PDB: 249 件ウェブページステータス検索Chemie searchBIRD

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7ZDD	Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K10ac histone peptide. 分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM33, Histone H3.X, ... 著者 Caria, S, Duclos, S, Crespillo, S, Errey, J, Barker, J.J. 登録日 2022-03-29 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.625 Å) 主引用文献 Identification of Histone Peptide Binding Specificity and Small-Molecule Ligands for the TRIM33 alpha and TRIM33 beta Bromodomains. Acs Chem.Biol., 17, 2022
3U5P	Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide 分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A poised chromatin platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011
3U5N	Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide 分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION 著者 Wang, Z, Patel, D.J. 登録日 2011-10-11 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A Poised Chromatin Platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147, 2011
8I02	Cryo-EM structure of the SIN3S complex from S. pombe 分子名称: Chromatin modification-related protein eaf3, Cph1, Histone deacetylase clr6, ... 著者 Wang, C, Guo, Z, Zhan, X. 登録日 2023-01-10 公開日 2023-05-03 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Two assembly modes for SIN3 histone deacetylase complexes. Cell Discov, 9, 2023
4COS	Crystal structure of the PHD-Bromo-PWWP cassette of human PRKCBP1 分子名称: 1,4-DIETHYLENE DIOXIDE, PROTEIN KINASE C-BINDING PROTEIN 1, ZINC ION 著者 Krojer, T, Savitsky, P, Newman, J.A, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Filippakopoulos, P. 登録日 2014-01-30 公開日 2014-03-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin. Cell Rep, 17, 2016
6LTH	Structure of human BAF Base module 分子名称: AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020
4BXZ	RNA Polymerase II-Bye1 complex 分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... 著者 Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. 登録日 2013-07-16 公開日 2013-09-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.8 Å) 主引用文献 Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
6Q3M	Structure of CHD4 PHD2 - tandem chromodomains 分子名称: 1,2-ETHANEDIOL, Chromodomain-helicase-DNA-binding protein 4, DI(HYDROXYETHYL)ETHER, ... 著者 Alt, A, Mancini, E.J. 登録日 2018-12-04 公開日 2019-12-25 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Structure of histone readers To Be Published
2FSA	Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4ME2 bound state 分子名称: Histone H3(1-15)K4me2 peptide, ZINC ION, bromodomain PHD finger transcription factor 著者 Li, H, Patel, D.J. 登録日 2006-01-21 公開日 2006-07-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature, 442, 2006
6RYR	Nucleosome-CHD4 complex structure (single CHD4 copy) 分子名称: Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... 著者 Farnung, L, Ochmann, M, Cramer, P. 登録日 2019-06-11 公開日 2020-07-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
6LTJ	Structure of nucleosome-bound human BAF complex 分子名称: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020
6UGM	Structural basis of COMPASS eCM recognition of an unmodified nucleosome 分子名称: Bre2, DNA (146-MER), H3 N-terminus, ... 著者 Hsu, P.L, Shi, H, Zheng, N. 登録日 2019-09-26 公開日 2019-11-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Mol.Cell, 76, 2019
6VEN	Yeast COMPASS in complex with a ubiquitinated nucleosome 分子名称: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ... 著者 Worden, E.J, Wolberger, C. 登録日 2020-01-02 公開日 2020-01-15 最終更新日 2020-01-22 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome. Elife, 9, 2020
6MZL	Human TFIID canonical state 分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (23 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6RYU	Nucleosome-CHD4 complex structure (two CHD4 copies) 分子名称: Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... 著者 Farnung, L, Ochmann, M, Cramer, P. 登録日 2019-06-12 公開日 2020-07-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
6MZD	Human TFIID Lobe A canonical 分子名称: TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... 著者 Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. 登録日 2018-11-05 公開日 2018-11-28 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (9.8 Å) 主引用文献 Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
6UH5	Structural basis of COMPASS eCM recognition of the H2Bub nucleosome 分子名称: Bre2, DNA (146-MER), H3 N-terminus, ... 著者 Hsu, P.L, Shi, H, Zheng, N. 登録日 2019-09-26 公開日 2019-11-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS. Mol.Cell, 76, 2019
8W9E	Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 2 分子名称: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ... 著者 Wang, C, Zhan, X. 登録日 2023-09-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures and dynamics of Rpd3S complex bound to nucleosome. Sci Adv, 10, 2024
5B73	Crystal structure of human ZMYND8 PHD-Bromo-PWWP domain 分子名称: Protein kinase C-binding protein 1, ZINC ION 著者 Li, H, Li, Y, Zheng, X. 登録日 2016-06-03 公開日 2016-11-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes Mol.Cell, 63, 2016
8W9F	Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 3 分子名称: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ... 著者 Wang, C, Zhan, X. 登録日 2023-09-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structures and dynamics of Rpd3S complex bound to nucleosome. Sci Adv, 10, 2024
8W9D	Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 1 分子名称: 3-DNA, 5-DNA, Chromatin modification-related protein EAF3, ... 著者 Wang, C, Zhan, X. 登録日 2023-09-05 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures and dynamics of Rpd3S complex bound to nucleosome. Sci Adv, 10, 2024
6IET	The crystal structure of TRIM66 PHD-Bromo domain 分子名称: Tripartite motif-containing protein 66, ZINC ION 著者 Chen, J. 登録日 2018-09-17 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells. Nat Commun, 10, 2019
6IEU	The structure of TRIM66 PHD-Bromo domain with unmodified H3 N terminal peptide 分子名称: ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-LYS-SER-THR-GLY, GLYCEROL, Tripartite motif-containing protein 66, ... 著者 Chen, J. 登録日 2018-09-17 公開日 2019-09-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.787 Å) 主引用文献 TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells. Nat Commun, 10, 2019
5H1U	Complex structure of TRIM24 PHD-bromodomain and inhibitor 2 分子名称: 2-amino-1,3-benzothiazole-6-carboxamide, DIMETHYL SULFOXIDE, Transcription intermediary factor 1-alpha, ... 著者 Liu, J. 登録日 2016-10-11 公開日 2017-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network FEBS J., 284, 2017
5H1T	Complex structure of TRIM24 PHD-bromodomain and inhibitor 1 分子名称: DIMETHYL SULFOXIDE, Transcription intermediary factor 1-alpha, ZINC ION, ... 著者 Liu, J. 登録日 2016-10-11 公開日 2017-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network FEBS J., 284, 2017

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