PDB: 1446 件ウェブページステータス検索Chemie searchBIRD

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6HKO	Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Weis, F, Muller, C.W. 登録日 2018-09-07 公開日 2019-04-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
5W5Y	RNA polymerase I Initial Transcribing Complex 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Han, Y, He, Y. 登録日 2017-06-16 公開日 2017-07-26 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
5W66	RNA polymerase I Initial Transcribing Complex State 3 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Han, Y, He, Y. 登録日 2017-06-16 公開日 2017-07-26 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Elife, 6, 2017
6HLS	Yeast apo RNA polymerase I* 分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... 著者 Tafur, L, Sadian, Y, Weis, F, Muller, C.W. 登録日 2018-09-11 公開日 2019-04-03 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
6EXV	Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin 分子名称: AMATOXIN, DNA (25-MER), DNA (36-MER), ... 著者 Liu, X, Farnung, L, Wigge, C, Cramer, P. 登録日 2017-11-09 公開日 2018-03-21 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin. J. Biol. Chem., 293, 2018
3FKI	12-Subunit RNA Polymerase II Refined with Zn-SAD data 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Meyer, P.A, Ye, P, Suh, M.H, Zhang, M, Fu, J. 登録日 2008-12-16 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.88 Å) 主引用文献 Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data J.Biol.Chem., 284, 2009
1NT9	Complete 12-subunit RNA polymerase II 分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ... 著者 Armache, K.-J, Kettenberger, H, Cramer, P. 登録日 2003-01-29 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Architecture of initiation-competent 12-subunit RNA polymerase II Proc.Natl.Acad.Sci.USA, 100, 2003
1PQV	RNA polymerase II-TFIIS complex 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... 著者 Kettenberger, H, Armache, K.-J, Cramer, P. 登録日 2003-06-19 公開日 2003-08-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Architecture of the RNA Polymerase II-TFIIS Complex and Implications for mRNA Cleavage Cell(Cambridge,Mass.), 114, 2003
4BXZ	RNA Polymerase II-Bye1 complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. 登録日 2013-07-16 公開日 2013-09-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.8 Å) 主引用文献 Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
8UKR	RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKU	RNA polymerase II elongation complex with Fapy-dG lesion with CMP added 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKT	RNA polymerase II elongation complex with Fapy-dG lesion with AMP added 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKQ	RNA polymerase II elongation complex with Fapy-dG lesion in apo state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKS	RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
1R9T	RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA nontemplate strand, DNA template strand, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2003-10-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
6INQ	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position) 分子名称: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-10-26 公開日 2019-04-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
7WBW	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3.5) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7WBV	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome 分子名称: DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7WBX	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7OQY	Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase 分子名称: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... 著者 Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. 登録日 2021-06-04 公開日 2021-08-25 最終更新日 2021-11-03 実験手法 ELECTRON MICROSCOPY (2.61 Å) 主引用文献 Structural basis of RNA polymerase inhibition by viral and host factors. Nat Commun, 12, 2021
8S5N	RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. 登録日 2024-02-24 公開日 2024-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Three-step mechanism of promoter escape by RNA polymerase II. Mol.Cell, 84, 2024
7OQ4	Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase 分子名称: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... 著者 Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. 登録日 2021-06-02 公開日 2021-08-25 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structural basis of RNA polymerase inhibition by viral and host factors. Nat Commun, 12, 2021
1TWH	RNA polymerase II complexed with 2'dATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2004-06-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
1TWF	RNA polymerase II complexed with UTP at 2.3 A resolution 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2004-06-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
1TWC	RNA polymerase II complexed with GTP 分子名称: DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2004-06-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004

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