8UFI
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![BU of 8ufi by Molmil](/molmil-images/mine/8ufi) | Cryo-EM structure of bovine phosphodiesterase 6 | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | 著者 | Aplin, C, Cerione, R.A. | 登録日 | 2023-10-04 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. J.Biol.Chem., 300, 2023
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8UGB
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![BU of 8ugb by Molmil](/molmil-images/mine/8ugb) | Cryo-EM structure of bovine phosphodiesterase 6 bound to udenafil | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | 著者 | Aplin, C, Cerione, R.A. | 登録日 | 2023-10-05 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. J.Biol.Chem., 300, 2023
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8UGS
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![BU of 8ugs by Molmil](/molmil-images/mine/8ugs) | Cryo-EM structure of bovine phosphodiesterase 6 bound to cGMP | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, MAGNESIUM ION, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... | 著者 | Aplin, C, Cerione, R.A. | 登録日 | 2023-10-06 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. J.Biol.Chem., 300, 2023
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8ULG
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![BU of 8ulg by Molmil](/molmil-images/mine/8ulg) | |
3JBQ
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![BU of 3jbq by Molmil](/molmil-images/mine/3jbq) | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6 | 分子名称: | GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, IgG1-kappa 2E8 heavy chain, ... | 著者 | Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A. | 登録日 | 2015-09-17 | 公開日 | 2015-09-30 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6. J.Biol.Chem., 290, 2015
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8BOR
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![BU of 8bor by Molmil](/molmil-images/mine/8bor) | Photosensory module from DrBphP without PHY tongue | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | 著者 | Kurttila, M, Takala, H, Ihalainen, J.A. | 登録日 | 2022-11-15 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The interconnecting hairpin extension "arm": An essential allosteric element of phytochrome activity. Structure, 31, 2023
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3JAB
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![BU of 3jab by Molmil](/molmil-images/mine/3jab) | Domain organization and conformational plasticity of the G protein effector, PDE6 | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, GafA domain of cone phosphodiesterase 6C, GafB domain of phosphodiesterase 2A, ... | 著者 | Zhang, Z, He, F, Constantine, R, Baker, M.L, Baehr, W, Schmid, M.F, Wensel, T.G, Agosto, M.A. | 登録日 | 2015-05-26 | 公開日 | 2015-06-10 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6. J.Biol.Chem., 290, 2015
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8ISI
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![BU of 8isi by Molmil](/molmil-images/mine/8isi) | Photochromobilin-free form of Arabidopsis thaliana phytochrome A - apo-AtphyA | 分子名称: | Phytochrome A | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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8ISK
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![BU of 8isk by Molmil](/molmil-images/mine/8isk) | Pr conformer of Zea mays phytochrome A1 - ZmphyA1-Pr | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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5LLY
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![BU of 5lly by Molmil](/molmil-images/mine/5lly) | Photosensory Module of Bacteriophytochrome linked Diguanylyl Cyclase from Idiomarina species A28L | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein, ... | 著者 | Gourinchas, G, Winkler, A. | 登録日 | 2016-07-28 | 公開日 | 2017-03-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Long-range allosteric signaling in red light-regulated diguanylyl cyclases. Sci Adv, 3, 2017
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8IFF
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![BU of 8iff by Molmil](/molmil-images/mine/8iff) | Cryo-EM structure of Arabidopsis phytochrome A. | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | 著者 | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | 登録日 | 2023-02-17 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Plant phytochrome A in the Pr state assembles as an asymmetric dimer. Cell Res., 33, 2023
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8ISJ
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![BU of 8isj by Molmil](/molmil-images/mine/8isj) | Pr conformer of Arabidopsis thaliana phytochrome A - AtphyA-Pr | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | 著者 | Zhang, Y, Ma, C, Zhao, J, Gao, N, Wang, J. | 登録日 | 2023-03-20 | 公開日 | 2023-08-09 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural insights into plant phytochrome A as a highly sensitized photoreceptor. Cell Res., 33, 2023
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7JSN
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![BU of 7jsn by Molmil](/molmil-images/mine/7jsn) | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6 | 分子名称: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A. | 登録日 | 2020-08-15 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6. Mol.Cell, 80, 2020
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5LLX
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![BU of 5llx by Molmil](/molmil-images/mine/5llx) | Bacteriophytochrome activated diguanylyl cyclase from Idiomarina species A28L with GTP bound | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, CHLORIDE ION, Diguanylate cyclase (GGDEF) domain-containing protein, ... | 著者 | Gourinchas, G, Winkler, A. | 登録日 | 2016-07-28 | 公開日 | 2017-03-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Long-range allosteric signaling in red light-regulated diguanylyl cyclases. Sci Adv, 3, 2017
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8SGK
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![BU of 8sgk by Molmil](/molmil-images/mine/8sgk) | CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | 著者 | Li, H, Li, H. | 登録日 | 2023-04-12 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | CryoEM structure of Deinococcus radiodurans BphP photosensory module in Pr state To Be Published
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7L5A
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![BU of 7l5a by Molmil](/molmil-images/mine/7l5a) | Crystal structure of the photosensory module from Xanthomonas campestris bacteriophytochrome XccBphP in the Pfr state | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | 登録日 | 2020-12-21 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level. Sci Adv, 7, 2021
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7L59
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![BU of 7l59 by Molmil](/molmil-images/mine/7l59) | Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP-G454E variant from Xanthomonas campestris in the Pfr state | 分子名称: | BILIVERDINE IX ALPHA, Bacteriophytochrome | 著者 | Otero, L.H, Antelo, G, Sanchez-Lamas, M, Klinke, S, Goldbaum, F.A, Rinaldi, J, Bonomi, H.R. | 登録日 | 2020-12-21 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level. Sci Adv, 7, 2021
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6ET7
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![BU of 6et7 by Molmil](/molmil-images/mine/6et7) | |
6FHT
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![BU of 6fht by Molmil](/molmil-images/mine/6fht) | Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted Pr form | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Adenylate cyclase, DODECAETHYLENE GLYCOL, ... | 著者 | Etzl, S, Winkler, A. | 登録日 | 2018-01-15 | 公開日 | 2018-04-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications. J. Biol. Chem., 293, 2018
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6G1Z
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![BU of 6g1z by Molmil](/molmil-images/mine/6g1z) | Crystal structure of a fluorescence optimized bathy phytochrome PAiRFP2 derived from wild-type Agp2 in its Pfr state. | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, ... | 著者 | Sauthof, L, Schmidt, A, Szczepek, M, Scheerer, P. | 登録日 | 2018-03-22 | 公開日 | 2018-11-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural snapshot of a bacterial phytochrome in its functional intermediate state. Nat Commun, 9, 2018
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6G1Y
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![BU of 6g1y by Molmil](/molmil-images/mine/6g1y) | Crystal structure of the photosensory core module (PCM) of a bathy phytochrome from Agrobacterium fabrum in the Pfr state. | 分子名称: | 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome protein | 著者 | Schmidt, A, Qureshi, B.M, Scheerer, P. | 登録日 | 2018-03-22 | 公開日 | 2018-11-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural snapshot of a bacterial phytochrome in its functional intermediate state. Nat Commun, 9, 2018
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6G20
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![BU of 6g20 by Molmil](/molmil-images/mine/6g20) | Crystal structure of a fluorescence optimized bathy phytochrome PAiRFP2 derived from wild-type Agp2 in its functional Meta-F intermediate state. | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, ... | 著者 | Schmidt, A, Sauthof, L, Szczepek, M, Scheerer, P. | 登録日 | 2018-03-22 | 公開日 | 2018-11-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structural snapshot of a bacterial phytochrome in its functional intermediate state. Nat Commun, 9, 2018
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6BAP
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![BU of 6bap by Molmil](/molmil-images/mine/6bap) | Stigmatella aurantiaca bacterial phytochrome PAS-GAF-PHY, T289H mutant | 分子名称: | 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Photoreceptor-histidine kinase BphP | 著者 | Schmidt, M, Stojkovic, E. | 登録日 | 2017-10-14 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome. IUCrJ, 5, 2018
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6BAY
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![BU of 6bay by Molmil](/molmil-images/mine/6bay) | |
4GW9
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![BU of 4gw9 by Molmil](/molmil-images/mine/4gw9) | |