8BCB
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![BU of 8bcb by Molmil](/molmil-images/mine/8bcb) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 34 | 分子名称: | 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, SULFANILAMIDE, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCA
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![BU of 8bca by Molmil](/molmil-images/mine/8bca) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 26 | 分子名称: | 1,2-ETHANEDIOL, 3-azanyl-~{N}-methyl-4-(methylamino)benzenesulfonamide, GLYCEROL, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCF
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![BU of 8bcf by Molmil](/molmil-images/mine/8bcf) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 78 | 分子名称: | 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCE
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![BU of 8bce by Molmil](/molmil-images/mine/8bce) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 76 | 分子名称: | 1,2-ETHANEDIOL, N-methoxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCG
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![BU of 8bcg by Molmil](/molmil-images/mine/8bcg) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 86 | 分子名称: | 1,2-ETHANEDIOL, 4-chloranyl-~{N}-methoxy-~{N}-methyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BC8
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![BU of 8bc8 by Molmil](/molmil-images/mine/8bc8) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 18 | 分子名称: | 1,2-ETHANEDIOL, 3-azanyl-4-oxidanyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCD
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![BU of 8bcd by Molmil](/molmil-images/mine/8bcd) | |
8BC9
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![BU of 8bc9 by Molmil](/molmil-images/mine/8bc9) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 24 | 分子名称: | 1,2-ETHANEDIOL, N-hydroxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | 著者 | Vester, K, Loll, B, Wahl, M.C. | 登録日 | 2022-10-15 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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3HIB
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![BU of 3hib by Molmil](/molmil-images/mine/3hib) | |
2F88
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![BU of 2f88 by Molmil](/molmil-images/mine/2f88) | |
5HHK
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![BU of 5hhk by Molmil](/molmil-images/mine/5hhk) | |
5HHJ
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![BU of 5hhj by Molmil](/molmil-images/mine/5hhj) | |
5HHL
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![BU of 5hhl by Molmil](/molmil-images/mine/5hhl) | |
5IRG
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![BU of 5irg by Molmil](/molmil-images/mine/5irg) | |
5IRF
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![BU of 5irf by Molmil](/molmil-images/mine/5irf) | |
1D3B
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![BU of 1d3b by Molmil](/molmil-images/mine/1d3b) | CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION | 分子名称: | CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ... | 著者 | Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K. | 登録日 | 1998-12-22 | 公開日 | 1999-12-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell(Cambridge,Mass.), 96, 1999
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5MF9
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![BU of 5mf9 by Molmil](/molmil-images/mine/5mf9) | Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide. | 分子名称: | RNA-binding protein 5, Survival motor neuron protein | 著者 | Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J. | 登録日 | 2016-11-17 | 公開日 | 2016-12-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation Elife, 5, 2016
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17RA
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![BU of 17ra by Molmil](/molmil-images/mine/17ra) | |
4F92
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![BU of 4f92 by Molmil](/molmil-images/mine/4f92) | Brr2 Helicase Region S1087L | 分子名称: | SULFANILAMIDE, U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.662 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F91
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![BU of 4f91 by Molmil](/molmil-images/mine/4f91) | Brr2 Helicase Region | 分子名称: | U5 small nuclear ribonucleoprotein 200 kDa helicase | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F93
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![BU of 4f93 by Molmil](/molmil-images/mine/4f93) | Brr2 Helicase Region S1087L, Mg-ATP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C. | 登録日 | 2012-05-18 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome. Proc.Natl.Acad.Sci.USA, 109, 2012
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2QNA
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![BU of 2qna by Molmil](/molmil-images/mine/2qna) | Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) | 分子名称: | Importin subunit beta-1, SULFATE ION, Snurportin-1 | 著者 | Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R. | 登録日 | 2007-07-18 | 公開日 | 2008-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374, 2007
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6N3E
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![BU of 6n3e by Molmil](/molmil-images/mine/6n3e) | Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 | 分子名称: | FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ... | 著者 | Loerch, S, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2018-11-15 | 公開日 | 2019-01-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.893 Å) | 主引用文献 | The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
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6SLO
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![BU of 6slo by Molmil](/molmil-images/mine/6slo) | Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine | 分子名称: | 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60 | 著者 | Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M. | 登録日 | 2019-08-20 | 公開日 | 2020-09-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly. Nat Commun, 11, 2020
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4H7W
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![BU of 4h7w by Molmil](/molmil-images/mine/4h7w) | |