PDB: 19326 件ウェブページステータス検索Chemie searchBIRD

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3QLH	HIV-1 Reverse Transcriptase in Complex with Manicol at the RNase H Active Site and TMC278 (Rilpivirine) at the NNRTI Binding Pocket 分子名称: (2S)-5,7-dihydroxy-9-methyl-2-(prop-1-en-2-yl)-1,2,3,4-tetrahydro-6H-benzo[7]annulen-6-one, 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, ... 著者 Himmel, D.M, Wojtak, K, Bauman, J.D, Arnold, E. 登録日 2011-02-02 公開日 2011-12-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Synthesis, activity, and structural analysis of novel alpha-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. J.Med.Chem., 54, 2011
3G43	Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Fallon, J.L, Quiocho, F.A. 登録日 2009-02-03 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins. Proc.Natl.Acad.Sci.USA, 106, 2009
3G4Z	Crystal Structure of NiSOD Y9F mutant at 1.9 A 分子名称: BROMIDE ION, NICKEL (II) ION, Superoxide dismutase [Ni] 著者 Garman, S.C, Guce, A.I, Herbst, R.W, Bryngelson, P.A, Cabelli, D.E, Higgins, K.A, Ryan, K.C, Maroney, M.J. 登録日 2009-02-04 公開日 2009-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution Biochemistry, 48, 2009
3G5D	Kinase domain of cSrc in complex with Dasatinib 分子名称: GLYCEROL, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src 著者 Grutter, C, Kluter, S, Rauh, D. 登録日 2009-02-05 公開日 2009-06-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc J.Med.Chem., 52, 2009
3QGJ	1.3A Structure of alpha-Lytic Protease Bound to Ac-AlaAlaPro-Alanal 分子名称: 1,2-ETHANEDIOL, Ac-AlaAlaPro-Alanal peptide, Alpha-lytic protease, ... 著者 Everill, P, Meinke, G, Bohm, A, Bachovchin, W. 登録日 2011-01-24 公開日 2012-02-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation To be Published
3FUR	Crystal Structure of PPARg in complex with INT131 分子名称: 2,4-dichloro-N-[3,5-dichloro-4-(quinolin-3-yloxy)phenyl]benzenesulfonamide, CHLORIDE ION, Nuclear receptor coactivator 1, ... 著者 Wang, Z, Liu, J, Walker, N. 登録日 2009-01-14 公開日 2009-06-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 INT131: a selective modulator of PPAR gamma. J.Mol.Biol., 386, 2009
3QO1	Monoclinic form of IgG1 Fab fragment (apo form) sharing same Fv as IgA 分子名称: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL 著者 Trajtenberg, F, Correa, A, Buschiazzo, A. 登録日 2011-02-09 公開日 2012-02-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation Acta Crystallogr.,Sect.D, 69, 2013
3G84	Crystal structure of the trimeric neck and carbohydrate recognition domain of R343V mutant of human surfactant protein D in complex with alpha 1,2 dimannose. 分子名称: CALCIUM ION, Pulmonary surfactant-associated protein D, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose 著者 Head, J.F. 登録日 2009-02-11 公開日 2009-03-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343. Biochemistry, 48, 2009
3QPN	Structure of PDE10-inhibitor complex 分子名称: 6-methoxy-7-[2-(quinolin-2-yl)ethoxy]quinazoline, MAGNESIUM ION, SULFATE ION, ... 著者 Pandit, J, Marr, E.S. 登録日 2011-02-14 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Use of Structure-Based Design to Discover a Potent, Selective, In Vivo Active Phosphodiesterase 10A Inhibitor Lead Series for the Treatment of Schizophrenia. J.Med.Chem., 54, 2011
3QH7	2.5 A resolution structure of Se-Met labeled CT296 from Chlamydia trachomatis 分子名称: CT296 著者 Kemege, K, Hickey, J, Lovell, S, Battaile, K.P, Zhang, Y, Hefty, P.S. 登録日 2011-01-25 公開日 2011-10-05 最終更新日 2018-10-10 実験手法 X-RAY DIFFRACTION (2.497 Å) 主引用文献 Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes. J. Bacteriol., 193, 2011
3FVQ	Crystal structure of the nucleotide binding domain FbpC complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Fe(3+) ions import ATP-binding protein fbpC 著者 Newstead, S, Bilton, P, Carpenter, E.P, Campopiano, D, Iwata, S. 登録日 2009-01-16 公開日 2009-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into how nucleotide-binding domains power ABC transport. Structure, 17, 2009
3QHX	Crystal Structure of Cystathionine gamma-synthase MetB (Cgs) from Mycobacterium ulcerans Agy99 bound to HEPES 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cystathionine gamma-synthase MetB (Cgs), GLYCEROL, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-01-26 公開日 2011-03-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of the cystathionine [gamma]-synthase MetB from Mycobacterium ulcerans Acta Crystallogr.,Sect.F, 67, 2011
3QR9	Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (apo structure) 分子名称: Anthranilate phosphoribosyltransferase, GLYCEROL 著者 Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2011-02-17 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition. Biochemistry, 52, 2013
3QIX	Crystal Structure of BoNT/A LC with Zinc bound 分子名称: 1,2-ETHANEDIOL, Botulinum neurotoxin type A, ZINC ION 著者 Thompson, A.A, Han, G.W, Stevens, R.C. 登録日 2011-01-28 公開日 2011-04-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.413 Å) 主引用文献 Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry, 50, 2011
3FX0	Crystal structure of Human NEMO CC2_LZ domain 分子名称: NF-kappa-B essential modulator 著者 Lo, Y.C, Lin, S.C, Wu, H. 登録日 2009-01-19 公開日 2009-04-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for recognition of diubiquitins by NEMO. Mol.Cell, 33, 2009
3GAH	Structure of a F112H variant PduO-type ATP:corrinoid adenosyltransferase from Lactobacillus reuteri complexed with cobalamin and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, COBALAMIN, Cobalamin adenosyltransferase PduO-like protein, ... 著者 St Maurice, M, Mera, P.E, Escalante-Semerena, J.C, Rayment, I. 登録日 2009-02-17 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. Biochemistry, 48, 2009
3QSI	Nickel binding domain of NikR from Helicobacter pylori disclosing partial metal occupancy 分子名称: NICKEL (II) ION, NikR nickel-responsive regulator, SULFATE ION 著者 Gonzalez, J.M, Pozharski, E. 登録日 2011-02-21 公開日 2012-04-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect. Proc.Natl.Acad.Sci.USA, 109, 2012
3QU1	Peptide deformylase from Vibrio cholerae 分子名称: CHLORIDE ION, Peptide deformylase 2, SULFATE ION, ... 著者 Osipiuk, J, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-02-23 公開日 2011-03-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Peptide deformylase from Vibrio cholerae. To be Published
3QK7	Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001 分子名称: Transcriptional regulators 著者 Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2011-01-31 公開日 2011-02-09 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001 To be Published
3GCN	Crystal structure of DegS H198P/D320A mutant modified by DFP in complex with OMP peptide (YQF) 分子名称: Protease degS, YQF peptide 著者 Sohn, J, Sauer, R.T, Grant, R.A. 登録日 2009-02-22 公開日 2009-03-31 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 Mechanisms of allosteric activation of the DegS protease by OMP-peptide binding and protein-substrate binding To be Published
3QUF	The structure of a family 1 extracellular solute-binding protein from Bifidobacterium longum subsp. infantis 分子名称: ACETIC ACID, Extracellular solute-binding protein, family 1, ... 著者 Cuff, M.E, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-02-23 公開日 2011-05-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The structure of a family 1 extracellular solute-binding protein from Bifidobacterium longum subsp. infantis TO BE PUBLISHED
3FYM	The 1A structure of YmfM, a putative DNA-binding membrane protein from Staphylococcus aureus 分子名称: Putative uncharacterized protein, ZINC ION 著者 Xu, L, Sedelnikova, S.E, Baker, P.J, Rice, D.W. 登録日 2009-01-22 公開日 2010-02-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 The 1A structure of YmfM, a putative DNA-binding membrane protein from Staphylococcus aureus To be Published
3QL2	Crystal Structure of Ribonuclease A Variant A4C/D83E/V118C 分子名称: Ribonuclease pancreatic, SULFATE ION 著者 Arnold, U, Schoepfel, M. 登録日 2011-02-02 公開日 2012-02-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Significant stabilization of ribonuclease A by additive effects Febs J., 279, 2012
3QV2	Structure Analysis of Entamoeba histolytica methyltransferase EhMeth 分子名称: 5-cytosine DNA methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Schulz, E.C, Roth, H.M, Ankri, S, Ficner, R. 登録日 2011-02-25 公開日 2012-04-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure Analysis of Entamoeba histolytica Methyltransferase To be Published
3QLN	Crystal structure of ATRX ADD domain in free state 分子名称: Transcriptional regulator ATRX, ZINC ION 著者 Li, H, Patel, D.J. 登録日 2011-02-03 公開日 2011-06-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome Nat.Struct.Mol.Biol., 18, 2011

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