7LHW

Structure of the LRRK2 monomer

Summary for 7LHW

• Entry DOI: 10.2210/pdb7lhw/pdb
• EMDB information: 23352
• Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2, GUANOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: parkinson's disease, microtubule, kinase, cryo-em, neuropeptide, transferase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 287378.04

Authors

Myasnikov, A.,Zhu, H.,Hixson, P.,Xie, B.,Yu, K.,Pitre, A.,Peng, J.,Sun, J. (deposition date: 2021-01-26, release date: 2021-06-16, Last modification date: 2024-03-06)

• Primary citation: Myasnikov, A.,Zhu, H.,Hixson, P.,Xie, B.,Yu, K.,Pitre, A.,Peng, J.,Sun, J.; Structural analysis of the full-length human LRRK2.; Cell, 184:3519-, 2021; PubMed: 34107286; DOI: 10.1016/j.cell.2021.05.004

Experimental method

ELECTRON MICROSCOPY (3.7 Å)