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8BCB
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BU of 8bcb by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 34
分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, SULFANILAMIDE, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCA
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BU of 8bca by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 26
分子名称: 1,2-ETHANEDIOL, 3-azanyl-~{N}-methyl-4-(methylamino)benzenesulfonamide, GLYCEROL, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCF
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BU of 8bcf by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 78
分子名称: 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCE
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BU of 8bce by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 76
分子名称: 1,2-ETHANEDIOL, N-methoxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCG
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BU of 8bcg by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 86
分子名称: 1,2-ETHANEDIOL, 4-chloranyl-~{N}-methoxy-~{N}-methyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BC8
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BU of 8bc8 by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 18
分子名称: 1,2-ETHANEDIOL, 3-azanyl-4-oxidanyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BCD
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BU of 8bcd by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 50
分子名称: Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, phenylsulfonylcarbamodithioic acid
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
8BC9
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BU of 8bc9 by Molmil
Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 24
分子名称: 1,2-ETHANEDIOL, N-hydroxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ...
著者Vester, K, Loll, B, Wahl, M.C.
登録日2022-10-15
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2.
Acta Crystallogr D Struct Biol, 79, 2023
3HIB
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BU of 3hib by Molmil
Crystal structure of the second Sec63 domain of yeast Brr2
分子名称: Pre-mRNA-splicing helicase BRR2
著者Zhang, L, Xu, T, Zhao, R.
登録日2009-05-19
公開日2009-06-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.
Nat.Struct.Mol.Biol., 16, 2009
2F88
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BU of 2f88 by Molmil
Solution NMR structure of domain 5 from the Pyaiella littoralis (PL) group II intron
分子名称: D5-PL RNA RIBOZYME DOMAIN
著者Dayie, K.T.
登録日2005-12-02
公開日2006-02-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of a self-splicing group II intron catalytic effector domain 5: parallels with spliceosomal U6 RNA
Rna, 12, 2006
5HHK
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BU of 5hhk by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group (Se-MET)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
著者Zhao, C, Pyle, A.M.
登録日2016-01-11
公開日2016-05-04
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHJ
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BU of 5hhj by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P21 space group
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, PHOSPHATE ION, ...
著者Zhao, C, Pyle, A.M.
登録日2016-01-11
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5HHL
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BU of 5hhl by Molmil
Reverse transcriptase domain of group II intron maturase from Eubacterium rectale in P21 space group
分子名称: POTASSIUM ION, Retron-type reverse transcriptase
著者Zhao, C, Pyle, A.M.
登録日2016-01-11
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRG
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BU of 5irg by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P212121 space group
分子名称: POTASSIUM ION, Retron-type reverse transcriptase
著者Zhao, C, Pyle, A.M.
登録日2016-03-13
公開日2016-05-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
5IRF
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BU of 5irf by Molmil
Reverse transcriptase domain of group II intron maturase from Roseburia intestinalis in P1 space group
分子名称: POTASSIUM ION, Retron-type reverse transcriptase
著者Zhao, C, Pyle, A.M.
登録日2016-03-13
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of a group II intron maturase reveal a missing link in spliceosome evolution.
Nat.Struct.Mol.Biol., 23, 2016
1D3B
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BU of 1d3b by Molmil
CRYSTAL STRUCTURE OF THE D3B SUBCOMPLEX OF THE HUMAN CORE SNRNP DOMAIN AT 2.0A RESOLUTION
分子名称: CITRIC ACID, GLYCEROL, PROTEIN (SMALL NUCLEAR RIBONUCLEOPROTEIN ASSOCIATED PROTEIN B), ...
著者Kambach, C, Walke, S, Avis, J.M, De La Fortelle, E, Li, J, Nagai, K.
登録日1998-12-22
公開日1999-12-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs.
Cell(Cambridge,Mass.), 96, 1999
5MF9
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BU of 5mf9 by Molmil
Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
分子名称: RNA-binding protein 5, Survival motor neuron protein
著者Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
登録日2016-11-17
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
17RA
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BU of 17ra by Molmil
BRANCHPOINT HELIX FROM YEAST AND BINDING SITE FOR PHAGE GA/MS2 COAT PROTEINS, NMR, 12 STRUCTURES
分子名称: RNA
著者Nikonowicz, E.P, Smith, J.S.
登録日1998-08-04
公開日1999-04-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure and dynamics of an RNA motif common to the spliceosome branch-point helix and the RNA-binding site for phage GA coat protein.
Biochemistry, 37, 1998
4F92
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BU of 4f92 by Molmil
Brr2 Helicase Region S1087L
分子名称: SULFANILAMIDE, U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C.
登録日2012-05-18
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.662 Å)
主引用文献Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F91
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BU of 4f91 by Molmil
Brr2 Helicase Region
分子名称: U5 small nuclear ribonucleoprotein 200 kDa helicase
著者Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C.
登録日2012-05-18
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F93
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BU of 4f93 by Molmil
Brr2 Helicase Region S1087L, Mg-ATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Santos, K.F, Jovin, S.M, Weber, G, Pena, V, Luehrmann, R, Wahl, M.C.
登録日2012-05-18
公開日2012-10-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Proc.Natl.Acad.Sci.USA, 109, 2012
2QNA
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BU of 2qna by Molmil
Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65)
分子名称: Importin subunit beta-1, SULFATE ION, Snurportin-1
著者Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R.
登録日2007-07-18
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus.
J.Mol.Biol., 374, 2007
6N3E
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BU of 6n3e by Molmil
Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4
分子名称: FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ...
著者Loerch, S, Jenkins, J.L, Kielkopf, C.L.
登録日2018-11-15
公開日2019-01-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.
J. Biol. Chem., 294, 2019
6SLO
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BU of 6slo by Molmil
Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine
分子名称: 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60
著者Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M.
登録日2019-08-20
公開日2020-09-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat Commun, 11, 2020
4H7W
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BU of 4h7w by Molmil
Crystal Structure of Human C16orf57
分子名称: CHLORIDE ION, GLYCEROL, UPF0406 protein C16orf57
著者Hilcenko, C, Simpson, P.J, Warren, A.J.
登録日2012-09-21
公開日2013-02-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia.
Blood, 121, 2013

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