arnez, J.G, Moras, D. 登録日 1999-01-27 公開日 1999-01-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine. J.Mol.Biol., 286, 1999
7LHW	Structure of the LRRK2 monomer 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
7LI3	Structure of the LRRK2 G2019S mutant 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
7LI4	Structure of LRRK2 after symmetry expansion 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2 著者 Myasnikov, A, Zhu, H, Hixson, P, Xie, B, Yu, K, Pitre, A, Peng, J, Sun, J. 登録日 2021-01-26 公開日 2021-06-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural analysis of the full-length human LRRK2. Cell, 184, 2021
6O8C	Crystal structure of STING CTT in complex with TBK1 分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein 著者 Li, P, Zhao, B, Du, F. 登録日 2019-03-09 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature, 569, 2019
2QF7	Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli 分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ... 著者 St Maurice, M, Surinya, K.H, Rayment, I. 登録日 2007-06-27 公開日 2007-09-04 最終更新日 2012-02-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science, 317, 2007
6O8B	Crystal structure of STING CTD in complex with TBK1 分子名称: N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide, Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein 著者 Li, P, Zhao, B, Du, F. 登録日 2019-03-09 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature, 569, 2019
2C6O	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: CELL DIVISION PROTEIN KINASE 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-10 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg. Med. Chem. Lett., 16, 2006
2C6L	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: 4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-10 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar. Bioorg.Med.Chem.Lett., 16, 2006
2C6T	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-11 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar. Bioorg.Med.Chem.Lett., 16, 2006
2C6M	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-10 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar. Bioorg.Med.Chem.Lett., 16, 2006
1KMM	HISTIDYL-TRNA SYNTHETASE COMPLEXED WITH HISTIDYL-ADENYLATE 分子名称: HISTIDYL-ADENOSINE MONOPHOSPHATE, HISTIDYL-TRNA SYNTHETASE 著者 Arnez, J.G, Francklyn, C.S, Moras, D. 登録日 1997-05-09 公開日 1997-12-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase. Proc.Natl.Acad.Sci.USA, 94, 1997
4ODJ	Crystal structure of a putative S-adenosylmethionine synthetase from Cryptosporidium hominis in complex with S-adenosyl-methionine 分子名称: MAGNESIUM ION, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-01-10 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of a putative S-adenosylmethionine synthetase from Cryptosporidium hominis in complex with S-adenosyl-methionine To be Published
4MV4	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Mg2 分子名称: 1,2-ETHANEDIOL, Biotin carboxylase, CHLORIDE ION, ... 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV3	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Bicarbonate 分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, Biotin carboxylase, ... 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
6CVU	Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine 分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ATP-dependent dethiobiotin synthetase BioD, SULFATE ION 著者 Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W. 登録日 2018-03-28 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.426 Å) 主引用文献 Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
4MV1	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with ADP and Phosphate 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, ... 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
8QCW	The crystal structure of the truncated form of Lotus japonicus kinase 1 分子名称: non-specific serine/threonine protein kinase 著者 Leonidas, D.D, Solovou, T. 登録日 2023-08-28 公開日 2024-02-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Biochemical and Structural Studies of LjSK1, a Lotus japonicus GSK3 beta /SHAGGY-like Kinase, Reveal Its Functional Role. J.Agric.Food Chem., 72, 2024
2OI4	Crystal structure of human PIM1 in complex with fluorinated ruthenium pyridocarbazole 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Maksimoska, J, Meggers, E. 登録日 2007-01-10 公開日 2007-04-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ruthenium half-sandwich complexes as protein kinase inhibitors: derivatization of the pyridocarbazole pharmacophore ligand. Org.Biomol.Chem., 5, 2007
4MV7	Crystal Structure of Biotin Carboxylase form Haemophilus influenzae in Complex with Phosphonoformate 分子名称: 1,2-ETHANEDIOL, Biotin carboxylase, PHOSPHONOFORMIC ACID 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV8	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Phosphate 分子名称: Biotin carboxylase, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV6	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Phosphonoacetamide 分子名称: 1,2-ETHANEDIOL, Biotin carboxylase, PHOSPHONOACETAMIDE 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV9	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Bicarbonate 分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, Biotin carboxylase 著者 Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. 登録日 2013-09-23 公開日 2015-01-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015

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