PDB: 98225 件ウェブページステータス検索Chemie searchBIRD

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1KBA	CRYSTAL STRUCTURE OF KAPPA-BUNGAROTOXIN AT 2.3-ANGSTROM RESOLUTION 分子名称: KAPPA-BUNGAROTOXIN 著者 Dewan, J.C, Grant, G.A, Sacchettini, J.C. 登録日 1994-07-13 公開日 1994-12-20 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of kappa-bungarotoxin at 2.3-A resolution. Biochemistry, 33, 1994
4QOZ	Crystal structure of the histone mRNA stem-loop, stem-loop binding protein (phosphorylated), and 3'hExo ternary complex 分子名称: 3'-5' exoribonuclease 1, Histone RNA hairpin-binding protein, histone mRNA stem-loop 著者 Tan, D, Tong, L. 登録日 2014-06-21 公開日 2014-07-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation. Proc.Natl.Acad.Sci.USA, 111, 2014
4JPC	Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors 分子名称: 3-[(4R)-2'-amino-1',2,2-trimethyl-5'-oxo-1',2,3,5'-tetrahydrospiro[chromene-4,4'-imidazol]-6-yl]benzonitrile, Beta-secretase 1, NICKEL (II) ION 著者 Vigers, G.P.A, Smith, D. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid beta in a higher species. J.Med.Chem., 56, 2013
1NCT	TITIN MODULE M5, N-TERMINALLY EXTENDED, NMR 分子名称: TITIN 著者 Pfuhl, M, Pastore, A. 登録日 1996-08-13 公開日 1996-11-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 When a module is also a domain: the role of the N terminus in the stability and the dynamics of immunoglobulin domains from titin. J.Mol.Biol., 265, 1997
4J8Z	Crystal Structure of the Human SPOP BTB Domain 分子名称: Speckle-type POZ protein 著者 Stead, M.A, Wright, S.C. 登録日 2013-02-15 公開日 2013-09-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP Acta Crystallogr.,Sect.D, 69, 2013
1IA9	CRYSTAL STRUCTURE OF THE ATYPICAL PROTEIN KINASE DOMAIN OF A TRP CA-CHANNEL, CHAK (AMPPNP COMPLEX) 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TRANSIENT RECEPTOR POTENTIAL-RELATED PROTEIN, ... 著者 Yamaguchi, H, Matsushita, M, Nairn, A.C, Kuriyan, J. 登録日 2001-03-22 公開日 2001-06-06 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol.Cell, 7, 2001
3ENL	REFINED STRUCTURE OF YEAST APO-ENOLASE AT 2.25 ANGSTROMS RESOLUTION 分子名称: ENOLASE, SULFATE ION 著者 Lebioda, L, Stec, B. 登録日 1990-11-13 公開日 1992-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Refined structure of yeast apo-enolase at 2.25 A resolution. J.Mol.Biol., 211, 1990
4JP9	Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors 分子名称: (4R)-2'-amino-6-(3-chlorophenyl)-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one, Beta-secretase 1, NICKEL (II) ION 著者 Vigers, G.P.A, Smith, D. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid beta in a higher species. J.Med.Chem., 56, 2013
3CLB	Structure of bifunctional TcDHFR-TS in complex with TMQ 分子名称: 1,2-ETHANEDIOL, DHFR-TS, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Schormann, N, Senkovich, O, Chattopadhyay, D. 登録日 2008-03-18 公開日 2009-01-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function. Proteins, 73, 2008
3R1G	Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody 分子名称: Beta-secretase 1, FAB of YW412.8.31 antibody heavy chain, FAB of YW412.8.31 antibody light chain 著者 Wang, W, Rouge, L, Wu, P, Chiu, C, Chen, Y, Wu, Y, Watts, R.J. 登録日 2011-03-10 公開日 2011-06-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo. Sci Transl Med, 3, 2011
1IFG	CRYSTAL STRUCTURE OF A MONOMERIC FORM OF GENERAL PROTEASE INHIBITOR, ECOTIN IN ABSENCE OF A PROTEASE 分子名称: ECOTIN 著者 Eggers, C.T, Wang, S.X, Fletterick, R.J, Craik, C.S. 登録日 2001-04-12 公開日 2001-05-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The role of ecotin dimerization in protease inhibition. J.Mol.Biol., 308, 2001
2P32	Crystal structure of the C-terminal 10 kDa subdomain from C. elegans Hsp70 分子名称: Heat shock 70 kDa protein A, SULFATE ION 著者 Worrall, L.J, Walkinshaw, M.D. 登録日 2007-03-08 公開日 2007-04-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the C-terminal three-helix bundle subdomain of C. elegans Hsp70. Biochem.Biophys.Res.Commun., 357, 2007
1IIC	Crystal Structure of Saccharomyces cerevisiae N-myristoyltransferase with Bound MyristoylCoA 分子名称: PEPTIDE N-myristoyltransferase, TETRADECANOYL-COA 著者 Farazi, T.A, Waksman, G, Gordon, J.I. 登録日 2001-04-22 公開日 2001-05-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry, 40, 2001
1J2Q	20S proteasome in complex with calpain-Inhibitor I from archaeoglobus fulgidus 分子名称: 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID [1-(1-FORMYL-PENTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE, Proteasome alpha subunit, Proteasome beta subunit 著者 Groll, M, Brandstetter, H, Bartunik, H, Bourenkow, G, Huber, R. 登録日 2003-01-08 公開日 2003-03-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Investigations on the Maturation and Regulation of Archaebacterial Proteasomes J.MOL.BIOL., 327, 2003
2LXP	NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g 分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION 著者 Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. 登録日 2012-08-30 公開日 2013-08-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
2LXH	NMR structure of the RING domain in ubiquitin ligase gp78 分子名称: E3 ubiquitin-protein ligase AMFR, ZINC ION 著者 Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R. 登録日 2012-08-27 公開日 2013-08-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
1SEP	MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND SEPIAPTERIN 分子名称: BIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SEPIAPTERIN REDUCTASE 著者 Auerbach, G, Herrmann, A, Guetlich, M, Fischer, M, Jacob, U, Bacher, A, Huber, R. 登録日 1997-05-23 公開日 1999-01-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J., 16, 1997
1SPI	CRYSTAL STRUCTURE OF SPINACH CHLOROPLAST FRUCTOSE-1,6-BISPHOSPHATASE AT 2.8 ANGSTROMS RESOLUTION 分子名称: FRUCTOSE 1,6-BISPHOSPHATASE 著者 Villeret, V, Huang, S, Zhang, Y, Xue, Y, Lipscomb, W.N. 登録日 1994-12-14 公開日 1995-02-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of spinach chloroplast fructose-1,6-bisphosphatase at 2.8 A resolution. Biochemistry, 34, 1995
6TIR	NOE based model of hVDAC-1 bound to beta-NADH in detergent micelles 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Voltage-dependent anion-selective channel protein 1 著者 Boehm, R, Hiller, S, Wagner, G. 登録日 2019-11-22 公開日 2019-12-04 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Structural Basis for Low Conductance in the Membrane Protein VDAC upon beta-NADH Binding and Voltage Gating. Structure, 28, 2020
1EQW	CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM CU,ZN SUPEROXIDE DISMUTASE 分子名称: COPPER (II) ION, CU,ZN SUPEROXIDE DISMUTASE, ZINC ION 著者 Pesce, A, Battistoni, A, Stroppolo, M.E, Polizio, F, Nardini, M, Kroll, J.S, Langford, P.R, O'Neill, P, Sette, M, Desideri, A, Bolognesi, M. 登録日 2000-04-06 公開日 2000-09-08 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene. J.Mol.Biol., 302, 2000
6GX9	Crystal structure of the TNPO3 - CPSF6 RSLD complex 分子名称: BENZAMIDINE, BICINE, Cleavage and polyadenylation specificity factor subunit 6, ... 著者 Cherepanov, P, Cook, N. 登録日 2018-06-26 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6. Nucleic Acids Res., 47, 2019
6TU3	Rat 20S proteasome 分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... 著者 Deshmukh, F.K, Polkinghorn, C.R, Elad, N, Sharon, M. 登録日 2020-01-02 公開日 2020-05-13 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry. Acs Cent.Sci., 6, 2020
317D	STRUCTURE OF D(CCTAGGG): COMPARISON WITH NINE ISOMORPHOUS OCTAMER SEQUENCES REVEALS FOUR DISTINCT PATTERNS OF SEQUENCE-DEPENDENT INTERMOLECULAR INTERACTIONS 分子名称: DNA (5'-D(*CP*CP*CP*TP*AP*GP*GP*G)-3') 著者 Tippin, D.B, Sundaralingam, M. 登録日 1997-03-17 公開日 1997-05-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of d(CCCTAGGG): comparison with nine isomorphous octamer sequences reveals four distinct patterns of sequence-dependent intermolecular interactions. Acta Crystallogr.,Sect.D, 52, 1996
5T19	Structure of PTP1B complexed with N-(3'-(1,1-dioxido-4-oxo-1,2,5-thiadiazolidin-2-yl)-4'-methyl-[1,1'-biphenyl]-4-yl)acetamide 分子名称: 5-[4-methyl-4'-(methylamino)[1,1'-biphenyl]-3-yl]-1lambda~6~,2,5-thiadiazolidine-1,1,3-trione, CHLORIDE ION, MAGNESIUM ION, ... 著者 Laciak, A.R, Tanner, J.J. 登録日 2016-08-18 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1001 Å) 主引用文献 Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) by an Inhibitor-Electrophile Conjugate. Biochemistry, 56, 2017
344D	DETERMINATION BY MAD-DM OF THE STRUCTURE OF THE DNA DUPLEX D(ACGTACG(5-BRU))2 AT 1.46A AND 100K 分子名称: DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*(BRU))-3') 著者 Todd, A.R, Adams, A, Powell, H.R, Cardin, C.J. 登録日 1997-08-04 公開日 1997-09-26 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Determination by MAD-DM of the structure of the DNA duplex d[ACGTACG(5-BrU)]2 at 1.46 A and 100 K. Acta Crystallogr.,Sect.D, 55, 1999

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